Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   PUW52_RS02240 Genome accession   NZ_CP118078
Coordinates   424837..426138 (+) Length   433 a.a.
NCBI ID   WP_070241559.1    Uniprot ID   A0A413KQY1
Organism   Streptococcus anginosus strain VSI16     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 419837..431138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW52_RS02220 (PUW52_02220) - 421758..422192 (+) 435 WP_070241558.1 hypothetical protein -
  PUW52_RS02225 (PUW52_02225) dcm 422349..422794 (+) 446 Protein_396 DNA (cytosine-5-)-methyltransferase -
  PUW52_RS02230 (PUW52_02230) cysK 423116..424045 (-) 930 WP_024052086.1 cysteine synthase A -
  PUW52_RS02235 (PUW52_02235) - 424145..424780 (-) 636 WP_024052085.1 YigZ family protein -
  PUW52_RS02240 (PUW52_02240) comFA/cflA 424837..426138 (+) 1302 WP_070241559.1 DEAD/DEAH box helicase Machinery gene
  PUW52_RS02245 (PUW52_02245) comFC/cflB 426135..426800 (+) 666 WP_024052083.1 ComF family protein Machinery gene
  PUW52_RS02250 (PUW52_02250) raiA 426878..427420 (+) 543 WP_003025754.1 ribosome-associated translation inhibitor RaiA -
  PUW52_RS02255 (PUW52_02255) rsmD 427608..428156 (+) 549 WP_171021853.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  PUW52_RS02260 (PUW52_02260) coaD 428146..428644 (+) 499 Protein_403 pantetheine-phosphate adenylyltransferase -
  PUW52_RS02265 (PUW52_02265) sepM 428625..429680 (+) 1056 WP_024052081.1 SepM family pheromone-processing serine protease Regulator
  PUW52_RS02270 (PUW52_02270) - 429819..430382 (+) 564 WP_024052080.1 YutD-like domain-containing protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49099.88 Da        Isoelectric Point: 8.0430

>NTDB_id=789831 PUW52_RS02240 WP_070241559.1 424837..426138(+) (comFA/cflA) [Streptococcus anginosus strain VSI16]
MTELQDCLGRIFTKNQLSPELQLQAQTLTGMVEEKGRLSCNRCGQAIDKEKHQLPIGAYYCRSCLILGRVRSDEDLYYFP
QEEFPKANVLKWQGKLTEFQAKVSQGLVEAVTKRKDSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKVDFTCDISLLHGESEAYSRSPLVIATTHQLIKFYRAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPQKIWLADFQKYLGQKKLVPKLRQFIQKQRKTGFPLLIFASEIRKGQELAE
ILQSTFPNEEVDFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSME
RPTGELIFFHDGTTMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=789831 PUW52_RS02240 WP_070241559.1 424837..426138(+) (comFA/cflA) [Streptococcus anginosus strain VSI16]
ATGACAGAATTACAAGATTGTTTAGGTCGCATTTTTACAAAAAATCAACTGTCACCAGAATTGCAATTGCAAGCACAAAC
CTTAACTGGAATGGTAGAAGAAAAAGGGAGATTAAGCTGTAATCGCTGTGGACAAGCCATTGACAAAGAAAAACACCAAC
TGCCAATCGGTGCTTATTATTGTAGGTCTTGCTTGATCTTAGGAAGAGTTAGGAGTGATGAAGATCTCTACTATTTTCCA
CAGGAAGAATTTCCCAAAGCGAATGTCTTGAAATGGCAAGGAAAGTTGACAGAATTTCAAGCCAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTACCAAACGCAAAGATAGCTTGGTTCACGCAGTCACGGGAGCCGGAAAGACGGAAATGATCTATCAAG
TGGTGGCACAAGTCATCAATCAGGGCGGAGCAGTCTGCTTGGCTAGCCCCAGAATTGATGTCTGCTTAGAACTTTATCGC
AGACTGAAAGTGGATTTTACTTGTGATATTTCACTCCTGCACGGTGAATCAGAAGCATATTCTCGCAGTCCTCTCGTGAT
TGCCACCACACATCAGCTTATCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGATGAGGTAGATGCCTTTCCTTATG
TGGACAATCCGATGCTTTATCATGCAGTTCATCAGGCAGTCAAAGTAGAGGGGACGAAGATTTTCTTAACAGCAACTTCC
ACAGATGAGCTGGATAAAAAAGTGGCTAAAGGAGAATTAACTCGTTTGAGTCTACCCAGACGTTTTCATGGCAATCCTTT
GATTGTTCCGCAAAAAATTTGGTTGGCGGATTTTCAAAAATATCTTGGTCAAAAGAAGCTAGTTCCCAAGTTAAGGCAGT
TTATTCAAAAGCAGAGAAAAACAGGATTTCCACTTCTTATTTTTGCTTCCGAGATCAGAAAAGGGCAGGAGCTGGCAGAG
ATTCTTCAAAGCACTTTTCCTAATGAAGAAGTTGATTTTGTAGCCTCGACGACTGAAAATCGACTAGAAATTGTAGAGAA
ATTTCGTCAAAAAGAAATCACGATTTTGGTAACGACGACAATTTTGGAGCGTGGGGTGACTTTTCCTTGTGTAGATGTTT
TCGTGGTGGAAGCCAACCACCGTCTGTTTAGTCGCAGCGCTCTGGTACAAATTGCTGGACGCGTTGGTCGCAGTATGGAG
CGACCGACAGGCGAGTTAATCTTTTTTCATGACGGTACGACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCCGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(108-245)

Helicase conserved C-terminal domain (Helicase_C)

(291-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KQY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae D39

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae R6

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae TIGR4

70.794

98.845

0.7
  comFA/cflA Streptococcus mitis NCTC 12261

70.892

98.383

0.697
  comFA/cflA Streptococcus mitis SK321

70.423

98.383

0.693
  comFA Lactococcus lactis subsp. cremoris KW2

55.276

91.917

0.508
  comFA Latilactobacillus sakei subsp. sakei 23K

40.092

100

0.402
  comFA Bacillus subtilis subsp. subtilis str. 168

40.247

93.533

0.376