Detailed information
Bioinformatically predicted
Overview
| Name | comA/nlmT | Type | Regulator |
| Locus tag | MGCS35823_RS02825 | Genome accession | NZ_CP117289 |
| Coordinates | 525552..527705 (-) | Length | 717 a.a. |
| NCBI ID | WP_084916306.1 | Uniprot ID | - |
| Organism | Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823 | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 495711..546531 | 525552..527705 | within | 0 |
Gene organization within MGE regions
Location: 495711..546531
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGCS35823_RS02660 (MGCS35823_01084) | - | 495810..498218 (+) | 2409 | WP_037590009.1 | DNA translocase FtsK | - |
| MGCS35823_RS02665 (MGCS35823_01086) | - | 498287..498640 (-) | 354 | WP_037587264.1 | DUF3397 domain-containing protein | - |
| MGCS35823_RS02670 (MGCS35823_01088) | rplK | 498883..499308 (+) | 426 | WP_003049875.1 | 50S ribosomal protein L11 | - |
| MGCS35823_RS02675 (MGCS35823_01090) | rplA | 499414..500103 (+) | 690 | WP_003049876.1 | 50S ribosomal protein L1 | - |
| MGCS35823_RS02680 | - | 500378..500512 (-) | 135 | WP_003054384.1 | hypothetical protein | - |
| MGCS35823_RS02685 (MGCS35823_01092) | - | 500606..500773 (-) | 168 | WP_003054374.1 | hypothetical protein | - |
| MGCS35823_RS02690 (MGCS35823_01094) | pyrH | 501055..501783 (+) | 729 | WP_003049878.1 | UMP kinase | - |
| MGCS35823_RS02695 (MGCS35823_01096) | frr | 501812..502369 (+) | 558 | WP_003054381.1 | ribosome recycling factor | - |
| MGCS35823_RS02700 (MGCS35823_01098) | - | 502478..503335 (+) | 858 | WP_003054345.1 | S1 RNA-binding domain-containing protein | - |
| MGCS35823_RS02705 (MGCS35823_01100) | msrA | 503408..503917 (+) | 510 | WP_003054395.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| MGCS35823_RS02710 (MGCS35823_01102) | - | 503914..504129 (+) | 216 | WP_003054340.1 | YozE family protein | - |
| MGCS35823_RS02715 (MGCS35823_01104) | - | 504289..505524 (+) | 1236 | WP_003054361.1 | LysM domain-containing protein | - |
| MGCS35823_RS02720 (MGCS35823_01106) | - | 505835..507607 (+) | 1773 | WP_003054339.1 | oleate hydratase | - |
| MGCS35823_RS02725 (MGCS35823_01108) | - | 507768..508829 (+) | 1062 | WP_003054347.1 | PhoH family protein | - |
| MGCS35823_RS02730 (MGCS35823_01110) | - | 508876..509451 (+) | 576 | WP_003054351.1 | uracil-DNA glycosylase family protein | - |
| MGCS35823_RS02735 (MGCS35823_01112) | ybeY | 509610..510107 (+) | 498 | WP_003054373.1 | rRNA maturation RNase YbeY | - |
| MGCS35823_RS02740 (MGCS35823_01114) | - | 510088..510495 (+) | 408 | WP_003054389.1 | diacylglycerol kinase | - |
| MGCS35823_RS02745 (MGCS35823_01116) | era | 510616..511512 (+) | 897 | WP_002985743.1 | GTPase Era | - |
| MGCS35823_RS02750 (MGCS35823_01118) | - | 511533..512009 (+) | 477 | WP_002993018.1 | NUDIX domain-containing protein | - |
| MGCS35823_RS02755 (MGCS35823_01120) | - | 512318..512569 (-) | 252 | WP_080589767.1 | hypothetical protein | - |
| MGCS35823_RS02760 | - | 512870..513088 (+) | 219 | WP_072135532.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| MGCS35823_RS02765 (MGCS35823_01124) | - | 513369..515082 (-) | 1714 | Protein_488 | peptide cleavage/export ABC transporter | - |
| MGCS35823_RS02770 (MGCS35823_01126) | - | 515380..515607 (+) | 228 | WP_022554332.1 | Blp family class II bacteriocin | - |
| MGCS35823_RS02775 (MGCS35823_01128) | - | 515656..515973 (+) | 318 | WP_002994587.1 | hypothetical protein | - |
| MGCS35823_RS02780 (MGCS35823_01130) | - | 516156..517177 (+) | 1022 | Protein_491 | IS3 family transposase | - |
| MGCS35823_RS02785 (MGCS35823_01132) | - | 517391..518809 (+) | 1419 | WP_231873805.1 | IS1182 family transposase | - |
| MGCS35823_RS02795 (MGCS35823_01136) | - | 520415..521165 (+) | 751 | Protein_494 | response regulator transcription factor | - |
| MGCS35823_RS02805 (MGCS35823_01140) | - | 521507..522640 (-) | 1134 | WP_275902597.1 | ISAs1-like element IS1548 family transposase | - |
| MGCS35823_RS02810 (MGCS35823_01142) | - | 523003..523827 (+) | 825 | WP_275910586.1 | GHKL domain-containing protein | - |
| MGCS35823_RS02815 (MGCS35823_01144) | - | 523975..524100 (-) | 126 | WP_011017462.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | - |
| MGCS35823_RS02820 (MGCS35823_01148) | - | 524177..525541 (-) | 1365 | WP_084916305.1 | bacteriocin secretion accessory protein | - |
| MGCS35823_RS02825 (MGCS35823_01150) | comA/nlmT | 525552..527705 (-) | 2154 | WP_084916306.1 | peptide cleavage/export ABC transporter | Regulator |
| MGCS35823_RS02830 (MGCS35823_01152) | - | 527992..528219 (+) | 228 | WP_002992018.1 | Blp family class II bacteriocin | - |
| MGCS35823_RS02835 (MGCS35823_01154) | - | 528232..528432 (+) | 201 | WP_003060803.1 | class IIb bacteriocin, lactobin A/cerein 7B family | - |
| MGCS35823_RS02840 (MGCS35823_01156) | - | 528726..528920 (+) | 195 | WP_002990768.1 | hypothetical protein | - |
| MGCS35823_RS02845 (MGCS35823_01158) | - | 528968..529249 (+) | 282 | WP_011054252.1 | hypothetical protein | - |
| MGCS35823_RS02850 (MGCS35823_01160) | - | 529443..529853 (+) | 411 | WP_275910587.1 | hypothetical protein | - |
| MGCS35823_RS02855 | - | 530100..530347 (+) | 248 | Protein_505 | hypothetical protein | - |
| MGCS35823_RS02860 (MGCS35823_01162) | - | 530369..530623 (+) | 255 | WP_014612089.1 | CPBP family intramembrane glutamic endopeptidase | - |
| MGCS35823_RS02865 (MGCS35823_01166) | - | 531035..531772 (+) | 738 | WP_228113938.1 | hypothetical protein | - |
| MGCS35823_RS02870 (MGCS35823_01168) | - | 531922..532864 (-) | 943 | Protein_508 | hypothetical protein | - |
| MGCS35823_RS02875 | shp2 | 532933..533001 (-) | 69 | WP_134771781.1 | peptide pheromone SHP2 | - |
| MGCS35823_RS02880 (MGCS35823_01170) | rgg2 | 533091..533945 (+) | 855 | Protein_510 | quorum-sensing system transcriptional regulator Rgg2 | - |
| MGCS35823_RS02885 (MGCS35823_01172) | mutM | 534127..534954 (+) | 828 | WP_084916308.1 | DNA-formamidopyrimidine glycosylase | - |
| MGCS35823_RS02890 (MGCS35823_01174) | coaE | 534933..535544 (+) | 612 | WP_172453883.1 | dephospho-CoA kinase | - |
| MGCS35823_RS02895 | - | 535559..535792 (-) | 234 | WP_159335598.1 | hypothetical protein | - |
| MGCS35823_RS02900 (MGCS35823_01176) | - | 535912..536613 (+) | 702 | WP_003056868.1 | ABC transporter ATP-binding protein | - |
| MGCS35823_RS02905 (MGCS35823_01178) | - | 536603..538240 (+) | 1638 | WP_022554345.1 | hypothetical protein | - |
| MGCS35823_RS02910 (MGCS35823_01180) | - | 538350..539852 (+) | 1503 | WP_084916309.1 | helicase HerA-like domain-containing protein | - |
| MGCS35823_RS02915 (MGCS35823_01182) | - | 540016..541233 (+) | 1218 | WP_223846048.1 | multidrug efflux MFS transporter | - |
| MGCS35823_RS02920 | rpmG | 541230..541376 (+) | 147 | WP_003047126.1 | 50S ribosomal protein L33 | - |
| MGCS35823_RS02925 (MGCS35823_01184) | secG | 541422..541658 (+) | 237 | WP_003047129.1 | preprotein translocase subunit SecG | - |
| MGCS35823_RS02930 (MGCS35823_01186) | rnr | 541755..544085 (+) | 2331 | WP_084916311.1 | ribonuclease R | - |
| MGCS35823_RS02935 (MGCS35823_01188) | smpB | 544088..544555 (+) | 468 | WP_022554349.1 | SsrA-binding protein SmpB | - |
| MGCS35823_RS02940 (MGCS35823_01190) | - | 544734..545090 (+) | 357 | WP_003053910.1 | hypothetical protein | - |
| MGCS35823_RS02945 (MGCS35823_01192) | - | 545183..546531 (+) | 1349 | WP_111678974.1 | IS3 family transposase | - |
Sequence
Protein
Download Length: 717 a.a. Molecular weight: 80504.46 Da Isoelectric Point: 7.1728
>NTDB_id=783436 MGCS35823_RS02825 WP_084916306.1 525552..527705(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVIYQNKKNYLIIGDPDSTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVGYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVIYQNKKNYLIIGDPDSTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVGYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS
Nucleotide
Download Length: 2154 bp
>NTDB_id=783436 MGCS35823_RS02825 WP_084916306.1 525552..527705(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCATCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACTCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGGCTATCTGGATAAATCCTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCATCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACTCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGGCTATCTGGATAAATCCTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA/nlmT | Streptococcus mutans UA159 |
72.448 |
99.721 |
0.722 |
| comA | Streptococcus mitis NCTC 12261 |
67.227 |
99.582 |
0.669 |
| comA | Streptococcus mitis SK321 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae Rx1 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae D39 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae R6 |
66.807 |
99.582 |
0.665 |
| comA | Streptococcus pneumoniae TIGR4 |
66.527 |
99.582 |
0.662 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
65.738 |
100 |
0.658 |