Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PO908_RS02010 Genome accession   NZ_CP117042
Coordinates   377441..378193 (+) Length   250 a.a.
NCBI ID   WP_021001304.1    Uniprot ID   A0AAP6BPK5
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 372441..383193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS01995 (PO908_01995) csm5 372791..373885 (+) 1095 WP_070836495.1 type III-A CRISPR-associated RAMP protein Csm5 -
  PO908_RS02000 (PO908_02000) csm6 373882..375039 (+) 1158 WP_022527056.1 type III-A CRISPR-associated CARF protein Csm6 -
  PO908_RS02005 (PO908_02005) csm6 375049..376329 (+) 1281 WP_084740928.1 type III-A CRISPR-associated CARF protein Csm6 -
  PO908_RS02010 (PO908_02010) mecA 377441..378193 (+) 753 WP_021001304.1 adaptor protein MecA Regulator
  PO908_RS02015 (PO908_02015) - 378184..379350 (+) 1167 WP_041783991.1 glycosyltransferase family 4 protein -
  PO908_RS02020 (PO908_02020) sufC 379443..380213 (+) 771 WP_394468123.1 Fe-S cluster assembly ATPase SufC -
  PO908_RS02025 (PO908_02025) sufD 380253..381515 (+) 1263 WP_204973263.1 Fe-S cluster assembly protein SufD -
  PO908_RS02030 (PO908_02030) - 381531..382763 (+) 1233 WP_394468017.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28968.80 Da        Isoelectric Point: 4.1287

>NTDB_id=782229 PO908_RS02010 WP_021001304.1 377441..378193(+) (mecA) [Streptococcus anginosus strain CGMH_KH1]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMESEENSDELTQKYIYYIL
KFSSLKEAIVFSKTVDYAVNTSELYKMDDHYYLTILVDIEGRPKRYPAWLLALMREHAEDTDVTRAVLQEHGYLLLVNEA
VASLQKVKCL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=782229 PO908_RS02010 WP_021001304.1 377441..378193(+) (mecA) [Streptococcus anginosus strain CGMH_KH1]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAGGATTTAGAGGAACGTGGGATGGAAAT
GGCAGATTTTCTAGTCCCACAAGAAAAAACAGAAGAGTTTTTCTATGCGATTTTAGATGAGTTGGAAATGCCAGAGAGCT
TTTTAGATAGCGGCATGCTCAGTTTTCGTGTGACACCAAAGCCCGACCGATTGGATGTCTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTCGATGATTTGGCAGATTTGCCAGATGTAGAAGAGCTGTCTCAAATGTCTCCTGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAGTCAGAGGAAAATAGTGACGAACTAACGCAGAAATATATTTATTACATTTTG
AAATTTTCTAGCCTGAAAGAAGCAATTGTTTTTTCTAAGACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAAAAT
GGACGACCACTATTATTTGACAATCTTGGTTGATATTGAAGGGCGTCCAAAGCGTTATCCAGCTTGGCTCCTGGCTTTGA
TGCGTGAGCATGCAGAGGATACGGATGTGACAAGAGCTGTTTTGCAAGAACACGGTTACTTATTGCTTGTCAACGAGGCG
GTTGCCAGTCTTCAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.397

98.8

0.656
  mecA Streptococcus pneumoniae D39

66.397

98.8

0.656
  mecA Streptococcus pneumoniae R6

66.397

98.8

0.656
  mecA Streptococcus pneumoniae TIGR4

65.992

98.8

0.652
  mecA Streptococcus mutans UA159

50.602

99.6

0.504
  mecA Streptococcus thermophilus LMD-9

45.882

100

0.468
  mecA Streptococcus thermophilus LMG 18311

45.49

100

0.464