NTDB

Overview

Name	comA	Type	Regulator
Locus tag	Q6385_RS00650	Genome accession	NZ_CP130893
Coordinates	137844..138125 (+)	Length	93 a.a.
NCBI ID	WP_003696701.1	Uniprot ID	A0A0H4IVZ5
Organism	Neisseria gonorrhoeae strain NJ1914646
Function	processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 132844..143125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q6385_RS00605 (Q6385_00605)	-	132950..134104 (+)	1155	WP_010359759.1	cupin domain-containing protein	-
Q6385_RS00610 (Q6385_00610)	-	134113..134339 (+)	227	Protein_119	hypothetical protein	-
Q6385_RS00615 (Q6385_00615)	-	134414..134686 (+)	273	WP_226888059.1	hypothetical protein	-
Q6385_RS00620 (Q6385_00620)	-	134747..136021 (+)	1275	WP_003698048.1	HlyD family secretion protein	-
Q6385_RS00625 (Q6385_00625)	-	136206..136553 (+)	348	WP_003687399.1	hypothetical protein	-
Q6385_RS00630 (Q6385_00630)	-	136567..136782 (+)	216	WP_003687400.1	hypothetical protein	-
Q6385_RS00635 (Q6385_00635)	-	136884..137435 (+)	552	Protein_124	cysteine peptidase family C39 domain-containing protein	-
Q6385_RS00640 (Q6385_00640)	-	137421..137651 (+)	231	WP_225577429.1	ATP-binding cassette domain-containing protein	-
Q6385_RS00645 (Q6385_00645)	-	137649..137765 (-)	117	Protein_126	IS5/IS1182 family transposase	-
Q6385_RS00650 (Q6385_00650)	comA	137844..138125 (+)	282	WP_003696701.1	ATP-binding cassette domain-containing protein	Regulator
Q6385_RS00655 (Q6385_00655)	-	138146..139372 (-)	1227	WP_003690589.1	YihY family inner membrane protein	-
Q6385_RS00660 (Q6385_00660)	-	139471..139676 (+)	206	Protein_129	NAD(P)H-quinone oxidoreductase	-
Q6385_RS00665 (Q6385_00665)	queC	139861..140520 (+)	660	WP_003690590.1	7-cyano-7-deazaguanine synthase QueC	-
Q6385_RS00670 (Q6385_00670)	-	140548..141063 (+)	516	WP_003687408.1	DUF1543 domain-containing protein	-
Q6385_RS00675 (Q6385_00675)	queD	141151..141585 (+)	435	WP_003690591.1	6-carboxytetrahydropterin synthase QueD	-
Q6385_RS00680 (Q6385_00680)	-	141856..142224 (+)	369	WP_003690592.1	DUF1304 domain-containing protein	-
Q6385_RS00685 (Q6385_00685)	-	142221..142859 (+)	639	WP_103195245.1	7-carboxy-7-deazaguanine synthase QueE	-

Sequence

Protein

Download Length: 93 a.a. Molecular weight: 10117.78 Da Isoelectric Point: 6.4598

                                >NTDB_id=788198 Q6385_RS00650 WP_003696701.1 137844..138125(+) (comA) [Neisseria gonorrhoeae strain NJ1914646]

MIREEISAMPMGYETLIGDMGSALSGGQKQRIVLARALYCEPKILFLDEAASHLDIANEKAVNANLNGLSIIKIMAAHRK

ETVESADRKMSLG

Nucleotide

Download Length: 282 bp

                                >NTDB_id=788198 Q6385_RS00650 WP_003696701.1 137844..138125(+) (comA) [Neisseria gonorrhoeae strain NJ1914646]

ATGATTCGCGAAGAAATCTCCGCCATGCCTATGGGCTATGAAACCTTGATCGGCGATATGGGCAGCGCACTGTCAGGCGG

ACAAAAACAACGTATCGTATTGGCGCGGGCCTTATATTGCGAACCGAAAATCCTATTTTTAGATGAAGCGGCCAGTCATT

TGGATATTGCCAATGAAAAAGCAGTCAATGCAAACTTGAATGGCTTGTCTATTATAAAAATTATGGCGGCACACAGAAAG

GAAACGGTGGAATCAGCAGATAGGAAAATGTCTTTAGGATAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(14-51)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0H4IVZ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comA	Streptococcus mitis SK321	46.154	97.849	0.452
comA	Streptococcus mitis NCTC 12261	45.055	97.849	0.441
comA	Streptococcus pneumoniae TIGR4	45.055	97.849	0.441
comA	Streptococcus pneumoniae Rx1	45.055	97.849	0.441
comA	Streptococcus pneumoniae R6	45.055	97.849	0.441
comA	Streptococcus pneumoniae D39	45.055	97.849	0.441
comA/nlmT	Streptococcus mutans UA159	47.126	93.548	0.441
comA	Streptococcus gordonii str. Challis substr. CH1	43.956	97.849	0.43

Detailed information NTG0788198