Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   PUW49_RS03920 Genome accession   NZ_CP118054
Coordinates   776530..777231 (+) Length   233 a.a.
NCBI ID   WP_022526268.1    Uniprot ID   A0AAN4T548
Organism   Streptococcus anginosus strain VSI37     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 771530..782231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS03900 (PUW49_03900) ccpA 772471..773475 (+) 1005 WP_024051861.1 catabolite control protein A Regulator
  PUW49_RS03905 (PUW49_03905) - 773568..774566 (+) 999 WP_024051860.1 glycosyltransferase -
  PUW49_RS03910 (PUW49_03910) - 774568..775881 (+) 1314 WP_024051859.1 glycosyltransferase family 4 protein -
  PUW49_RS03915 (PUW49_03915) - 775908..776249 (+) 342 WP_070811244.1 hypothetical protein -
  PUW49_RS03920 (PUW49_03920) micA 776530..777231 (+) 702 WP_022526268.1 response regulator YycF Regulator
  PUW49_RS03925 (PUW49_03925) micB 777224..778576 (+) 1353 WP_003032751.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PUW49_RS03930 (PUW49_03930) vicX 778578..779381 (+) 804 WP_024051857.1 MBL fold metallo-hydrolase Regulator
  PUW49_RS03935 (PUW49_03935) - 779460..779729 (+) 270 Protein_738 YbaN family protein -
  PUW49_RS03940 (PUW49_03940) rnc 780110..780808 (+) 699 WP_003025140.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26945.90 Da        Isoelectric Point: 4.6298

>NTDB_id=789670 PUW49_RS03920 WP_022526268.1 776530..777231(+) (micA) [Streptococcus anginosus strain VSI37]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHDEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=789670 PUW49_RS03920 WP_022526268.1 776530..777231(+) (micA) [Streptococcus anginosus strain VSI37]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAGCCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTTGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGCGAATTTGACAAAGTTATTGGTCTTGAAATCGGTGCGGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGACGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

100

0.824
  vicR Streptococcus mutans UA159

78.814

100

0.798
  covR Streptococcus salivarius strain HSISS4

45.652

98.712

0.451
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361