Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   PO908_RS10140 Genome accession   NZ_CP117042
Coordinates   1965973..1967295 (-) Length   440 a.a.
NCBI ID   WP_394467990.1    Uniprot ID   -
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1960973..1972295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS10120 (PO908_10085) - 1962300..1964876 (+) 2577 WP_394467989.1 YfhO family protein -
  PO908_RS10135 (PO908_10100) comE 1965224..1965973 (-) 750 WP_022526721.1 competence system response regulator transcription factor ComE Regulator
  PO908_RS10140 (PO908_10105) comD/comD2 1965973..1967295 (-) 1323 WP_394467990.1 sensor histidine kinase Regulator
  PO908_RS10145 (PO908_10110) - 1967316..1967462 (-) 147 WP_003026814.1 bacteriocin -
  PO908_RS10155 (PO908_10120) rlmH 1967744..1968223 (-) 480 WP_041784074.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PO908_RS10160 (PO908_10125) htrA 1968417..1969607 (+) 1191 WP_021002247.1 S1C family serine protease Regulator
  PO908_RS10165 (PO908_10130) spo0J 1969662..1970429 (+) 768 WP_021002248.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51922.58 Da        Isoelectric Point: 8.7160

>NTDB_id=782277 PO908_RS10140 WP_394467990.1 1965973..1967295(-) (comD/comD2) [Streptococcus anginosus strain CGMH_KH1]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDFTTLIHYSIRYMMFFIQPSFFYLYFFKVKKVK
KHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLIFILKAIDYFKFNFKYFKKVDFKENIVQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYN
EIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVIRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=782277 PO908_RS10140 WP_394467990.1 1965973..1967295(-) (comD/comD2) [Streptococcus anginosus strain CGMH_KH1]
GTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTCAACTGATTTCACTACTTTAATAC
ATTATTCCATTAGATATATGATGTTTTTTATTCAACCATCATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAAA
AAACACCTTTCTGTATTTTTAGCATTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGGTTGTTCTATATTTTTATCAATATTATTTCTTTAATTTTTA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGTGGATTTCAAAGAGAATATTGTGCAGTTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTGTCGCATTGGCTTAGCAACATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAAAAAGAGCGAGAACAACTACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTATAAT
GAAATTCGAGGCTTTCGTCATGATTATGGCGGAATGTTGGCAAGCTTCCAATCGGCCATTCATACAGGTGATATAAAAGA
AGTAGAGCGAATTTATCAGGAAGTGCTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTCAAACCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAATAA
TGCAATAGAGGGAGCGGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTAGTAGATCTGGATACAGAAACAATCTTAG
TTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGTGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATAAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.545
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

58.901

86.818

0.511
  comD Streptococcus mitis SK321

46.684

89.091

0.416
  comD Streptococcus mitis NCTC 12261

48.404

85.455

0.414
  comD/comD2 Streptococcus pneumoniae TIGR4

47.872

85.455

0.409
  comD/comD1 Streptococcus pneumoniae Rx1

47.34

85.455

0.405
  comD/comD1 Streptococcus pneumoniae D39

47.34

85.455

0.405
  comD/comD1 Streptococcus pneumoniae R6

47.34

85.455

0.405