Detailed information NTG0789833

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: PUW52_RS02265
• Genome accession: NZ_CP118078
• Coordinates: 428625..429680 (+)
• Length: 351 a.a.
• NCBI ID: WP_024052081.1
• Uniprot ID: A0A413KQY5
• Organism: Streptococcus anginosus strain VSI16
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 423625..434680

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW52_RS02235 (PUW52_02235)	-	424145..424780 (-)	636	WP_024052085.1	YigZ family protein	-
PUW52_RS02240 (PUW52_02240)	comFA/cflA	424837..426138 (+)	1302	WP_070241559.1	DEAD/DEAH box helicase	Machinery gene
PUW52_RS02245 (PUW52_02245)	comFC/cflB	426135..426800 (+)	666	WP_024052083.1	ComF family protein	Machinery gene
PUW52_RS02250 (PUW52_02250)	raiA	426878..427420 (+)	543	WP_003025754.1	ribosome-associated translation inhibitor RaiA	-
PUW52_RS02255 (PUW52_02255)	rsmD	427608..428156 (+)	549	WP_171021853.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
PUW52_RS02260 (PUW52_02260)	coaD	428146..428644 (+)	499	Protein_403	pantetheine-phosphate adenylyltransferase	-
PUW52_RS02265 (PUW52_02265)	sepM	428625..429680 (+)	1056	WP_024052081.1	SepM family pheromone-processing serine protease	Regulator
PUW52_RS02270 (PUW52_02270)	-	429819..430382 (+)	564	WP_024052080.1	YutD-like domain-containing protein	-
PUW52_RS02275 (PUW52_02275)	rlmN	430423..431505 (+)	1083	WP_024052079.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
PUW52_RS02280 (PUW52_02280)	-	431498..432028 (+)	531	WP_024052078.1	VanZ family protein	-
PUW52_RS02285 (PUW52_02285)	trpB	432389..433597 (+)	1209	Protein_408	tryptophan synthase subunit beta	-
PUW52_RS02290 (PUW52_02290)	cclA/cilC	433758..434417 (-)	660	WP_024052075.1	A24 family peptidase	Machinery gene

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38290.25 Da
• Isoelectric Point: 10.1906

>NTDB_id=789833 PUW52_RS02265 WP_024052081.1 428625..429680(+) (sepM) [Streptococcus anginosus strain VSI16]
MEKPRNKFKKWPIIAVVGVILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATLAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=789833 PUW52_RS02265 WP_024052081.1 428625..429680(+) (sepM) [Streptococcus anginosus strain VSI16]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGGTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCCTCGCTCATTTGGTTTATGCTTGGCTG
ACACCTTTTACGGATATTTATTCGGCGAAGGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAGTCTGCTACAGGTAAAATTATTAAACTTGAAAATGGGAAAAACGGGATTGGCATTAGTT
TGATTGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACAGGTTCGAT
TGACCGAGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAGAG
CACAAAAAAGTCGTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-307)

• PDZ domain (PDZ_2) (133-197)

3D structure

• AlphaFold DB: A0A413KQY5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	64.223	97.151	0.624