Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MGGS36055_RS01860 Genome accession   NZ_CP117286
Coordinates   348892..349653 (+) Length   253 a.a.
NCBI ID   WP_003059809.1    Uniprot ID   A0A9X5LVZ2
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 343892..354653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGGS36055_RS01845 (MGGS36055_00746) - 344151..345719 (-) 1569 WP_042357844.1 ABC transporter substrate-binding protein/permease -
  MGGS36055_RS01850 (MGGS36055_00748) - 345918..347843 (+) 1926 WP_015016681.1 DUF2207 domain-containing protein -
  MGGS36055_RS01855 (MGGS36055_00750) - 347909..348748 (+) 840 WP_012766572.1 undecaprenyl-diphosphate phosphatase -
  MGGS36055_RS01860 (MGGS36055_00752) mecA 348892..349653 (+) 762 WP_003059809.1 adaptor protein MecA Regulator
  MGGS36055_RS01865 (MGGS36055_00754) - 349660..350829 (+) 1170 WP_003054822.1 MraY family glycosyltransferase -
  MGGS36055_RS01870 (MGGS36055_00756) sufC 350941..351711 (+) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  MGGS36055_RS01875 (MGGS36055_00758) sufD 351808..353070 (+) 1263 WP_003054871.1 Fe-S cluster assembly protein SufD -
  MGGS36055_RS01880 (MGGS36055_00760) - 353101..354327 (+) 1227 WP_003062308.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29071.72 Da        Isoelectric Point: 4.0755

>NTDB_id=783250 MGGS36055_RS01860 WP_003059809.1 348892..349653(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPELLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=783250 MGGS36055_RS01860 WP_003059809.1 348892..349653(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGATAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
GGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCTGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACCAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTTTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482