Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   QZH48_RS12110 Genome accession   NZ_CP129879
Coordinates   2464263..2466401 (-) Length   712 a.a.
NCBI ID   WP_146978299.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain CAB701     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2459263..2471401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QZH48_RS12090 (QZH48_12090) mreD 2460438..2460965 (-) 528 WP_012898708.1 rod shape-determining protein MreD -
  QZH48_RS12095 (QZH48_12095) mreC 2461056..2461931 (-) 876 WP_038602544.1 rod shape-determining protein MreC -
  QZH48_RS12100 (QZH48_12100) - 2462396..2462557 (-) 162 WP_186758664.1 hypothetical protein -
  QZH48_RS12105 (QZH48_12105) - 2462868..2464238 (-) 1371 WP_146978298.1 bacteriocin secretion accessory protein -
  QZH48_RS12110 (QZH48_12110) comA 2464263..2466401 (-) 2139 WP_146978299.1 peptide cleavage/export ABC transporter Regulator
  QZH48_RS12115 (QZH48_12115) - 2466837..2467025 (-) 189 WP_301675739.1 lactococcin G-beta family bacteriocin -
  QZH48_RS12120 (QZH48_12120) - 2467071..2467235 (-) 165 WP_146978301.1 enterocin 1071A family bacteriocin -
  QZH48_RS12125 (QZH48_12125) - 2468031..2468471 (+) 441 WP_146978302.1 NUDIX hydrolase -
  QZH48_RS12130 (QZH48_12130) rpiA 2468501..2469175 (-) 675 WP_301675740.1 ribose-5-phosphate isomerase RpiA -
  QZH48_RS12135 (QZH48_12135) - 2469259..2469945 (-) 687 WP_012898712.1 Crp/Fnr family transcriptional regulator -
  QZH48_RS12140 (QZH48_12140) - 2470028..2471248 (-) 1221 WP_029344587.1 MFS transporter -

Sequence

Protein


Download         Length: 712 a.a.        Molecular weight: 80216.36 Da        Isoelectric Point: 7.0866

>NTDB_id=781247 QZH48_RS12110 WP_146978299.1 2464263..2466401(-) (comA) [Lactococcus lactis subsp. lactis strain CAB701]
MKKIIYQQDEKDCGVACIAMILKHYGTEITIQRLRELSGTDLDGTSAFGIKKTFEKLGFDAPAFKAGDETWQEKDIPLPL
IAHIISEQKYQHYVVVYKVKGDEIWIADPAKGKIRKTISEFSKEWTGVLLFPKPKAEYKPSIERVDGLSSFIPILIKQKS
LIFHTALASLFITIFGIISSYYFQGLLDNIIPNQARSTLNILSIGLIFVYLFRVLFEYSRSYLLLLIGQRMSMSIMLDYF
KHVLSLPLSFFATRKSGEIISRFLDANKIIDALASATLSVILDFGMVILVGTTLAIQSTQLFLLTLAFLPFYILVVYVFI
RSYDKANTEEMSAGAEVNSSIIESLKGIETIKSYNGENHVYDRVDSEFVTLMKKSFKSVTLDNVQQSLKMVIELISSVLI
LWLGSSYVIDGKISLGQLITYNALLVFFTEPLQNIINLQVKMQKARVANKRLNEIMSISPEQRNTNINISKNIFSKDIKL
DKVSFSYNMKLPVLRDVSLEIYSKSKVALVGVSGSGKSTLAKLLVKFYDPSEGNITYGDINCQDIENHKLRNHVTYVPQE
SFFFNGTIIDNLTFGLSHQPEFEKILEACKAACLVDFINQQPLRFDSVLEEGGNNLSGGQKQRLAIARAILNDSEIIIFD
EATSGLDTLLEKEILEYLIKLQDKTIIFIAHHLSIAKACDEIIVLDQGILVGRGTHEELSEKEGVYRRLLNA

Nucleotide


Download         Length: 2139 bp        

>NTDB_id=781247 QZH48_RS12110 WP_146978299.1 2464263..2466401(-) (comA) [Lactococcus lactis subsp. lactis strain CAB701]
ATGAAAAAAATAATATATCAACAGGATGAAAAAGATTGTGGAGTAGCTTGTATAGCCATGATTTTAAAACATTATGGTAC
CGAAATTACTATTCAAAGGTTACGTGAACTTTCTGGGACAGATTTAGATGGCACGTCTGCTTTCGGAATAAAAAAAACAT
TTGAAAAATTAGGATTTGACGCACCAGCATTCAAAGCTGGTGATGAAACATGGCAAGAAAAAGATATACCCTTGCCTTTG
ATAGCTCACATAATAAGTGAACAAAAGTATCAACACTACGTGGTGGTTTATAAAGTTAAAGGTGATGAGATTTGGATTGC
TGATCCAGCAAAGGGAAAGATTAGAAAAACTATTTCTGAATTTTCTAAAGAGTGGACAGGTGTCTTACTTTTTCCTAAAC
CAAAAGCAGAATATAAACCGTCTATTGAAAGAGTAGATGGTTTATCTTCATTCATTCCTATACTAATAAAACAGAAGTCT
TTAATTTTTCATACTGCTTTAGCATCACTCTTCATCACGATTTTTGGAATCATAAGTTCTTACTATTTTCAAGGCTTATT
GGATAATATTATTCCAAATCAGGCTCGGTCGACTTTAAATATTCTTTCCATAGGACTTATTTTTGTTTATCTTTTTCGTG
TGCTTTTTGAATATAGTCGTAGCTATCTTCTACTTTTAATTGGGCAAAGAATGAGTATGAGCATAATGCTTGATTATTTT
AAACACGTTTTGTCACTACCTCTGAGTTTCTTTGCAACCAGAAAGTCAGGAGAAATTATTTCTCGCTTCTTGGATGCTAA
TAAAATTATTGATGCTCTTGCTAGTGCTACTTTATCTGTAATTCTGGATTTTGGAATGGTAATTCTGGTTGGCACAACAC
TTGCGATTCAAAGCACTCAGCTTTTTTTGCTCACCCTTGCCTTTCTACCTTTTTATATTTTGGTAGTATATGTGTTTATT
AGGAGTTACGATAAAGCAAATACAGAAGAAATGAGTGCAGGAGCTGAGGTTAATTCTAGCATTATTGAAAGTTTAAAAGG
AATTGAAACTATTAAGTCTTACAATGGAGAAAATCATGTCTATGATCGTGTAGATTCAGAATTTGTAACTTTAATGAAAA
AGTCTTTTAAATCGGTCACACTTGATAATGTACAACAGAGTTTAAAGATGGTTATTGAACTTATAAGTAGTGTATTGATA
CTATGGCTAGGGTCAAGTTATGTTATAGATGGAAAAATAAGTCTAGGACAATTAATTACTTATAATGCTTTACTTGTATT
TTTTACTGAGCCTTTACAAAATATTATTAATTTGCAAGTGAAAATGCAAAAAGCACGCGTAGCAAATAAACGTTTGAACG
AAATTATGTCAATATCTCCAGAACAAAGAAATACTAATATTAATATATCGAAAAATATATTTAGTAAGGATATAAAATTA
GATAAAGTAAGTTTTTCTTATAATATGAAGCTTCCCGTTTTAAGAGATGTTTCTTTAGAAATATACTCCAAAAGTAAGGT
TGCTCTTGTTGGTGTGAGTGGTTCAGGCAAGTCTACACTAGCTAAACTATTAGTAAAATTCTATGATCCCTCTGAGGGAA
ATATCACTTATGGTGATATAAATTGTCAAGATATTGAAAATCATAAATTAAGAAATCATGTTACTTATGTTCCTCAGGAA
TCTTTCTTTTTTAATGGCACAATTATAGATAATTTAACTTTTGGTCTTAGTCATCAACCAGAGTTTGAAAAAATTTTAGA
AGCATGTAAAGCTGCTTGTCTTGTTGATTTTATTAACCAACAACCTTTAAGATTTGATTCAGTTCTTGAAGAAGGAGGAA
ATAATCTATCAGGAGGACAAAAGCAACGCTTAGCAATAGCTAGAGCTATTTTAAATGATTCTGAAATAATTATTTTTGAT
GAAGCAACTAGTGGTCTTGATACCTTATTAGAAAAAGAGATTTTAGAATATTTAATTAAGTTACAGGATAAAACTATCAT
TTTTATTGCTCACCATCTATCAATAGCTAAAGCCTGTGATGAAATCATTGTTCTAGATCAAGGAATATTGGTTGGGAGAG
GAACACACGAGGAATTATCTGAAAAAGAGGGTGTATATAGGAGATTATTAAACGCATAA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(167-432)

Peptidase C39 family (Peptidase_C39)

(2-136)

ABC transporter (ABC_tran)

(494-644)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

46.893

99.438

0.466
  comA Streptococcus gordonii str. Challis substr. CH1

46.893

99.438

0.466
  comA Streptococcus pneumoniae D39

46.751

99.438

0.465
  comA Streptococcus pneumoniae R6

46.751

99.438

0.465
  comA Streptococcus pneumoniae TIGR4

46.751

99.438

0.465
  comA Streptococcus pneumoniae Rx1

46.751

99.438

0.465
  comA Streptococcus mitis SK321

46.328

99.438

0.461
  comA/nlmT Streptococcus mutans UA159

44.663

100

0.447