Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   PUW52_RS02245 Genome accession   NZ_CP118078
Coordinates   426135..426800 (+) Length   221 a.a.
NCBI ID   WP_024052083.1    Uniprot ID   A0A412PNM5
Organism   Streptococcus anginosus strain VSI16     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 421135..431800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW52_RS02220 (PUW52_02220) - 421758..422192 (+) 435 WP_070241558.1 hypothetical protein -
  PUW52_RS02225 (PUW52_02225) dcm 422349..422794 (+) 446 Protein_396 DNA (cytosine-5-)-methyltransferase -
  PUW52_RS02230 (PUW52_02230) cysK 423116..424045 (-) 930 WP_024052086.1 cysteine synthase A -
  PUW52_RS02235 (PUW52_02235) - 424145..424780 (-) 636 WP_024052085.1 YigZ family protein -
  PUW52_RS02240 (PUW52_02240) comFA/cflA 424837..426138 (+) 1302 WP_070241559.1 DEAD/DEAH box helicase Machinery gene
  PUW52_RS02245 (PUW52_02245) comFC/cflB 426135..426800 (+) 666 WP_024052083.1 ComF family protein Machinery gene
  PUW52_RS02250 (PUW52_02250) raiA 426878..427420 (+) 543 WP_003025754.1 ribosome-associated translation inhibitor RaiA -
  PUW52_RS02255 (PUW52_02255) rsmD 427608..428156 (+) 549 WP_171021853.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  PUW52_RS02260 (PUW52_02260) coaD 428146..428644 (+) 499 Protein_403 pantetheine-phosphate adenylyltransferase -
  PUW52_RS02265 (PUW52_02265) sepM 428625..429680 (+) 1056 WP_024052081.1 SepM family pheromone-processing serine protease Regulator
  PUW52_RS02270 (PUW52_02270) - 429819..430382 (+) 564 WP_024052080.1 YutD-like domain-containing protein -
  PUW52_RS02275 (PUW52_02275) rlmN 430423..431505 (+) 1083 WP_024052079.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25367.43 Da        Isoelectric Point: 7.9118

>NTDB_id=789832 PUW52_RS02245 WP_024052083.1 426135..426800(+) (comFC/cflB) [Streptococcus anginosus strain VSI16]
MNSCVLCENPLDEKLKFCDLLTLTKPKARACDACFEKFQRISGQHCPKCYRDGASEVCMDCQVWIEKGKEVYHKSCFVYN
EAMKDFFSQYKFQGDYALYSVFAAVLQKELKVYRDYALVPIPVSAEKYQTRGFNQVTALLEGAKLPFKEVLEKYDTIAQS
SKTREERLQSRQCFKLKDNVQLPPKILLIDDIYTTGSTLQLAKEILVEAGVKEIVTFSLAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=789832 PUW52_RS02245 WP_024052083.1 426135..426800(+) (comFC/cflB) [Streptococcus anginosus strain VSI16]
ATGAATTCATGTGTTTTATGTGAAAATCCACTTGATGAAAAGCTGAAATTCTGTGATTTATTGACCTTGACGAAGCCAAA
AGCAAGGGCTTGTGATGCCTGCTTTGAAAAATTTCAACGCATTTCAGGGCAGCATTGCCCGAAGTGTTATCGTGACGGGG
CAAGTGAAGTCTGCATGGATTGCCAAGTGTGGATAGAAAAAGGAAAAGAAGTTTACCATAAAAGCTGTTTTGTGTATAAT
GAAGCCATGAAAGACTTCTTCAGTCAATATAAATTTCAAGGAGATTATGCCCTTTATTCTGTATTTGCTGCAGTTTTGCA
AAAGGAATTGAAAGTTTACCGTGATTATGCGCTTGTTCCCATTCCGGTAAGTGCCGAAAAGTATCAGACAAGAGGGTTTA
ATCAAGTAACAGCTCTTCTTGAGGGCGCAAAGTTGCCATTTAAGGAAGTTTTAGAAAAGTATGATACAATTGCTCAATCC
AGTAAAACAAGAGAGGAGCGATTGCAAAGCCGGCAGTGTTTTAAATTGAAAGACAACGTTCAACTTCCACCTAAAATCCT
TTTGATAGATGACATTTATACAACAGGCTCAACCCTACAATTAGCCAAGGAAATTTTAGTGGAAGCAGGAGTGAAAGAAA
TTGTGACATTTTCATTAGCCAGATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PNM5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

49.083

98.643

0.484
  comFC/cflB Streptococcus pneumoniae TIGR4

47.706

98.643

0.471
  comFC/cflB Streptococcus mitis NCTC 12261

47.706

98.643

0.471
  comFC/cflB Streptococcus pneumoniae Rx1

47.248

98.643

0.466
  comFC/cflB Streptococcus pneumoniae D39

47.248

98.643

0.466
  comFC/cflB Streptococcus pneumoniae R6

47.248

98.643

0.466
  comFC Bacillus subtilis subsp. subtilis str. 168

35.683

100

0.367