Detailed information NTG0793135

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: PWA59_RS18525
• Genome accession: NZ_CP118541
• Coordinates: 3687106..3688269 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain HC-5
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3682106..3693269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PWA59_RS18495 (PWA59_18495)	-	3682371..3682790 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
PWA59_RS18500 (PWA59_18500)	comFC	3682864..3683553 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
PWA59_RS18505 (PWA59_18505)	-	3683559..3683843 (-)	285	WP_014419011.1	competence protein ComFB	-
PWA59_RS18510 (PWA59_18510)	comFA	3683901..3685286 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
PWA59_RS18515 (PWA59_18515)	-	3685394..3686242 (-)	849	WP_003151387.1	DegV family protein	-
PWA59_RS18520 (PWA59_18520)	degU	3686340..3687029 (-)	690	WP_111927758.1	two-component system response regulator DegU	Regulator
PWA59_RS18525 (PWA59_18525)	degS	3687106..3688269 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
PWA59_RS18530 (PWA59_18530)	-	3688492..3689139 (+)	648	WP_007614107.1	YigZ family protein	-
PWA59_RS18535 (PWA59_18535)	-	3689144..3690358 (+)	1215	WP_014419013.1	LCP family protein	-
PWA59_RS18540 (PWA59_18540)	-	3690448..3691524 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
PWA59_RS18545 (PWA59_18545)	-	3691657..3692853 (-)	1197	WP_014419014.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=793135 PWA59_RS18525 WP_007407484.1 3687106..3688269(-) (degS) [Bacillus velezensis strain HC-5]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=793135 PWA59_RS18525 WP_007407484.1 3687106..3688269(-) (degS) [Bacillus velezensis strain HC-5]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951