Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   QQA22_RS02155 Genome accession   NZ_CP126952
Coordinates   459138..460376 (+) Length   412 a.a.
NCBI ID   WP_072039460.1    Uniprot ID   -
Organism   Escherichia coli O78:H4 strain APEC E12049     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 454138..465376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA22_RS02130 (QQA22_02130) mrcA 454418..456970 (-) 2553 WP_001296475.1 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA -
  QQA22_RS02135 (QQA22_02135) hofM 457090..457869 (+) 780 WP_001318076.1 DNA utilization protein HofM -
  QQA22_RS02140 (QQA22_02140) hofN 457869..458408 (+) 540 WP_039004995.1 DNA utilization protein HofN -
  QQA22_RS02145 (QQA22_02145) hofO 458392..458832 (+) 441 WP_000367371.1 DNA utilization protein HofO -
  QQA22_RS02150 (QQA22_02150) hofP 458822..459226 (+) 405 WP_001318075.1 DNA utilization protein HofP -
  QQA22_RS02155 (QQA22_02155) comE 459138..460376 (+) 1239 WP_072039460.1 DNA uptake porin HofQ Machinery gene
  QQA22_RS02160 (QQA22_02160) aroK 460777..461298 (+) 522 WP_000818618.1 shikimate kinase AroK -
  QQA22_RS02165 (QQA22_02165) aroB 461355..462443 (+) 1089 WP_000439851.1 3-dehydroquinate synthase -
  QQA22_RS02170 (QQA22_02170) damX 462535..463821 (+) 1287 WP_000343222.1 cell division protein DamX -
  QQA22_RS02175 (QQA22_02175) dam 463928..464764 (+) 837 WP_000742141.1 adenine-specific DNA-methyltransferase -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 44714.26 Da        Isoelectric Point: 6.3191

>NTDB_id=769327 QQA22_RS02155 WP_072039460.1 459138..460376(+) (comE) [Escherichia coli O78:H4 strain APEC E12049]
MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGL
ITRQEGNILSVHSVAWQNDNIARQEAEQTRAQANLPLEKRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
KAALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTALGSDLSVATATTHVGFNIGRIN
GRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKL
HISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERREL
VVFITPRLVSSE

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=769327 QQA22_RS02155 WP_072039460.1 459138..460376(+) (comE) [Escherichia coli O78:H4 strain APEC E12049]
ATGAAGCAATGGATAGCCGCACTACTGTTGATGCTGATACCCGGCGTACAGGCGGCAAAGCCGCAAAAAGTGACGCTGAT
GGTGGATGACGTTCCGGTGGCTCAGGTGTTGCAGGCGCTGGCTGAACAGGAGAAGTTGAACCTGGTGGTTTCGCCAGACG
TCAGCGGTACGGTGTCGTTACATTTAACTGACGTTCCCTGGAAGCAGGCACTACAAACTGTAGTGAAAAGCGCCGGATTG
ATAACGCGCCAGGAGGGCAACATTCTCTCGGTGCATTCCGTTGCCTGGCAGAATGACAATATCGCCCGCCAGGAGGCGGA
GCAGACGCGGGCGCAGGCAAATCTGCCGCTGGAAAAACGCAATATTACTCTGCAATACGCCGACGCCGGAGAGCTGGCGA
AAGCGGGGGAGAAGCTACTGAGTGCCAAAGGGAGTATGACCGTCGATAAACGCACCAATCGCCTTTTGCTGCGAGATAAC
AAAGCGGCGTTAAGCGCGCTTGAACAGTGGGTAGCGCAAATGGATCTGCCGGTCGGGCAGGTTGAGCTGTCGGCGCATAT
TGTCACCATTAATGAAAAAAGTTTGCGTGAGTTAGGTGTGAAATGGACGCTGGCTGATGCGCAACACGCTGGTGGCGTTG
GGCAAGTCACCGCGCTTGGTAGCGACCTCTCCGTAGCGACGGCGACAACGCATGTCGGTTTTAACATTGGACGCATCAAC
GGACGTTTACTGGATCTTGAGCTTTCCGCGCTCGAACAAAAACAGCAGTTGGATATTATCGCCAGTCCGCGTCTGCTGGC
CTCACATCTTCAGCCTGCCAGCATTAAACAGGGGAGCGAAATTCCATATCAGGTTTCCAGCGGGGAAAGTGGCGCGACGT
CGGTGGAATTTAAAGAGGCCGTCCTGGGGATGGAAGTTACGCCCACGGTGTTACAAAAAGGTCGCATCCGGCTGAAATTA
CACATCAGCCAGAACGTTCCGGGGCAGGTGCTACAGCAGGCCGATGGCGAAGTGTTGGCGATTGATAAGCAGGAGATCGA
AACGCAGGTCGAGGTCAAAAGCGGAGAAACGTTGGCGCTGGGCGGCATTTTTACCCGTAAAAATAAATCGGGTCAGGATA
GCGTACCGTTGCTTGGTGACATTCCCTGGTTCGGGCAATTATTTCGTCATGACGGAAAAGAAGATGAACGACGCGAGTTA
GTGGTGTTTATCACGCCACGACTGGTTTCCAGTGAGTAA

Domains

Predicted by InterProScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(122-179)

Bacterial type II and III secretion system protein (Secretin)

(250-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

37.757

100

0.4
  comE Haemophilus influenzae Rd KW20

37.615

100

0.398
  pilQ Vibrio campbellii strain DS40M4

38.242

100

0.391
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

37.53

100

0.376
  pilQ Vibrio cholerae strain A1552

37.53

100

0.376
  comE Glaesserella parasuis strain SC1401

36.19

100

0.369
  pilQ Pseudomonas aeruginosa PAK

34.475

100

0.367