Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   PVK49_RS01425 Genome accession   NZ_CP118306
Coordinates   268002..269072 (+) Length   356 a.a.
NCBI ID   WP_009880666.1    Uniprot ID   Q54910
Organism   Streptococcus pyogenes strain 20154608     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 263002..274072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK49_RS01410 (PVK49_01410) amiA 263530..265500 (+) 1971 WP_047235658.1 peptide ABC transporter substrate-binding protein Regulator
  PVK49_RS01415 (PVK49_01415) amiC 265565..267067 (+) 1503 WP_047235659.1 ABC transporter permease Regulator
  PVK49_RS01420 (PVK49_01420) amiD 267067..267993 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  PVK49_RS01425 (PVK49_01425) amiE 268002..269072 (+) 1071 WP_009880666.1 ABC transporter ATP-binding protein Regulator
  PVK49_RS01430 (PVK49_01430) amiF 269065..269988 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  PVK49_RS01435 - 270026..270109 (-) 84 Protein_235 IS3 family transposase -
  PVK49_RS01440 - 270243..270553 (-) 311 Protein_236 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39645.74 Da        Isoelectric Point: 5.8952

>NTDB_id=791460 PVK49_RS01425 WP_009880666.1 268002..269072(+) (amiE) [Streptococcus pyogenes strain 20154608]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQGLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=791460 PVK49_RS01425 WP_009880666.1 268002..269072(+) (amiE) [Streptococcus pyogenes strain 20154608]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGGTTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q54910

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537