Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7649_RS10185 Genome accession   NZ_CP131630
Coordinates   1932922..1936035 (+) Length   1037 a.a.
NCBI ID   WP_341986380.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 2018C07-301     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1927922..1941035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7649_RS10165 (Q7649_10220) - 1928464..1928913 (-) 450 WP_003692085.1 CopD family copper resistance protein -
  Q7649_RS10170 (Q7649_10225) waaA 1928954..1930225 (-) 1272 WP_106158882.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  Q7649_RS10175 (Q7649_10230) gnd 1930288..1931736 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  Q7649_RS10180 (Q7649_10235) - 1931816..1932079 (-) 264 WP_017147189.1 hypothetical protein -
  Q7649_RS10185 (Q7649_10240) pilC 1932922..1936035 (+) 3114 WP_341986380.1 PilC family type IV pilus tip adhesin Machinery gene
  Q7649_RS10190 (Q7649_10245) - 1936687..1936971 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  Q7649_RS10195 (Q7649_10250) yccS 1937451..1939601 (-) 2151 WP_003699137.1 YccS family putative transporter -
  Q7649_RS10200 (Q7649_10255) pilU 1939718..1940944 (-) 1227 WP_003697786.1 PilT/PilU family type 4a pilus ATPase Machinery gene

Sequence

Protein


Download         Length: 1037 a.a.        Molecular weight: 113067.54 Da        Isoelectric Point: 9.9664

>NTDB_id=789643 Q7649_RS10185 WP_341986380.1 1932922..1936035(+) (pilC) [Neisseria gonorrhoeae strain 2018C07-301]
MNKTLKRRVFRHTALYTAILMFSHTGGGGGQAQARDYAIIMNGRNQPEVKSNVPSSIKDKDRKRTFSHTSQTNWRGQQNN
FISFDNSDELVSQQSGTAVFGTATYLPPYGKVSGFDTDRLKKRNNAVDWIRTTRIALAGYSYEGVVCRSGTGCPKLVYKT
RFSFDNPDLVKNAGKLDRYTDLSRENSPIYKLKDYPWLGVSFNLSSENTVKDSKLSNKLISSFSESNNNQTIVSTTEDHP
ISLGGSQREHTAVAYYLNAKLHLLDKKGIGDIAPGKTVRLGLLKPSIDVRKGNTGLSGILSFNATWDIKDTGQIPVKLGL
PEVKAGRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSLKPLS
ENEIKSKEPRFNGRQTVIRLDSGVQLIKLNGSKDEVVIFGNNGNNGTFGIVKEANVNLEADEWKKVLLPWTVRGPDNDNK
FKLINQKPDRYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKTGTDERSYNLKLSYIPGTMERKDIEG
NDSDLAKELRTFAEKGYVGDRYGVDGGFVLRQVNLNGQDRVFMFGAMGLGGRGAYALDLSKINEKYPAAAPLFDVKNGDK
NGKNGKNRVEVELGYTVGTPQIGKIRNGKYAAFLASGYAAKQIASQENKTALYVYDLKDTLGTPIAKIEVKGGKGGLSSP
TLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSNPDKWSVSTIFEGGKPITSAPAVSRLADKRVVIFGTGSDLSEEDVVGKD
QQYIYGIFDDDKGTGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSNGKGWVVRLREGERVTVKPIVVLRTAFV
TIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPEANTAVAQYSGHKKTAGGKSVPIGCMWKNSKTVCPNGYVYDK
PVNVRYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3114 bp        

>NTDB_id=789643 Q7649_RS10185 WP_341986380.1 1932922..1936035(+) (pilC) [Neisseria gonorrhoeae strain 2018C07-301]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAAGCCCGTGACTACGCTATTATCATGAACGGGCGAAACCAGCCCGAGGTAAAGTCGAATGTGC
CATCTTCAATAAAGGACAAAGACAGGAAGCGGACATTTAGCCATACGAGCCAGACAAACTGGCGGGGCCAACAAAACAAT
TTTATCTCATTCGACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCC
GCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAAAGCGCAACAATGCCGTTGATTGGATTCGTACCACCC
GCATCGCGCTGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACC
CGATTTTCCTTCGATAATCCCGACTTGGTAAAAAATGCGGGCAAGCTGGATAGGTACACAGACCTAAGCCGCGAAAATTC
GCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGAGCAGCGAGAATACCGTCAAAGATAGCA
AATTATCCAACAAATTGATATCTTCTTTTAGTGAAAGCAATAATAATCAAACCATCGTCTCTACGACAGAAGATCACCCT
ATTTCCCTTGGCGGCTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAA
AGGGATTGGAGATATCGCGCCAGGCAAAACAGTGCGGTTGGGTCTCTTGAAGCCGAGCATCGATGTGCGGAAAGGAAATA
CGGGGCTTAGCGGCATTCTATCTTTTAATGCTACGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTCGGCCTG
CCGGAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAGCCCTTTCGCCGGCACTGACCGCCCC
CGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGA
GCAGCAAAATTTTCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTCAAACCCTTGAGT
GAGAATGAGATTAAAAGTAAAGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGGATAGCGGCGTACAGCTGAT
CAAACTGAATGGAAGCAAGGATGAGGTCGTCATTTTTGGAAACAACGGCAACAACGGCACTTTCGGCATTGTTAAGGAAG
CGAACGTCAATCTTGAAGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGATAATGACAATAAA
TTTAAATTAATTAACCAAAAACCAGACAGATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGGCGA
CATCGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAA
AAACCGGCACGGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGC
AATGACTCCGACCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGG
CTTTGTCTTGCGTCAAGTTAACTTAAACGGACAAGACCGCGTGTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCG
CATACGCCTTGGATTTAAGCAAAATCAACGAAAAGTATCCAGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAAA
AACGGCAAAAACGGCAAAAATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAA
CGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATG
TGTATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGGCGGCAAAGGCGGGCTTTCGTCCCCC
ACGCTGGTGGATAAAGATTTGGACGGCACAGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGA
TTTGAGCGATTCCAATCCTGATAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCG
TTTCCCGACTGGCAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTAAGGAT
CAACAATATATTTACGGTATCTTTGACGACGATAAGGGGACGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGG
CGGGCTGCTCGAGCAAACGCTTACGAAGGAAAATAACACCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGAACG
GCAAAGGGTGGGTAGTGAGATTGAGGGAAGGAGAACGCGTTACCGTCAAACCGATTGTGGTATTGCGTACCGCCTTTGTC
ACCATCCGTAGCTATACGGGTAATGACAAATGCGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGC
ATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCACAATATTCCGGCCATAAGAAAACCG
CCGGCGGCAAGTCCGTCCCCATAGGCTGCATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAG
CCGGTTAATGTGCGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGG
TATAGACCCCGCCGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACG
ATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(505-847)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.038

100

0.733