Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PML98_RS01605 Genome accession   NZ_CP116581
Coordinates   357420..358703 (-) Length   427 a.a.
NCBI ID   WP_115235075.1    Uniprot ID   -
Organism   Enterococcus durans strain R59-1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 352420..363703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML98_RS01575 (PML98_01575) - 352468..353436 (-) 969 WP_113845206.1 glycosyltransferase family 2 protein -
  PML98_RS01580 (PML98_01580) - 353617..353967 (-) 351 WP_005875490.1 PepSY domain-containing protein -
  PML98_RS01585 (PML98_01585) pepA 354165..355244 (+) 1080 WP_016177292.1 glutamyl aminopeptidase -
  PML98_RS01590 (PML98_01590) - 355549..355869 (+) 321 WP_005875492.1 thioredoxin family protein -
  PML98_RS01595 (PML98_01595) - 355891..356358 (+) 468 WP_193809669.1 universal stress protein -
  PML98_RS01600 (PML98_01600) ytpR 356698..357315 (+) 618 WP_081133845.1 YtpR family tRNA-binding protein -
  PML98_RS01605 (PML98_01605) htrA 357420..358703 (-) 1284 WP_115235075.1 S1C family serine protease Regulator
  PML98_RS01610 (PML98_01610) rlmH 359131..359610 (+) 480 WP_005875496.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PML98_RS01615 (PML98_01615) - 359886..360794 (+) 909 WP_002332708.1 IS982-like element ISEfm1 family transposase -
  PML98_RS01620 (PML98_01620) - 360881..361735 (+) 855 WP_002331979.1 AraC family transcriptional regulator -

Sequence

Protein


Download         Length: 427 a.a.        Molecular weight: 44805.78 Da        Isoelectric Point: 4.5954

>NTDB_id=778571 PML98_RS01605 WP_115235075.1 357420..358703(-) (htrA) [Enterococcus durans strain R59-1]
MDRKDVTSKMKKKNNGLWRKLGLGLVGGVIGGLLTAGIFYAALGNGHSNTSTGGNQNSSGETVVENVKVNVDSDITSAVD
KVQDAVVSVINLQSQNQSNDFGKLFGQQQQSTEDSDLEASSEGSGVIYKKEGNTSYIVTNNHVVDGQQGLEVLLKDGTKV
KAELVGTDAYSDLAVLKIQSDKVDKVASFGDSSALKVGEPAIAIGSPLGSEYANSVTSGIVSSLNRQVTSTNESNETVNI
NAIQTDAAINPGNSGGPLINIEGQVIGINSSKIATTSESSSGVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMY
DLSYVSTQQKEQVLKIPSSVTNGVIVASVQPATPAEKAGLKQYDVITKIDDTEVSSGVELQSALYKKKVGDTVKITYYQE
KDEKTATVELTIDQSALKQNQSSNSGN

Nucleotide


Download         Length: 1284 bp        

>NTDB_id=778571 PML98_RS01605 WP_115235075.1 357420..358703(-) (htrA) [Enterococcus durans strain R59-1]
ATGGATAGAAAAGATGTGACATCAAAAATGAAAAAGAAAAATAATGGTCTTTGGCGCAAACTTGGACTAGGTTTAGTCGG
TGGTGTGATTGGAGGATTGTTAACAGCGGGTATTTTTTATGCTGCATTAGGAAATGGTCACTCCAATACGAGTACTGGGG
GTAACCAGAATTCGTCAGGTGAAACTGTTGTAGAAAATGTCAAAGTGAATGTAGATTCAGATATTACTAGTGCTGTAGAT
AAAGTACAAGATGCGGTAGTTTCCGTTATCAACTTGCAAAGTCAAAATCAATCGAACGATTTTGGCAAACTATTTGGGCA
ACAGCAGCAAAGTACTGAAGATAGTGATCTAGAGGCTTCTAGTGAAGGGAGTGGCGTGATCTACAAAAAAGAGGGCAATA
CTTCATATATCGTAACAAATAACCACGTAGTTGATGGGCAACAAGGATTAGAAGTTTTGCTCAAAGATGGGACAAAAGTC
AAAGCAGAATTAGTTGGAACTGATGCTTATTCTGATTTAGCTGTATTGAAGATCCAATCAGATAAAGTGGATAAAGTTGC
TTCTTTTGGCGACTCTAGTGCTTTAAAAGTTGGTGAACCTGCGATTGCAATTGGTTCTCCTTTAGGTTCCGAATATGCCA
ATTCAGTGACGTCAGGTATCGTTTCTTCTTTGAACCGACAAGTGACAAGTACAAATGAATCCAACGAAACTGTAAATATC
AATGCGATCCAAACAGATGCTGCAATCAATCCTGGTAACTCAGGTGGTCCACTGATCAACATTGAAGGACAAGTGATTGG
GATCAACTCAAGTAAAATCGCTACTACTTCTGAATCTTCATCTGGCGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAA
GTAATGATGTAGTCAATATCATCAACCAACTTGAAAAAGATGGTAAAGTGACACGTCCTGCATTAGGAATTACGATGTAC
GATTTATCTTATGTTTCAACGCAGCAAAAAGAACAAGTCTTGAAGATTCCTTCTTCAGTCACAAATGGTGTGATCGTGGC
AAGTGTCCAACCAGCAACACCTGCTGAAAAAGCTGGTTTGAAACAATATGATGTAATTACTAAAATCGACGACACAGAAG
TTTCATCTGGTGTTGAGTTGCAATCAGCTCTTTATAAGAAAAAAGTTGGTGACACAGTAAAAATCACTTATTACCAAGAA
AAAGATGAAAAAACTGCTACAGTTGAATTGACGATCGATCAATCTGCATTAAAACAAAACCAATCATCGAATTCAGGAAA
CTGA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(123-268)

PDZ domain (PDZ_2)

(313-410)

Peptidase family M50 (Peptidase_M50)

(7-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.333

94.848

0.506
  htrA Streptococcus mutans UA159

58.611

84.309

0.494
  htrA Streptococcus mitis NCTC 12261

53.866

90.867

0.489
  htrA Streptococcus pneumoniae TIGR4

59.763

79.157

0.473
  htrA Streptococcus pneumoniae R6

59.763

79.157

0.473
  htrA Streptococcus pneumoniae Rx1

59.763

79.157

0.473
  htrA Streptococcus pneumoniae D39

59.763

79.157

0.473