Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   PFZ59_RS00125 Genome accession   NZ_CP116393
Coordinates   16382..18376 (-) Length   664 a.a.
NCBI ID   WP_208581462.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 11382..23376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS00100 (PFZ59_00100) - 11950..12321 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  PFZ59_RS00105 (PFZ59_00105) - 12323..13723 (-) 1401 WP_208582434.1 Cof-type HAD-IIB family hydrolase -
  PFZ59_RS00110 (PFZ59_00110) - 13773..14414 (-) 642 WP_015646507.1 response regulator transcription factor -
  PFZ59_RS00115 (PFZ59_00115) - 14386..15402 (-) 1017 WP_208582432.1 sensor histidine kinase -
  PFZ59_RS00120 (PFZ59_00120) liaF 15399..16058 (-) 660 WP_226317727.1 cell wall-active antibiotics response protein LiaF -
  PFZ59_RS00125 (PFZ59_00125) stkP 16382..18376 (-) 1995 WP_208581462.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PFZ59_RS00130 (PFZ59_00130) - 18376..19113 (-) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  PFZ59_RS00135 (PFZ59_00135) rsmB 19151..20464 (-) 1314 WP_277697218.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  PFZ59_RS00140 (PFZ59_00140) fmt 20451..21389 (-) 939 WP_277697219.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71351.84 Da        Isoelectric Point: 6.3011

>NTDB_id=777068 PFZ59_RS00125 WP_208581462.1 16382..18376(-) (stkP) [Streptococcus suis strain SS/UPM/MY/F001]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGSGKKEVAKSGNKPVSKPRSGVRTRYKVLIGAILLTVIAAGLIFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGVKITLYVSKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=777068 PFZ59_RS00125 WP_208581462.1 16382..18376(-) (stkP) [Streptococcus suis strain SS/UPM/MY/F001]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGC
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCTACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATTGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCTTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCCCTATCCATGGATCGTCGGAATGAACCTAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCAAAACTCTCCCAGGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGTCAGGTGTGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATATTTTTCAACACTCCACGAACAGTTACCG
TTCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGTGAAAAAGTTGCCCAAGGTCTCGTCATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGTAAAAATTACCCTTTACGTTTCCAAAGGAGTAGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAGCACTGGGTGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGCGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGTACCAGTAGCGATTCCTCAACAGGAAGTTCCACTAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(574-638)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.241

97.59

0.52
  stkP Streptococcus pneumoniae D39

53.086

97.59

0.518
  stkP Streptococcus pneumoniae R6

53.086

97.59

0.518
  stkP Streptococcus pneumoniae Rx1

52.932

97.59

0.517
  stkP/pknB Streptococcus salivarius strain HSISS4

51.338

90.06

0.462
  pknB Streptococcus mutans UA159

55.083

81.476

0.449