Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   QYH60_RS05385 Genome accession   NZ_CP129292
Coordinates   1003681..1005564 (+) Length   627 a.a.
NCBI ID   WP_058207874.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain KMGR2-43     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 998681..1010564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYH60_RS05355 (QYH60_05355) - 999795..1000037 (+) 243 WP_003131476.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  QYH60_RS05360 (QYH60_05360) amaP 1000065..1000625 (+) 561 WP_010906186.1 alkaline shock response membrane anchor protein AmaP -
  QYH60_RS05365 (QYH60_05365) - 1000636..1000824 (+) 189 WP_301401502.1 DUF2273 domain-containing protein -
  QYH60_RS05370 (QYH60_05370) - 1000845..1001351 (+) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  QYH60_RS05375 (QYH60_05375) rsmB 1001550..1002824 (+) 1275 WP_301401504.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QYH60_RS05380 (QYH60_05380) - 1002905..1003681 (+) 777 WP_003130802.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QYH60_RS05385 (QYH60_05385) pknB 1003681..1005564 (+) 1884 WP_058207874.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QYH60_RS05390 (QYH60_05390) rpsO 1005746..1006015 (+) 270 WP_010906184.1 30S ribosomal protein S15 -
  QYH60_RS05395 (QYH60_05395) proC 1006094..1006882 (-) 789 WP_012898440.1 pyrroline-5-carboxylate reductase -
  QYH60_RS05400 (QYH60_05400) glmU 1007110..1008486 (+) 1377 WP_003130798.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  QYH60_RS05405 (QYH60_05405) - 1008591..1009175 (+) 585 WP_012898439.1 NUDIX hydrolase -
  QYH60_RS05410 (QYH60_05410) macP 1009168..1009446 (+) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  QYH60_RS05415 (QYH60_05415) - 1009479..1010159 (+) 681 WP_012898438.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 67914.98 Da        Isoelectric Point: 4.6993

>NTDB_id=778177 QYH60_RS05385 WP_058207874.1 1003681..1005564(+) (pknB) [Lactococcus lactis subsp. lactis strain KMGR2-43]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVVNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLDQAKSKIKDAKLKVGTVHKQQSSTI
AEGNVIKTDPTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPTVGA
SVDPTQEIVITYSVYTAPSSSSTTSESTTTPETSSSTTSSTSSSTTSQPSTDNNNSSKESSTTSSSS

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=778177 QYH60_RS05385 WP_058207874.1 1003681..1005564(+) (pknB) [Lactococcus lactis subsp. lactis strain KMGR2-43]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATCAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGATCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGACCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGTAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CGCTTGACCAAGCAAAAAGCAAAATTAAAGATGCAAAACTAAAAGTGGGAACCGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAATGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATTTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCCGACGGTTATGTATATTCTGTTTATCCGACTGTTGGAGCG
TCCGTTGATCCAACTCAAGAAATTGTAATCACTTATAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACAACGACGCCTGAAACTTCGTCAAGCACAACTTCAAGTACTTCAAGTTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(506-573)

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(434-501)

Protein kinase domain (Pkinase)

(12-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

48.897

86.762

0.424
  stkP/pknB Streptococcus salivarius strain HSISS4

50.962

82.935

0.423
  stkP Streptococcus pneumoniae TIGR4

48.024

80.702

0.388
  stkP Streptococcus pneumoniae D39

47.826

80.702

0.386
  stkP Streptococcus pneumoniae R6

47.826

80.702

0.386
  stkP Streptococcus pneumoniae Rx1

47.628

80.702

0.384