Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   PUW49_RS03270 Genome accession   NZ_CP118054
Coordinates   629237..631390 (-) Length   717 a.a.
NCBI ID   WP_142350988.1    Uniprot ID   A0AAW5TH75
Organism   Streptococcus anginosus strain VSI37     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 624237..636390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS03245 (PUW49_03245) - 624675..625388 (+) 714 WP_070811495.1 type II CAAX endopeptidase family protein -
  PUW49_RS03250 (PUW49_03250) - 625526..626271 (+) 746 Protein_602 response regulator transcription factor -
  PUW49_RS03255 (PUW49_03255) - 626305..627600 (+) 1296 WP_024051972.1 GHKL domain-containing protein -
  PUW49_RS03260 (PUW49_03260) - 627622..627771 (-) 150 WP_022526763.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  PUW49_RS03265 (PUW49_03265) - 627865..629226 (-) 1362 WP_070672666.1 bacteriocin secretion accessory protein -
  PUW49_RS03270 (PUW49_03270) comA/nlmT 629237..631390 (-) 2154 WP_142350988.1 peptide cleavage/export ABC transporter Regulator
  PUW49_RS03275 (PUW49_03275) - 631669..632724 (+) 1056 WP_024051969.1 serine hydrolase -
  PUW49_RS03280 (PUW49_03280) - 632860..633546 (+) 687 WP_024051968.1 Crp/Fnr family transcriptional regulator -
  PUW49_RS03285 (PUW49_03285) arcA 633867..635096 (+) 1230 WP_021001457.1 arginine deiminase -
  PUW49_RS03290 (PUW49_03290) argF 635120..636136 (+) 1017 WP_003028184.1 ornithine carbamoyltransferase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80746.27 Da        Isoelectric Point: 9.3981

>NTDB_id=789663 PUW49_RS03270 WP_142350988.1 629237..631390(-) (comA/nlmT) [Streptococcus anginosus strain VSI37]
MVNFKKSFVPQIDARDCGVAALASIAKYYGSNYSLAHLRELAKTNKEGTTALGIVKAAKEMGFETRPIQADMTLFDTEEL
PYPFIAHVNKDGKLQHYYVVYKNEQKHLLIGDPDPTVKITKISKEQFTKEWTGVAIFLAPKPSYKPHKDKKNGLASFLPL
IFKQRSLIFYIVLASLLVTLINIVGSYYLQSVLDEYIPNQMKSTLGIISIGLIIAYILQQMMSFSRDYLLTVLSQRLTID
VILSYIRHIFELPMSFFAMRRTGEIISRFTDANSIIDALASTILSFFLDLFIVMIVGSVLLLQNVNLFLLTLLAIPIYAL
IIFVFMKPFEKMNNDVMQSNAMVHSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKTFKLSKYSIMQTALKQGAQF
VLNVVILWVGASLVMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANHRLNEVYLVESEFKTKQVLTEKNFL
AGDITFHNVSYKYGFGRDTLSDISLTIKKGDKISLFGISGSGKTTLAKMIVHFYEPYQGQIRLNGNDLKTIDKKVLRQYI
NYLPQQAYIFSGSILDNLTLGADQTVSQSDILRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSP
ILILDEATSGLDVLTEKKVIDNLMKLPDKTIIFVAHRLSISKRTNQIIVLDQGKVTEIGSHTELIGRKGFYYHLFNK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=789663 PUW49_RS03270 WP_142350988.1 629237..631390(-) (comA/nlmT) [Streptococcus anginosus strain VSI37]
ATAGTGAATTTTAAAAAATCGTTTGTTCCACAAATAGATGCTAGAGATTGTGGTGTTGCTGCTCTGGCTTCCATTGCTAA
ATACTATGGTTCAAATTATTCTTTAGCACACTTGAGAGAGCTCGCAAAGACAAACAAAGAAGGGACAACTGCACTTGGAA
TTGTCAAAGCAGCAAAAGAAATGGGCTTTGAAACCCGACCAATCCAAGCAGACATGACATTGTTTGATACAGAAGAGCTT
CCCTATCCTTTCATCGCACATGTCAACAAAGACGGCAAGCTTCAACACTATTATGTCGTTTATAAAAACGAGCAAAAGCA
CTTGCTTATCGGTGATCCTGATCCAACTGTCAAAATAACTAAGATTAGCAAAGAACAATTTACTAAAGAATGGACAGGTG
TTGCTATCTTTCTCGCCCCAAAACCTAGCTATAAACCTCATAAGGATAAGAAAAATGGACTTGCTAGCTTTTTACCACTC
ATCTTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTCGTGACCCTCATCAACATTGTTGGCTCCTA
TTATCTGCAAAGTGTTTTGGACGAATACATCCCAAATCAGATGAAATCAACTCTTGGGATTATTTCGATTGGACTTATCA
TTGCCTACATCTTACAGCAAATGATGAGTTTTTCAAGAGACTACCTGCTAACAGTACTCAGTCAACGATTAACAATTGAT
GTGATTTTGTCTTATATTCGGCATATTTTTGAATTGCCAATGTCCTTTTTTGCGATGAGACGCACTGGAGAGATTATTTC
TCGTTTTACAGATGCCAACTCTATTATTGATGCTCTAGCTTCAACTATCCTGTCTTTCTTTCTTGATTTGTTCATTGTGA
TGATTGTCGGTAGTGTTCTTTTACTGCAAAATGTCAATCTCTTTTTACTCACTTTGCTTGCAATTCCTATCTACGCTCTC
ATTATTTTTGTTTTTATGAAGCCCTTTGAAAAAATGAACAACGATGTTATGCAAAGCAATGCTATGGTACATTCTGCCAT
TATCGAAGATATCAATGGAATTGAAACTATTAAATCCTTAACCAGTGAAGAAAGTCGTTACCAGAAGATTGATAGCGAGT
TTGTTGATTATCTGGATAAAACTTTCAAATTAAGTAAATATTCCATTATGCAGACCGCTCTCAAACAAGGAGCACAATTT
GTTTTGAATGTGGTCATTCTCTGGGTTGGAGCGTCCTTAGTCATGTCTCAAAAGATTTCAATTGGTCAACTGATTACTTT
TAATGCACTCCTTTCGTATTTTACAAGCCCGCTTGAAAGTATTATCAATCTTCAAACCAAACTGCAATCAGCTAAAGTTG
CCAATCATCGACTGAATGAAGTTTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCCTTACGGAGAAAAATTTCTTA
GCTGGTGATATTACTTTTCATAACGTCTCCTATAAATATGGCTTTGGACGAGATACTTTATCAGATATTAGTTTAACTAT
CAAGAAGGGAGATAAAATCAGTCTTTTCGGTATTAGCGGTTCGGGAAAAACAACACTTGCTAAGATGATTGTTCATTTTT
ATGAGCCTTATCAAGGACAAATTCGCCTCAATGGAAATGACCTCAAGACAATTGATAAGAAAGTTCTTCGGCAATATATC
AACTACTTACCTCAGCAAGCTTACATCTTTAGTGGTTCCATTCTAGACAACCTCACATTAGGAGCCGATCAAACAGTTTC
TCAATCAGATATTCTTCGTGCCTGTGAAATTGCAGAAATTCGTTCAGATATCGAACAAATGCCCATGGGATACCAGACAG
AATTGTCTGACGGAGCTGGATTATCTGGTGGACAAAAGCAACGAATTGCACTTGCACGCGCTCTGCTGACGAAATCTCCC
ATTCTCATTTTAGATGAAGCAACGAGTGGATTAGATGTTTTAACAGAGAAAAAAGTCATTGATAATCTCATGAAATTACC
CGACAAAACCATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGTACAAATCAGATTATCGTCCTTGACCAAGGAA
AAGTGACTGAAATTGGTTCTCATACTGAATTGATAGGAAGAAAAGGTTTTTATTATCATCTATTTAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-649)

ABC transporter transmembrane region (ABC_membrane)

(168-438)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.779

98.884

0.72
  comA Streptococcus mitis NCTC 12261

67.181

99.442

0.668
  comA Streptococcus mitis SK321

66.76

99.442

0.664
  comA Streptococcus gordonii str. Challis substr. CH1

66.62

99.442

0.662
  comA Streptococcus pneumoniae D39

66.339

99.442

0.66
  comA Streptococcus pneumoniae R6

66.339

99.442

0.66
  comA Streptococcus pneumoniae Rx1

66.339

99.442

0.66
  comA Streptococcus pneumoniae TIGR4

65.919

99.442

0.656