Detailed information NTG0789871

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: PUW52_RS10625
• Genome accession: NZ_CP118078
• Coordinates: 2083442..2084632 (+)
• Length: 396 a.a.
• NCBI ID: WP_070812015.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain VSI16
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2078442..2089632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW52_RS10600 (PUW52_10600)	comE	2080249..2080998 (-)	750	WP_022526721.1	competence system response regulator transcription factor ComE	Regulator
PUW52_RS10605 (PUW52_10605)	comD/comD2	2080998..2082323 (-)	1326	WP_274984617.1	GHKL domain-containing protein	Regulator
PUW52_RS10610 (PUW52_10610)	-	2082341..2082487 (-)	147	WP_003029519.1	bacteriocin	-
PUW52_RS10620 (PUW52_10620)	rlmH	2082769..2083248 (-)	480	WP_024052476.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
PUW52_RS10625 (PUW52_10625)	htrA	2083442..2084632 (+)	1191	WP_070812015.1	trypsin-like peptidase domain-containing protein	Regulator
PUW52_RS10630 (PUW52_10630)	spo0J	2084687..2085454 (+)	768	WP_274984540.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41667.61 Da
• Isoelectric Point: 9.4264

>NTDB_id=789871 PUW52_RS10625 WP_070812015.1 2083442..2084632(+) (htrA) [Streptococcus anginosus strain VSI16]
MKNSSNFTKKLLLLFMVLAIGFIGGLLGNLTSSKLSTNSSTTTKVNQVTTAYKNTNSTTQAVSKVKDAVVSVITYANNNS
QNSVFGNDDSNNNNDNSQQVASEGSGVIYKKDGKYAYLVTNTHVISGAKKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ADKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDVINIINQLEANGTVTRPALGIQMIDITNLSSSDLSRLKLPSKITSGV
VVRSAQSGMPSEGKLQKYDVITKVDDKEISSTSDLQSALYKHSIGDNIKITFYRDGKETTTTIKLTKSTKDLDSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=789871 PUW52_RS10625 WP_070812015.1 2083442..2084632(+) (htrA) [Streptococcus anginosus strain VSI16]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTGTTATTGCTTTTCATGGTCTTAGCTATAGGTTTTATCGGTGGTTTACT
TGGAAACTTAACTTCATCTAAATTATCAACAAATAGCTCTACAACGACTAAAGTTAATCAAGTTACTACTGCTTATAAAA
ATACAAATTCCACAACACAAGCTGTGAGTAAAGTGAAAGATGCTGTGGTATCCGTTATTACCTATGCTAATAATAATTCA
CAAAACAGCGTGTTTGGAAATGATGATTCAAATAATAACAATGATAATTCTCAACAAGTAGCTAGCGAAGGATCTGGGGT
TATTTATAAAAAAGATGGAAAATACGCTTACTTAGTAACCAATACTCACGTTATCAGTGGTGCTAAAAAAGTTGACATTC
GTTTAGCAGATGGTAATAAAGTTCCTGGAGAAATTGTAGGGTCAGATACTTATTCTGATATCTCCGTTGTTCGAATTAGT
GCTGATAAAGTAAAATCAGTTGCTGAATTTGGAGATTCTAGTAAATTGACGGTTGGTGAGACAGCTATTGCGATTGGAAG
TCCGCTCGGATCAAATTACGCTAACACTGTGACGCAAGGAATTATTTCTAGTTTAAATCGTAATGTTTCTTTAAAATCTG
AAGACGGACAAACGATTTCAACACAAGCTATTCAAACAGACACAGCTATTAACCCAGGGAACTCTGGTGGACCACTTGTG
AATATCCAAGGACAAGTAATTGGTATTACTTCAAGTAAAATAGCTAGCAACGGCGGAACTTCGGTTGAAGGATTAGGATT
TGCTATTCCATCTAATGATGTTATAAACATTATTAACCAGTTAGAAGCAAATGGAACTGTTACACGACCAGCTCTAGGAA
TCCAAATGATTGACATCACTAATCTGTCTAGTTCAGATCTATCACGCTTAAAACTTCCATCAAAAATAACTAGTGGAGTT
GTCGTACGTTCAGCTCAATCTGGAATGCCATCTGAAGGAAAACTTCAAAAATATGATGTGATTACAAAAGTAGATGATAA
AGAAATTTCTTCAACAAGTGATTTACAATCCGCTTTATACAAACATTCAATTGGTGACAACATAAAAATCACTTTCTATC
GTGATGGAAAAGAAACTACTACTACCATTAAGCTTACAAAATCTACAAAAGATTTAGATTCAAATAATTGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (290-385)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	75.312	100	0.763
htrA	Streptococcus mitis NCTC 12261	72.292	100	0.725
htrA	Streptococcus pneumoniae Rx1	72.04	100	0.722
htrA	Streptococcus pneumoniae D39	72.04	100	0.722
htrA	Streptococcus pneumoniae R6	72.04	100	0.722
htrA	Streptococcus pneumoniae TIGR4	72.04	100	0.722
htrA	Streptococcus mutans UA159	55.216	99.242	0.548