Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   M0P28_RS02510 Genome accession   NZ_CP116958
Coordinates   457666..459546 (+) Length   626 a.a.
NCBI ID   WP_117479652.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP074     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 452666..464546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P28_RS02495 (M0P28_02495) fmt 454644..455579 (+) 936 WP_069789206.1 methionyl-tRNA formyltransferase -
  M0P28_RS02500 (M0P28_02500) rsmB 455569..456891 (+) 1323 WP_069789205.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M0P28_RS02505 (M0P28_02505) - 456929..457666 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M0P28_RS02510 (M0P28_02510) pknB 457666..459546 (+) 1881 WP_117479652.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M0P28_RS02515 (M0P28_02515) liaF 459641..460336 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  M0P28_RS02520 (M0P28_02520) - 460333..461358 (+) 1026 WP_117479650.1 sensor histidine kinase -
  M0P28_RS02525 (M0P28_02525) - 461342..461986 (+) 645 WP_013851527.1 response regulator transcription factor -
  M0P28_RS02530 (M0P28_02530) - 462104..463504 (+) 1401 WP_069789204.1 Cof-type HAD-IIB family hydrolase -
  M0P28_RS02535 (M0P28_02535) - 463504..463860 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 67951.21 Da        Isoelectric Point: 5.1472

>NTDB_id=781681 M0P28_RS02510 WP_117479652.1 457666..459546(+) (pknB) [Streptococcus pasteurianus strain WUSP074]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KVATENQATKAKTKKKKSRRMFGTLMKIFFAVVIVAITIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVATESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSRGYVQVSSPSST
ATITAQTPYYGETLSGNVILYLAADEEESSQAPSSSSSEPSESKESSSSSSSTDDSSSSTESSNEQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=781681 M0P28_RS02510 WP_117479652.1 457666..459546(+) (pknB) [Streptococcus pasteurianus strain WUSP074]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTGGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGATCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGGATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGATGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCTATCATTGATGAGAATAAGAATGTTCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGTAGCAACAGAAAACCAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTACTATCTTTACTTACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTACGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATCAGTCAAACGCCTAGTGAAGGTGAAACCTTTAAGGTAAGTGGTGATGATAAGATTACCTTTAAAGTAGCCAC
AGAAAGTACAGTGACAATGCCGAATTTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTAACAGCTCTAGGCGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTAGGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTATCACTGCTCAAACACCTTACTATGGTGAAACGTTAAGTGGTAACGTGATACTTTACCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCGCCATCGTCATCAAGTTCAGAACCCTCTGAATCAAAAGAATCAAGTTCATCAAGTAGCAGTACAG
ATGATAGTAGCTCATCAACAGAATCAAGTAATGAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(511-575)

PASTA domain (PASTA)

(440-506)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.143

93.77

0.639
  stkP/pknB Streptococcus salivarius strain HSISS4

64.646

94.888

0.613
  stkP Streptococcus pneumoniae TIGR4

58.161

85.144

0.495
  stkP Streptococcus pneumoniae D39

57.974

85.144

0.494
  stkP Streptococcus pneumoniae R6

57.974

85.144

0.494
  stkP Streptococcus pneumoniae Rx1

57.786

85.144

0.492