Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   PUW52_RS03550 Genome accession   NZ_CP118078
Coordinates   699004..699705 (+) Length   233 a.a.
NCBI ID   WP_003025150.1    Uniprot ID   A0A2I1UXK8
Organism   Streptococcus anginosus strain VSI16     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 694004..704705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW52_RS03530 (PUW52_03530) ccpA 694945..695949 (+) 1005 WP_117625130.1 catabolite control protein A Regulator
  PUW52_RS03535 (PUW52_03535) - 696042..697040 (+) 999 WP_024051860.1 glycosyltransferase -
  PUW52_RS03540 (PUW52_03540) - 697042..698355 (+) 1314 WP_024051859.1 glycosyltransferase family 4 protein -
  PUW52_RS03545 (PUW52_03545) - 698382..698723 (+) 342 WP_070812132.1 hypothetical protein -
  PUW52_RS03550 (PUW52_03550) micA 699004..699705 (+) 702 WP_003025150.1 response regulator YycF Regulator
  PUW52_RS03555 (PUW52_03555) micB 699698..701050 (+) 1353 WP_003032751.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PUW52_RS03560 (PUW52_03560) vicX 701052..701855 (+) 804 WP_024051857.1 MBL fold metallo-hydrolase Regulator
  PUW52_RS03565 (PUW52_03565) - 701934..702203 (+) 270 Protein_663 YbaN family protein -
  PUW52_RS03570 (PUW52_03570) rnc 702584..703282 (+) 699 WP_003025140.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26887.86 Da        Isoelectric Point: 4.6824

>NTDB_id=789844 PUW52_RS03550 WP_003025150.1 699004..699705(+) (micA) [Streptococcus anginosus strain VSI16]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=789844 PUW52_RS03550 WP_003025150.1 699004..699705(+) (micA) [Streptococcus anginosus strain VSI16]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAGCCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTTGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGCGAATTTGACAAAGTTATTGGTCTTGAAATCGGTGCGGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361