Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PFZ59_RS05230 Genome accession   NZ_CP116393
Coordinates   1013488..1014210 (+) Length   240 a.a.
NCBI ID   WP_277697660.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1008488..1019210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS05205 (PFZ59_05205) - 1008772..1009674 (+) 903 WP_277697657.1 SPFH domain-containing protein -
  PFZ59_RS05210 (PFZ59_05210) - 1009760..1009969 (+) 210 WP_009910800.1 hypothetical protein -
  PFZ59_RS05215 (PFZ59_05215) - 1010096..1010839 (-) 744 WP_136647726.1 amino acid ABC transporter ATP-binding protein -
  PFZ59_RS05220 (PFZ59_05220) - 1010832..1012397 (-) 1566 WP_277697658.1 ABC transporter substrate-binding protein/permease -
  PFZ59_RS05225 (PFZ59_05225) - 1012524..1013360 (+) 837 WP_277697659.1 undecaprenyl-diphosphate phosphatase -
  PFZ59_RS05230 (PFZ59_05230) mecA 1013488..1014210 (+) 723 WP_277697660.1 adaptor protein MecA Regulator
  PFZ59_RS05235 (PFZ59_05235) - 1014207..1015379 (+) 1173 WP_221864831.1 MraY family glycosyltransferase -
  PFZ59_RS05240 (PFZ59_05240) sufC 1015782..1016555 (+) 774 WP_277697661.1 Fe-S cluster assembly ATPase SufC -
  PFZ59_RS05245 (PFZ59_05245) sufD 1016572..1017834 (+) 1263 WP_277697662.1 Fe-S cluster assembly protein SufD -
  PFZ59_RS05250 (PFZ59_05250) - 1017838..1019061 (+) 1224 WP_277697663.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28057.63 Da        Isoelectric Point: 4.0533

>NTDB_id=777092 PFZ59_RS05230 WP_277697660.1 1013488..1014210(+) (mecA) [Streptococcus suis strain SS/UPM/MY/F001]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
EQSLNFDEFTDLSELGDIASMTPDEFFKSLEQTVRERSAPDATAVRHLEEVEQEEEVDEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=777092 PFZ59_RS05230 WP_277697660.1 1013488..1014210(+) (mecA) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GAACAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATATCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGCTTGGAGCAAACCGTTCGTGAGAGAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGTAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGACCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

50.82

100

0.517
  mecA Streptococcus pneumoniae D39

50.82

100

0.517
  mecA Streptococcus pneumoniae R6

50.82

100

0.517
  mecA Streptococcus pneumoniae TIGR4

50.82

100

0.517
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.917

100

0.479
  mecA Streptococcus thermophilus LMG 18311

47.5

100

0.475