Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   M0P24_RS08380 Genome accession   NZ_CP116957
Coordinates   1649236..1651116 (-) Length   626 a.a.
NCBI ID   WP_117508846.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP070     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1644236..1656116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P24_RS08355 (M0P24_08355) - 1644921..1645277 (-) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  M0P24_RS08360 (M0P24_08360) - 1645277..1646677 (-) 1401 WP_003063536.1 Cof-type HAD-IIB family hydrolase -
  M0P24_RS08365 (M0P24_08365) - 1646796..1647440 (-) 645 WP_013851527.1 response regulator transcription factor -
  M0P24_RS08370 (M0P24_08370) - 1647424..1648449 (-) 1026 WP_013851526.1 sensor histidine kinase -
  M0P24_RS08375 (M0P24_08375) liaF 1648446..1649141 (-) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  M0P24_RS08380 (M0P24_08380) pknB 1649236..1651116 (-) 1881 WP_117508846.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M0P24_RS08385 (M0P24_08385) - 1651116..1651853 (-) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M0P24_RS08390 (M0P24_08390) rsmB 1651891..1653213 (-) 1323 WP_048791289.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M0P24_RS08395 (M0P24_08395) fmt 1653203..1654138 (-) 936 WP_117508845.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 67847.05 Da        Isoelectric Point: 5.0689

>NTDB_id=781633 M0P24_RS08380 WP_117508846.1 1649236..1651116(-) (pknB) [Streptococcus pasteurianus strain WUSP070]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KVATENQATKAKTKKKKSHRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVATESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATITAQTPYYGETLSGNVILYLAADEEESSQAPSSSSSEPSESKESSSSSSSTDDSSSSTESSNEQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=781633 M0P24_RS08380 WP_117508846.1 1649236..1651116(-) (pknB) [Streptococcus pasteurianus strain WUSP070]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAGGTGGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGATCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGGATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGATGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAGAATGTTCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGTAGCAACAGAAAACCAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACATCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCCCCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTACGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATCAGTCAAACGCCTAGTGAAGGTGAAACCTTTAAGGTAAGTGGTGATGATAAGATTACCTTTAAAGTAGCCAC
AGAAAGTACAGTGACAATGCCGAATTTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTAACAGCTCTAGGCGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTATCACTGCTCAAACACCTTACTATGGTGAAACGTTAAGTGGTAACGTGATACTTTACCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCGCCATCGTCATCAAGTTCAGAACCCTCTGAATCAAAAGAATCAAGTTCATCAAGCAGCAGTACGG
ATGATAGTAGCTCATCAACAGAATCAAGTAATGAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-506)

PASTA domain (PASTA)

(511-575)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.313

93.77

0.641
  stkP/pknB Streptococcus salivarius strain HSISS4

64.646

94.888

0.613
  stkP Streptococcus pneumoniae TIGR4

54.966

93.291

0.513
  stkP Streptococcus pneumoniae D39

54.795

93.291

0.511
  stkP Streptococcus pneumoniae R6

54.795

93.291

0.511
  stkP Streptococcus pneumoniae Rx1

54.623

93.291

0.51