Detailed information NTG0791477

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PVK49_RS04510
• Genome accession: NZ_CP118306
• Coordinates: 892961..893797 (-)
• Length: 278 a.a.
• NCBI ID: WP_047235811.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 20154608
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 887961..898797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PVK49_RS04490 (PVK49_04480)	-	888181..889173 (-)	993	WP_047235809.1	D-lactate dehydrogenase	-
PVK49_RS04495 (PVK49_04485)	-	889188..889754 (-)	567	Protein_825	PTS sugar transporter subunit IIC	-
PVK49_RS04500 (PVK49_04490)	-	889794..890651 (+)	858	Protein_826	LysR family transcriptional regulator	-
PVK49_RS04505 (PVK49_04495)	topA	890726..892855 (-)	2130	WP_047235810.1	type I DNA topoisomerase	-
PVK49_RS04510 (PVK49_04500)	dprA	892961..893797 (-)	837	WP_047235811.1	DNA-processing protein DprA	Machinery gene
PVK49_RS04515 (PVK49_04505)	-	893862..894653 (-)	792	WP_002995007.1	ribonuclease HII	-
PVK49_RS04520 (PVK49_04510)	ylqF	894643..895491 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
PVK49_RS04525 (PVK49_04515)	-	895710..896150 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
PVK49_RS04530 (PVK49_04520)	-	896147..896797 (+)	651	WP_002984629.1	hemolysin III family protein	-
PVK49_RS04535 (PVK49_04525)	-	896914..897825 (+)	912	WP_047235812.1	diacylglycerol kinase family protein	-
PVK49_RS04540 (PVK49_04530)	-	897875..898249 (-)	375	WP_397611202.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30993.02 Da
• Isoelectric Point: 9.2511

>NTDB_id=791477 PVK49_RS04510 WP_047235811.1 892961..893797(-) (dprA) [Streptococcus pyogenes strain 20154608]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIISGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=791477 PVK49_RS04510 WP_047235811.1 892961..893797(-) (dprA) [Streptococcus pyogenes strain 20154608]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTATTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGCCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568