Detailed information NTG0783274

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: MGGS36055_RS05705
• Genome accession: NZ_CP117286
• Coordinates: 1104037..1104711 (-)
• Length: 224 a.a.
• NCBI ID: WP_003060678.1
• Uniprot ID: A0AAE9R380
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1099037..1109711

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGGS36055_RS05680 (MGGS36055_02286)	-	1099222..1100499 (-)	1278	WP_015017041.1	pyrimidine-nucleoside phosphorylase	-
MGGS36055_RS05685 (MGGS36055_02288)	-	1100486..1101085 (-)	600	WP_015057597.1	class I SAM-dependent methyltransferase	-
MGGS36055_RS05690 (MGGS36055_02290)	coaA	1101354..1102274 (+)	921	WP_110408128.1	type I pantothenate kinase	-
MGGS36055_RS05695 (MGGS36055_02292)	rpsT	1102328..1102576 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
MGGS36055_RS05700 (MGGS36055_02294)	ciaH	1102734..1104044 (-)	1311	WP_012766987.1	HAMP domain-containing sensor histidine kinase	Regulator
MGGS36055_RS05705 (MGGS36055_02296)	ciaR	1104037..1104711 (-)	675	WP_003060678.1	response regulator transcription factor	Regulator
MGGS36055_RS05710 (MGGS36055_02298)	-	1104915..1107452 (-)	2538	WP_003061495.1	M1 family metallopeptidase	-
MGGS36055_RS05715 (MGGS36055_02300)	phoU	1107653..1108306 (-)	654	WP_015017046.1	phosphate signaling complex protein PhoU	-
MGGS36055_RS05720 (MGGS36055_02302)	pstB	1108384..1109142 (-)	759	WP_003057749.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25601.58 Da
• Isoelectric Point: 4.4684

>NTDB_id=783274 MGGS36055_RS05705 WP_003060678.1 1104037..1104711(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide

• Length: 675 bp

>NTDB_id=783274 MGGS36055_RS05705 WP_003060678.1 1104037..1104711(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGCTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (5-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae D39	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae R6	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae TIGR4	84.615	98.661	0.835
ciaR	Streptococcus mutans UA159	84.163	98.661	0.83
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.326	100	0.388
vicR	Streptococcus mutans UA159	35.443	100	0.375