Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | H7R41_RS13285 | Genome accession | NZ_AP022238 |
| Coordinates | 2816871..2817989 (+) | Length | 372 a.a. |
| NCBI ID | WP_114150255.1 | Uniprot ID | - |
| Organism | Acinetobacter baumannii strain WP8-W18-ESBL-11 | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2776587..2829346 | 2816871..2817989 | within | 0 |
Gene organization within MGE regions
Location: 2776587..2829346
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R41_RS13110 (WP8W18E11_25790) | brxC | 2778553..2782233 (-) | 3681 | WP_182925313.1 | BREX system P-loop protein BrxC | - |
| H7R41_RS13115 (WP8W18E11_25800) | - | 2782273..2782848 (-) | 576 | WP_002010699.1 | DUF1788 domain-containing protein | - |
| H7R41_RS13120 (WP8W18E11_25810) | - | 2782865..2783476 (-) | 612 | WP_182925314.1 | DUF1819 family protein | - |
| H7R41_RS13125 (WP8W18E11_25820) | - | 2783487..2784353 (-) | 867 | WP_182925315.1 | YafY family protein | - |
| H7R41_RS13130 (WP8W18E11_25830) | - | 2784474..2785493 (-) | 1020 | WP_182925316.1 | HNH endonuclease domain-containing protein | - |
| H7R41_RS13135 (WP8W18E11_25840) | - | 2785486..2786070 (-) | 585 | WP_182925317.1 | bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG | - |
| H7R41_RS13140 (WP8W18E11_25850) | - | 2786140..2786370 (-) | 231 | WP_182925318.1 | AlpA family transcriptional regulator | - |
| H7R41_RS13145 (WP8W18E11_25860) | - | 2786463..2787356 (-) | 894 | WP_182925319.1 | hydrolase or metal-binding protein | - |
| H7R41_RS13150 (WP8W18E11_25870) | - | 2787470..2788513 (-) | 1044 | WP_182925320.1 | YqaJ viral recombinase family protein | - |
| H7R41_RS13155 (WP8W18E11_25880) | - | 2788595..2788810 (-) | 216 | WP_182925321.1 | hypothetical protein | - |
| H7R41_RS13160 (WP8W18E11_25890) | - | 2788908..2789942 (-) | 1035 | WP_182925420.1 | DUF932 domain-containing protein | - |
| H7R41_RS13165 (WP8W18E11_25900) | - | 2790017..2790322 (-) | 306 | WP_182925421.1 | hypothetical protein | - |
| H7R41_RS13170 (WP8W18E11_25910) | - | 2790441..2790821 (-) | 381 | WP_182925322.1 | hypothetical protein | - |
| H7R41_RS13175 (WP8W18E11_25920) | - | 2790833..2791402 (-) | 570 | WP_182925323.1 | hypothetical protein | - |
| H7R41_RS13180 (WP8W18E11_25930) | - | 2791420..2791680 (-) | 261 | WP_182925324.1 | hypothetical protein | - |
| H7R41_RS13185 (WP8W18E11_25940) | - | 2792274..2793236 (-) | 963 | WP_182925325.1 | hypothetical protein | - |
| H7R41_RS13190 (WP8W18E11_25950) | - | 2793319..2794296 (-) | 978 | WP_227552539.1 | inovirus-type Gp2 protein | - |
| H7R41_RS13195 (WP8W18E11_25960) | - | 2794785..2796284 (-) | 1500 | WP_182925326.1 | hypothetical protein | - |
| H7R41_RS13200 (WP8W18E11_25970) | - | 2796415..2797116 (+) | 702 | WP_182925327.1 | hypothetical protein | - |
| H7R41_RS13205 (WP8W18E11_25980) | - | 2797126..2798268 (-) | 1143 | WP_180183011.1 | phage integrase central domain-containing protein | - |
| H7R41_RS13215 (WP8W18E11_25990) | ggt | 2798976..2800961 (-) | 1986 | WP_005135733.1 | gamma-glutamyltransferase | - |
| H7R41_RS13220 (WP8W18E11_26000) | - | 2801265..2802788 (-) | 1524 | WP_000857089.1 | DHA2 family efflux MFS transporter permease subunit | - |
| H7R41_RS13225 (WP8W18E11_26010) | - | 2802795..2803946 (-) | 1152 | WP_000128703.1 | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | - |
| H7R41_RS13230 (WP8W18E11_26020) | - | 2804216..2804713 (-) | 498 | WP_005135734.1 | thioesterase family protein | - |
| H7R41_RS13235 (WP8W18E11_26030) | hemB | 2804856..2805869 (+) | 1014 | WP_000222569.1 | porphobilinogen synthase | - |
| H7R41_RS13240 (WP8W18E11_26040) | - | 2805895..2807010 (+) | 1116 | WP_000546689.1 | FAD-binding oxidoreductase | - |
| H7R41_RS13245 (WP8W18E11_26050) | - | 2807002..2807907 (-) | 906 | WP_001039371.1 | TIGR01777 family oxidoreductase | - |
| H7R41_RS13250 (WP8W18E11_26060) | - | 2807996..2808448 (-) | 453 | WP_000164153.1 | ABZJ_00895 family protein | - |
| H7R41_RS13255 (WP8W18E11_26070) | - | 2808828..2809205 (+) | 378 | WP_001059437.1 | VOC family protein | - |
| H7R41_RS13260 (WP8W18E11_26080) | - | 2809273..2809746 (-) | 474 | WP_000152335.1 | OsmC family protein | - |
| H7R41_RS13265 (WP8W18E11_26090) | - | 2809911..2811179 (+) | 1269 | WP_002042946.1 | exonuclease SbcCD subunit D | - |
| H7R41_RS13270 (WP8W18E11_26100) | - | 2811189..2814785 (+) | 3597 | WP_000698794.1 | SbcC/MukB-like Walker B domain-containing protein | - |
| H7R41_RS13275 (WP8W18E11_26110) | - | 2814987..2815679 (-) | 693 | WP_001108509.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| H7R41_RS13280 (WP8W18E11_26120) | pilT | 2815806..2816843 (+) | 1038 | WP_000355489.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| H7R41_RS13285 (WP8W18E11_26130) | pilU | 2816871..2817989 (+) | 1119 | WP_114150255.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| H7R41_RS13290 (WP8W18E11_26140) | fur | 2818059..2818496 (-) | 438 | WP_001122847.1 | ferric iron uptake transcriptional regulator | - |
| H7R41_RS13295 (WP8W18E11_26150) | - | 2818608..2819006 (+) | 399 | WP_001170994.1 | outer membrane protein assembly factor BamE | - |
| H7R41_RS13300 (WP8W18E11_26160) | - | 2819061..2819384 (-) | 324 | WP_000442590.1 | RnfH family protein | - |
| H7R41_RS13305 (WP8W18E11_26170) | - | 2819384..2820451 (-) | 1068 | WP_004748097.1 | hypothetical protein | - |
| H7R41_RS13310 (WP8W18E11_26180) | - | 2820604..2821059 (-) | 456 | WP_000782976.1 | bacteriohemerythrin | - |
| H7R41_RS13315 (WP8W18E11_26190) | - | 2821312..2822160 (-) | 849 | WP_000336554.1 | class II glutamine amidotransferase | - |
| H7R41_RS13320 (WP8W18E11_26200) | - | 2822269..2823051 (-) | 783 | WP_000890283.1 | GNAT family N-acetyltransferase | - |
| H7R41_RS13325 (WP8W18E11_26210) | argB | 2823172..2824080 (-) | 909 | WP_001135419.1 | acetylglutamate kinase | - |
| H7R41_RS13330 (WP8W18E11_26220) | - | 2824095..2825513 (-) | 1419 | WP_001102843.1 | phosphomannomutase/phosphoglucomutase | - |
| H7R41_RS13335 (WP8W18E11_26230) | dut | 2825713..2826165 (-) | 453 | WP_000868152.1 | dUTP diphosphatase | - |
| H7R41_RS13340 (WP8W18E11_26240) | rep | 2826191..2828230 (-) | 2040 | WP_000093035.1 | DNA helicase Rep | - |
| H7R41_RS13345 (WP8W18E11_26250) | - | 2828424..2829077 (-) | 654 | WP_001202415.1 | OmpA family protein | - |
Sequence
Protein
Download Length: 372 a.a. Molecular weight: 41913.14 Da Isoelectric Point: 6.8715
>NTDB_id=77312 H7R41_RS13285 WP_114150255.1 2816871..2817989(+) (pilU) [Acinetobacter baumannii strain WP8-W18-ESBL-11]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFADTRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIHDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFADTRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIHDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
Nucleotide
Download Length: 1119 bp
>NTDB_id=77312 H7R41_RS13285 WP_114150255.1 2816871..2817989(+) (pilU) [Acinetobacter baumannii strain WP8-W18-ESBL-11]
ATGGATTTTAATGACCTACTCAACCTGATGGTTGAAAAGAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAACAGCCTTTCTGGGGAAGTAATTGGTCAACTGTTACATTCCA
TTATGAGTGAAAAACAACGCAAAGAATTTGCAGACACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCAGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TCATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGTGGCATTATTATTTTCGTAGGTGCGACAG
GTACAGGTAAATCTACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGATCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAGGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCAGATGAAGGTCCTGATCAATTATCAGACGGAAAACAGCATTTAACTTTTGACCGCCAGTAA
ATGGATTTTAATGACCTACTCAACCTGATGGTTGAAAAGAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAACAGCCTTTCTGGGGAAGTAATTGGTCAACTGTTACATTCCA
TTATGAGTGAAAAACAACGCAAAGAATTTGCAGACACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCAGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TCATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGTGGCATTATTATTTTCGTAGGTGCGACAG
GTACAGGTAAATCTACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGATCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAGGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCAGATGAAGGTCCTGATCAATTATCAGACGGAAAACAGCATTTAACTTTTGACCGCCAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
75.397 |
100 |
0.766 |
| pilU | Pseudomonas stutzeri DSM 10701 |
69.022 |
98.925 |
0.683 |
| pilU | Vibrio cholerae strain A1552 |
53.243 |
99.462 |
0.53 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
41.908 |
93.011 |
0.39 |