Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PML89_RS05025 Genome accession   NZ_CP116503
Coordinates   1072438..1073694 (+) Length   418 a.a.
NCBI ID   WP_252999564.1    Uniprot ID   -
Organism   Vagococcus lutrae strain K136-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1067438..1078694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML89_RS05000 (PML89_05000) - 1067941..1068453 (+) 513 WP_272157918.1 PRD domain-containing protein -
  PML89_RS05005 (PML89_05005) - 1068519..1069094 (+) 576 WP_252999560.1 PTS sugar transporter subunit IIA -
  PML89_RS05010 (PML89_05010) - 1069554..1069808 (-) 255 WP_252999561.1 hypothetical protein -
  PML89_RS05015 (PML89_05015) - 1070010..1071518 (-) 1509 WP_252999562.1 hypothetical protein -
  PML89_RS05020 (PML89_05020) rlmH 1071621..1072100 (-) 480 WP_252999563.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PML89_RS05025 (PML89_05025) htrA 1072438..1073694 (+) 1257 WP_252999564.1 S1C family serine protease Regulator
  PML89_RS05030 (PML89_05030) - 1073731..1074537 (-) 807 WP_126762855.1 MBL fold metallo-hydrolase -
  PML89_RS05035 (PML89_05035) - 1074555..1075385 (-) 831 WP_126762857.1 two-component system regulatory protein YycI -
  PML89_RS05040 (PML89_05040) - 1075385..1076689 (-) 1305 WP_252999565.1 YycH family regulatory protein -
  PML89_RS05045 (PML89_05045) walK 1076686..1078512 (-) 1827 WP_126762861.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44364.73 Da        Isoelectric Point: 4.4880

>NTDB_id=777668 PML89_RS05025 WP_252999564.1 1072438..1073694(+) (htrA) [Vagococcus lutrae strain K136-2]
MKTYETSTSSPLKRFGTGLLGGLIGGAVAFGLLFNFNQDSDKTSQPLNNHGEATKVEKVAYDVENNTSKAVEKVQGAVVS
VINLQKRQEMADEYGLGGLFGLPQQPEKKSENNQDELETSSEGSGVIYKKDGKNAYVVTNNHVVEGSDALEVLMNDGSKV
SAELVGADAYTDLAVLKISAEGVKDTAEFGDSDVLKIGEPAIAIGSPLGSDYANSVTQGIISAKNRTITNQNPETGQPTN
INAIQTDAAINPGNSGGPLINIAGQVIGINSIKIARAASGISAEGMGFSIPSNDVVDIINQLEQNGQVIRPMLGVTMIDL
AVISQEQQEKILKLPTDIKSGVIIRSVQAASPAEAAGLKQYDVIVGIDGKEIENATDLQTILYTKKVGDEIEVTYYREHH
KNTVKVSLSLDRSSLEKE

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=777668 PML89_RS05025 WP_252999564.1 1072438..1073694(+) (htrA) [Vagococcus lutrae strain K136-2]
ATGAAAACATATGAAACATCTACTTCATCCCCTCTTAAACGTTTTGGAACGGGACTTTTAGGCGGACTCATTGGAGGTGC
CGTCGCGTTTGGTCTTTTATTTAATTTCAATCAAGACAGTGATAAGACATCTCAGCCATTAAACAATCATGGTGAAGCTA
CGAAAGTTGAGAAGGTGGCTTATGATGTGGAAAACAATACTTCTAAAGCCGTGGAGAAAGTACAAGGCGCTGTCGTTTCT
GTCATTAATTTACAAAAACGACAAGAAATGGCGGATGAGTATGGACTAGGTGGACTATTCGGTTTACCGCAACAACCCGA
AAAGAAATCAGAAAATAATCAAGACGAGCTCGAAACTTCTAGCGAGGGCAGTGGGGTTATTTATAAAAAAGATGGTAAAA
ACGCCTATGTTGTGACTAATAATCACGTCGTGGAAGGCTCTGATGCTTTAGAAGTTTTAATGAACGACGGTTCAAAAGTG
TCCGCTGAACTAGTTGGTGCCGACGCTTATACTGATTTGGCTGTTTTAAAAATCAGTGCCGAGGGCGTAAAAGATACTGC
TGAATTTGGTGATTCTGATGTTCTAAAAATTGGTGAACCTGCGATTGCGATTGGTTCTCCACTCGGTTCTGATTATGCTA
ACTCTGTGACACAGGGTATCATTTCCGCTAAAAACCGAACGATCACGAATCAAAATCCAGAAACAGGCCAACCTACGAAT
ATTAATGCCATTCAAACAGATGCGGCGATTAATCCTGGGAACTCTGGTGGGCCATTAATTAATATTGCGGGCCAAGTAAT
CGGAATTAACTCTATTAAGATTGCGCGAGCAGCGAGTGGTATCTCTGCCGAGGGGATGGGCTTCTCTATTCCAAGTAATG
ATGTTGTCGATATTATTAATCAACTAGAACAAAATGGACAAGTCATTCGCCCAATGTTAGGTGTGACGATGATTGATTTA
GCGGTCATTAGCCAAGAACAACAAGAAAAAATCTTAAAATTACCAACAGATATTAAATCTGGTGTAATCATTCGTAGCGT
TCAGGCCGCTTCTCCTGCTGAAGCAGCAGGCTTAAAACAGTATGATGTGATTGTAGGAATTGATGGTAAAGAGATTGAAA
ATGCGACTGACCTTCAAACCATTCTATATACGAAAAAAGTCGGGGACGAGATTGAGGTAACCTACTATCGTGAGCACCAC
AAAAATACCGTGAAAGTTTCCCTTTCACTAGACCGTTCTTCTTTAGAAAAAGAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(79-408)

PDZ domain (PDZ_2)

(312-408)

Trypsin-like peptidase domain (Trypsin_2)

(123-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.163

88.038

0.486
  htrA Streptococcus gordonii str. Challis substr. CH1

48.379

95.933

0.464
  htrA Streptococcus mitis NCTC 12261

49.081

91.148

0.447
  htrA Streptococcus pneumoniae TIGR4

50.139

86.364

0.433
  htrA Streptococcus pneumoniae D39

50.139

86.364

0.433
  htrA Streptococcus pneumoniae Rx1

50.139

86.364

0.433
  htrA Streptococcus pneumoniae R6

50.139

86.364

0.433