Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   PHA78_RS02325 Genome accession   NZ_CP116604
Coordinates   469800..471794 (+) Length   664 a.a.
NCBI ID   WP_029176714.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 464800..476794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS02310 fmt 466787..467725 (+) 939 WP_029179613.1 methionyl-tRNA formyltransferase -
  PHA78_RS02315 rsmB 467712..469025 (+) 1314 WP_272158414.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  PHA78_RS02320 - 469063..469800 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  PHA78_RS02325 stkP 469800..471794 (+) 1995 WP_029176714.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PHA78_RS02330 liaF 472119..472778 (+) 660 WP_232503813.1 cell wall-active antibiotics response protein LiaF -
  PHA78_RS02335 - 472775..473791 (+) 1017 WP_004195187.1 sensor histidine kinase -
  PHA78_RS02340 - 473763..474404 (+) 642 WP_024398623.1 response regulator transcription factor -
  PHA78_RS02345 - 474454..475854 (+) 1401 WP_029173958.1 Cof-type HAD-IIB family hydrolase -
  PHA78_RS02350 - 475856..476227 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71389.96 Da        Isoelectric Point: 6.5352

>NTDB_id=778755 PHA78_RS02325 WP_029176714.1 469800..471794(+) (stkP) [Streptococcus sp. HN38]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGIVFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGR

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=778755 PHA78_RS02325 WP_029176714.1 469800..471794(+) (stkP) [Streptococcus sp. HN38]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTCGCT
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAGGCGACCATTCAAAGTGACATTTATGCGATGGGGATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCAAAACTCTCCCAGGCCAATGTTGAAACGAAAGTACCGCATACAAATAGTTCTGCCCAAGTTTCTGCGACGGAT
AAAGGGCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGAATCGTGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTGTCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTTGTCATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTATGTTTCCAAAGGAGTAGCGCCACAAGT
TGTGCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATACAGAGTTAACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAGCGCTAGGCGTCAATGTGGAAAGCATTGAAAAACAAGAAGATAGAAGCTATTACTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCGACCGGCACTAGTAGTGATTCCTCAACAGGAAGTTCCACCAGCACAAGTACTTCAACAGATAGCGGACGATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-240)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(574-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.086

97.59

0.518
  stkP Streptococcus pneumoniae D39

52.932

97.59

0.517
  stkP Streptococcus pneumoniae R6

52.932

97.59

0.517
  stkP Streptococcus pneumoniae Rx1

52.778

97.59

0.515
  stkP/pknB Streptococcus salivarius strain HSISS4

52.65

88.102

0.464
  pknB Streptococcus mutans UA159

55.083

81.476

0.449