Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   PUW62_RS02595 Genome accession   NZ_CP118046
Coordinates   523447..525303 (+) Length   618 a.a.
NCBI ID   WP_274997438.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI52     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 518447..530303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW62_RS02580 (PUW62_02580) fmt 520435..521370 (+) 936 WP_274997337.1 methionyl-tRNA formyltransferase -
  PUW62_RS02585 (PUW62_02585) rsmB 521360..522673 (+) 1314 WP_274997339.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  PUW62_RS02590 (PUW62_02590) - 522692..523432 (+) 741 WP_022526377.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  PUW62_RS02595 (PUW62_02595) stkP 523447..525303 (+) 1857 WP_274997438.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PUW62_RS02600 (PUW62_02600) liaF 525564..526262 (+) 699 WP_024052107.1 cell wall-active antibiotics response protein LiaF -
  PUW62_RS02605 (PUW62_02605) - 526259..527254 (+) 996 WP_024052106.1 sensor histidine kinase -
  PUW62_RS02610 (PUW62_02610) - 527256..527888 (+) 633 WP_024052105.1 response regulator transcription factor -
  PUW62_RS02615 (PUW62_02615) - 527928..529328 (+) 1401 WP_024052104.1 Cof-type HAD-IIB family hydrolase -
  PUW62_RS02620 (PUW62_02620) - 529330..529701 (+) 372 WP_024052103.1 S1 RNA-binding domain-containing protein -
  PUW62_RS02625 (PUW62_02625) - 529835..530152 (-) 318 WP_024052102.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 618 a.a.        Molecular weight: 67091.00 Da        Isoelectric Point: 9.3344

>NTDB_id=789457 PUW62_RS02595 WP_274997438.1 523447..525303(+) (stkP) [Streptococcus anginosus strain VSI52]
MFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEEGQQ
YLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVAFAETSL
TQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENPNVPQALENV
VIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKPTPAPTKEAVSSKPTPK
PKAKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVKKDSVIR
TNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTPAAGSTY
DLTSKTRITLKVAKSVSSVTMPSYISSTYEFAYNNLTEVIGIQGANIEKRSITTAPTGTQANTIIRQTPEAGQSLNLKSD
RIVLYVYEPKTEDSSTSESSSQSDSSSDKTSPSSSSSSASGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1857 bp        

>NTDB_id=789457 PUW62_RS02595 WP_274997438.1 523447..525303(+) (stkP) [Streptococcus anginosus strain VSI52]
ATATTTGCCGGACGATATAGAATCATCAAACAAATTGGCCGAGGAGGTATGGCAGATGTCTACTTGGCGAAAGACTTGAT
TTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAATTACCAGACAGATCCGATTGCTGTAGCACGTTTTCAAA
GAGAAGCACGCGCCATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGAGAAGAAGAAGGCCAGCAG
TATTTAGCAATGGAATATGTGGCTGGACTTGACTTAAAACGCTATATCAAAGAGCATGCTCCTTTGTCTAATGAAGAAGC
GGTTCGAATCATGGGACAAATCCTTTTAGCGATGCGTTTGGCGCACACGCATGGGATTGTTCACCGTGATTTGAAACCTC
AAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTCACTGACTTTGGAATTGCGGTAGCTTTTGCAGAAACGAGTTTA
ACGCAAACCAACTCTATGTTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGTTCAAAAGCGACCGTTCAGAG
TGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGATGGAGATAGTGCTGTTACGA
TTGCCCTACAGCATTTCCAAAAGCCTCTACCGTCCATTATTGCTGAAAATCCAAACGTTCCACAGGCATTGGAAAATGTA
GTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGTGGATTTATCAAGCTGTTT
ATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACGGCTAAGGCAGACACAAAGACACTGCCGAAAGTGT
CACAAAATACTTTGACTTCTGCGACGAAGCCAACACCTGCTCCCACAAAAGAAGCAGTCAGTAGTAAACCTACGCCTAAG
CCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACACGCTATAAAGTTTTGTTATCAGCAGTGGTTTTAGTTATCGCAGCTCT
GGTGGCTTTGGTCTATTTGAGTCCATCAAATGTAAAAATTCCAGATGTTACTGGAAAAACTATTGCCCAAGCACGTTCTG
CAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAAAAAGATTCAGTCATTCGC
ACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAAAGGGACTAAAACTTTTAT
TATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCCATCAACAATCTGGTACAAAAATACAAGGTTTCAAAAGGTTTAA
TTAAAACAGAAGAAGTTGAGAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCAGCAGCAGGCAGCACTTAT
GATTTGACTTCAAAGACCCGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGATGCCAAGCTATATCAGTTC
AACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTGAAAAACGTTCGATTACAA
CAGCTCCAACGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAGTCTTTGAATTTGAAGAGTGAT
CGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTCACAATCTGATAGCAGCTC
AGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAGCTAGTGGTAATGATGGGAGCAGCTCAAAAACACCAGACACAAGTG
CTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(499-567)

PASTA domain (PASTA)

(358-421)

PASTA domain (PASTA)

(427-494)

Protein kinase domain (Pkinase)

(6-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.523

94.337

0.618
  stkP Streptococcus pneumoniae D39

65.18

94.337

0.615
  stkP Streptococcus pneumoniae R6

65.18

94.337

0.615
  stkP Streptococcus pneumoniae Rx1

65.009

94.337

0.613
  pknB Streptococcus mutans UA159

58.031

93.689

0.544
  stkP/pknB Streptococcus salivarius strain HSISS4

55.236

95.793

0.529