Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PHA78_RS10250 Genome accession   NZ_CP116604
Coordinates   2109932..2110654 (-) Length   240 a.a.
NCBI ID   WP_248038977.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2104932..2115654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS10230 - 2104969..2106195 (-) 1227 WP_161947177.1 cysteine desulfurase -
  PHA78_RS10235 sufD 2106197..2107459 (-) 1263 WP_024376583.1 Fe-S cluster assembly protein SufD -
  PHA78_RS10240 sufC 2107476..2108249 (-) 774 WP_024376584.1 Fe-S cluster assembly ATPase SufC -
  PHA78_RS10245 - 2108763..2109935 (-) 1173 WP_272158119.1 MraY family glycosyltransferase -
  PHA78_RS10250 mecA 2109932..2110654 (-) 723 WP_248038977.1 adaptor protein MecA Regulator
  PHA78_RS10255 - 2110782..2111621 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  PHA78_RS10260 - 2111744..2113309 (+) 1566 WP_172020106.1 ABC transporter substrate-binding protein/permease -
  PHA78_RS10265 - 2113302..2114045 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  PHA78_RS10270 - 2114172..2114381 (-) 210 WP_009910800.1 hypothetical protein -
  PHA78_RS10275 - 2114467..2115369 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28053.60 Da        Isoelectric Point: 4.0497

>NTDB_id=778786 PHA78_RS10250 WP_248038977.1 2109932..2110654(-) (mecA) [Streptococcus sp. HN38]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPDEFFKSLEQTVREKSTPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYLVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=778786 PHA78_RS10250 WP_248038977.1 2109932..2110654(-) (mecA) [Streptococcus sp. HN38]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCACACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCTAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTTTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCACTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

49.59

100

0.504
  mecA Streptococcus thermophilus LMD-9

47.083

100

0.471
  mecA Streptococcus thermophilus LMG 18311

46.667

100

0.467