Detailed information NTG0789645

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: PUW49_RS01025
• Genome accession: NZ_CP118054
• Coordinates: 189148..190101 (+)
• Length: 317 a.a.
• NCBI ID: WP_024053125.1
• Uniprot ID: A0A412PLM5
• Organism: Streptococcus anginosus strain VSI37
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 184148..195101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW49_RS00985 (PUW49_00985)	-	185041..185406 (+)	366	WP_024053131.1	DUF1033 family protein	-
PUW49_RS00990 (PUW49_00990)	comYA	185476..186417 (+)	942	WP_024053130.1	competence type IV pilus ATPase ComGA	Machinery gene
PUW49_RS00995 (PUW49_00995)	comYB	186359..187381 (+)	1023	WP_274994772.1	competence type IV pilus assembly protein ComGB	Machinery gene
PUW49_RS01000 (PUW49_01000)	comYC	187378..187695 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
PUW49_RS01005 (PUW49_01005)	comYD	187685..188083 (+)	399	WP_022525973.1	competence type IV pilus minor pilin ComGD	Machinery gene
PUW49_RS01010 (PUW49_01010)	comGE/cglE	188055..188348 (+)	294	WP_024053127.1	competence type IV pilus minor pilin ComGE	Machinery gene
PUW49_RS01015 (PUW49_01015)	comGF/cglF	188332..188769 (+)	438	WP_024053126.1	competence type IV pilus minor pilin ComGF	Machinery gene
PUW49_RS01020 (PUW49_01020)	comGG	188750..189076 (+)	327	WP_257360478.1	competence type IV pilus minor pilin ComGG	-
PUW49_RS01025 (PUW49_01025)	comYH	189148..190101 (+)	954	WP_024053125.1	class I SAM-dependent methyltransferase	Machinery gene
PUW49_RS01030 (PUW49_01030)	-	190148..191347 (+)	1200	WP_024053124.1	acetate kinase	-
PUW49_RS01035 (PUW49_01035)	glmS	191742..193556 (+)	1815	WP_024053123.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35821.57 Da
• Isoelectric Point: 4.2900

>NTDB_id=789645 PUW49_RS01025 WP_024053125.1 189148..190101(+) (comYH) [Streptococcus anginosus strain VSI37]
MNFEKIEQAYTLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDSIAARYEVASTQDHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKKWLQKHAQIVAMIALPESLFGNAAYAKTIFVLKKQDEQAVQPFVYALSDLQNQADLLTFSEKFQNWSQESEI

Nucleotide

• Length: 954 bp

>NTDB_id=789645 PUW49_RS01025 WP_024053125.1 189148..190101(+) (comYH) [Streptococcus anginosus strain VSI37]
ATGAATTTTGAAAAAATTGAACAGGCCTATACGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAACAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGGCTGGAATTGGACGATCTGTTAATTGATATATCAGCCAGTATCGCAGATGTGATGGACGCAAAA
GTTAGTTTTGTGCAAGGTGACGCAGTACGCCCGCAAGTATTGAAAGAAAGCGATGTGATTATTAGCGATTTACCAGTTGG
CTTTTATCCTGATGATAGCATTGCGGCGCGCTATGAAGTGGCTAGTACACAGGATCATACCTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTATTGAAGAAATGGCTACAAAAGCATGCACAAATAGTTGCAATGATTGCGTTACCAGAGTCTCTTTTTGGAAA
TGCAGCATACGCTAAAACAATTTTTGTACTGAAAAAGCAAGATGAACAAGCTGTCCAACCATTTGTTTATGCTTTATCTG
ATTTGCAGAATCAAGCGGATTTATTGACATTTAGCGAAAAGTTTCAAAATTGGAGCCAAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-294)

3D structure

• AlphaFold DB: A0A412PLM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.905	99.369	0.615
comYH	Streptococcus mutans UA159	61.587	99.369	0.612