Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PML95_RS02665 Genome accession   NZ_CP116507
Coordinates   524835..526091 (-) Length   418 a.a.
NCBI ID   WP_272163535.1    Uniprot ID   -
Organism   Vagococcus lutrae strain K204-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 519835..531091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML95_RS02645 (PML95_02645) walK 520017..521843 (+) 1827 WP_248848403.1 cell wall metabolism sensor histidine kinase WalK -
  PML95_RS02650 (PML95_02650) - 521840..523144 (+) 1305 WP_272163533.1 YycH family regulatory protein -
  PML95_RS02655 (PML95_02655) - 523144..523974 (+) 831 WP_248856533.1 two-component system regulatory protein YycI -
  PML95_RS02660 (PML95_02660) - 523992..524798 (+) 807 WP_272163534.1 MBL fold metallo-hydrolase -
  PML95_RS02665 (PML95_02665) htrA 524835..526091 (-) 1257 WP_272163535.1 S1C family serine protease Regulator
  PML95_RS02670 (PML95_02670) rlmH 526428..526907 (+) 480 WP_272163536.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PML95_RS02675 (PML95_02675) - 526947..527867 (+) 921 WP_126762839.1 abortive infection family protein -
  PML95_RS02680 (PML95_02680) yghU 528303..529088 (+) 786 WP_126762837.1 glutathione-dependent disulfide-bond oxidoreductase -
  PML95_RS02685 (PML95_02685) - 529285..529758 (-) 474 WP_126762835.1 nucleoside deaminase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44365.71 Da        Isoelectric Point: 4.4561

>NTDB_id=777700 PML95_RS02665 WP_272163535.1 524835..526091(-) (htrA) [Vagococcus lutrae strain K204-1]
MKTYETSTSSPLKRFGTGLLGGLIGGAVAFGLLFNFNQDSDKTSQPLNNHGEATKVEKVAYDVENNTSKAVEKVQGAVVS
VINLQKRQEMADEYGLGGLFGLPQQPEKKSEDNQDELETSSEGSGVIYKKDGKNAYVVTNNHVVEGSDALEVLMNDGSKV
SAELVGADAYTDLAVLKISAEGVKDTAEFGDSDVLKIGEPAIAIGSPLGSDYANSVTQGIISAKNRTITNQNPETGQPTN
INAIQTDAAINPGNSGGPLINIAGQVIGINSIKIARAASGISAEGMGFSIPSNDVVDIINQLEQNGQVIRPMLGVTMIDL
AVISQEQQEKILKLPTDIKSGVIIRSVQAASPAEAAGLKQYDVIVGIDGKEIENATDLQTILYTKKVGDEIEVTYYREHH
KNTVKVSLSLDRSSLEKE

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=777700 PML95_RS02665 WP_272163535.1 524835..526091(-) (htrA) [Vagococcus lutrae strain K204-1]
ATGAAAACATATGAAACATCTACTTCATCCCCTCTTAAACGTTTTGGAACGGGACTTTTAGGCGGACTCATTGGAGGTGC
CGTCGCGTTTGGTCTTTTATTTAATTTCAATCAAGACAGTGATAAGACATCTCAGCCATTAAACAATCATGGTGAAGCTA
CGAAAGTTGAGAAAGTGGCTTATGATGTGGAAAACAATACTTCTAAAGCCGTGGAGAAAGTACAAGGCGCTGTCGTTTCT
GTCATTAATTTACAAAAACGACAAGAAATGGCGGATGAATATGGACTAGGTGGACTATTCGGTTTACCGCAACAACCCGA
AAAGAAATCAGAAGATAATCAAGACGAGCTCGAAACTTCTAGCGAGGGCAGTGGGGTTATTTATAAAAAAGATGGTAAAA
ACGCCTATGTTGTGACTAATAATCACGTCGTGGAAGGTTCTGATGCTTTAGAAGTTTTAATGAACGACGGTTCAAAAGTG
TCCGCTGAACTAGTTGGTGCCGACGCTTATACTGATTTGGCTGTTTTAAAAATCAGTGCCGAGGGCGTAAAAGATACTGC
TGAATTTGGTGATTCTGATGTTCTAAAAATTGGTGAACCTGCGATTGCGATTGGTTCTCCACTCGGTTCTGATTATGCTA
ACTCTGTGACACAGGGTATCATTTCCGCTAAAAACCGAACGATCACGAATCAAAATCCAGAAACAGGACAACCTACGAAT
ATTAATGCCATTCAAACAGATGCGGCGATTAATCCTGGGAACTCTGGTGGACCATTAATTAATATTGCGGGCCAAGTAAT
CGGAATTAACTCCATTAAGATTGCACGAGCAGCGAGTGGTATCTCTGCTGAGGGTATGGGCTTCTCTATTCCAAGTAATG
ATGTTGTCGATATTATTAATCAACTAGAACAAAACGGACAAGTCATTCGCCCAATGTTAGGTGTGACGATGATTGATTTA
GCGGTCATTAGCCAAGAACAACAAGAAAAAATCTTAAAATTACCAACAGATATTAAATCTGGTGTAATCATTCGTAGCGT
TCAGGCCGCTTCTCCTGCTGAAGCAGCAGGCTTAAAACAGTATGATGTGATTGTGGGAATTGATGGTAAAGAGATTGAAA
ATGCGACTGACCTTCAAACCATTCTATATACGAAAAAAGTCGGGGACGAGATTGAGGTAACCTACTATCGTGAGCATCAC
AAAAATACCGTGAAAGTTTCCCTTTCATTAGACCGTTCTTCTTTAGAAAAAGAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(78-408)

Trypsin-like peptidase domain (Trypsin_2)

(123-269)

PDZ domain (PDZ_2)

(312-408)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.163

88.038

0.486
  htrA Streptococcus gordonii str. Challis substr. CH1

47.88

95.933

0.459
  htrA Streptococcus mitis NCTC 12261

49.081

91.148

0.447
  htrA Streptococcus pneumoniae TIGR4

50.139

86.364

0.433
  htrA Streptococcus pneumoniae D39

50.139

86.364

0.433
  htrA Streptococcus pneumoniae Rx1

50.139

86.364

0.433
  htrA Streptococcus pneumoniae R6

50.139

86.364

0.433