Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   O6R09_RS02105 Genome accession   NZ_CP114883
Coordinates   385910..387850 (+) Length   646 a.a.
NCBI ID   WP_235280521.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 380910..392850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS02090 (O6R09_02090) fmt 382888..383823 (+) 936 WP_269725720.1 methionyl-tRNA formyltransferase -
  O6R09_RS02095 (O6R09_02095) rsmB 383813..385135 (+) 1323 WP_154454641.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  O6R09_RS02100 (O6R09_02100) - 385173..385910 (+) 738 WP_269725721.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  O6R09_RS02105 (O6R09_02105) pknB 385910..387850 (+) 1941 WP_235280521.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  O6R09_RS02110 (O6R09_02110) liaF 387993..388685 (+) 693 WP_154454638.1 cell wall-active antibiotics response protein LiaF -
  O6R09_RS02115 (O6R09_02115) - 388682..389704 (+) 1023 WP_269725722.1 sensor histidine kinase -
  O6R09_RS02120 (O6R09_02120) - 389688..390332 (+) 645 WP_154454637.1 response regulator transcription factor -
  O6R09_RS02125 (O6R09_02125) - 390413..391816 (+) 1404 WP_269725723.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  O6R09_RS02130 (O6R09_02130) - 391813..392172 (+) 360 WP_154454635.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 646 a.a.        Molecular weight: 70001.78 Da        Isoelectric Point: 5.5722

>NTDB_id=767319 O6R09_RS02105 WP_235280521.1 385910..387850(+) (pknB) [Streptococcus alactolyticus strain LGM]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDNAPLANNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENKNVP
QALENVVIKATAKRLSDRYASTYEMSRDLMTALSYNRSREPKLVFEDTESAKPLPKVTTTTSVPSTTDQLLQKQKSAKEK
EGKDIEEVPPQNKKKSHQKKSRRMSGTLMKILIAIVAIVVAVFTYLTLTTPSTVRVPDVAETSLSEAKKTIEESGLEVGA
IHKVNNDTVKKNHVIKTSPTIGSAKKEGSAIDIYVSKGSAGFKIKDYSGKDYEEAIKDLVDNHGVSESQITVEKVTTSDY
PEGTIISQSPSEGSTFNPKGDKKITFKVAEEDTVVMPNLVGYTYSEAVAALNALGIPSSHITVYQATSGTSNYSQVPAPS
ASATVVSQTPYYGNQLDDSVTLYFSADEEVTPTTPSAPTTETSKSKASSSVPSSSSSSSSSGTETPATSSSDTTVDNSSV
PESSEN

Nucleotide


Download         Length: 1941 bp        

>NTDB_id=767319 O6R09_RS02105 WP_235280521.1 385910..387850(+) (pknB) [Streptococcus alactolyticus strain LGM]
ATGATTCAGATTGGCAAGTTGTTTGCTGGTCGTTATCGGATCCTTAAATCTATCGGACGGGGAGGAATGGCGGATGTTTA
TCTAGCAAAAGATTTAATTCTAGATAATGAAGAAGTGGCTATCAAGGTGCTTCGGACCAATTATCAGACAGATCAGATTG
CCGTAGCACGTTTCCAACGAGAAGCCCGTGCCATGGCAGAGCTTAATCATCCCAATATCGTTTCCATCCGAGATATTGGT
GAAGAAGACGGACAGCAATTCCTAGTAATGGAATATGTTGATGGGTCAGATTTGAAAAAATACATCCAAGATAACGCACC
GCTTGCTAATAATGAAGTGGTCAGAATCATGGAAGAAGTCTTGTCAGCCATGACCCTAGCCCATCAACAAGGTATTGTTC
ACCGTGATTTGAAACCCCAAAATATCTTATTAACCAAAGACGGAACGGTTAAAGTAACGGACTTTGGTATTGCCGTAGCC
TTTGCGGAAACAAGCTTGACCCAAACCAATTCCATGTTGGGAAGTGTGCATTATTTGTCACCAGAGCAAGCGCGTGGCTC
AAAAGCGACGGTCCAAAGTGATATTTATGCGATGGGGATTATGTTGTTTGAAATGTTGACAGGTCACATTCCTTATGATG
GGGATTCAGCCGTGACCATTGCTTTGCAACATTTCCAAAAGCCTCTTCCATCGATTATTGCTGAGAATAAAAATGTCCCT
CAAGCCTTGGAAAATGTGGTTATTAAGGCAACTGCCAAGCGTCTCAGTGACCGTTATGCGTCAACGTATGAAATGAGCCG
TGATTTGATGACTGCCCTTTCTTATAACCGCAGTCGCGAGCCTAAGCTTGTTTTTGAGGACACTGAAAGTGCCAAACCGT
TACCAAAAGTAACCACAACTACTTCAGTGCCATCAACAACCGATCAGCTATTGCAAAAGCAAAAATCTGCCAAGGAAAAA
GAAGGCAAGGACATTGAGGAAGTACCACCACAAAACAAGAAAAAGAGCCATCAAAAAAAATCGCGTCGAATGTCAGGAAC
GTTGATGAAGATTTTGATTGCTATTGTGGCTATCGTGGTTGCGGTCTTTACTTATTTGACCTTGACAACGCCATCGACTG
TCAGAGTGCCTGATGTCGCTGAAACAAGCTTATCAGAAGCCAAGAAAACCATCGAAGAATCAGGACTTGAGGTTGGTGCC
ATCCACAAAGTTAATAATGATACGGTTAAGAAAAACCATGTCATCAAGACTAGCCCGACAATTGGTTCTGCCAAAAAAGA
AGGCTCTGCTATTGACATCTATGTGTCAAAAGGCAGTGCTGGATTTAAGATCAAGGACTACTCAGGTAAGGATTACGAAG
AGGCGATAAAAGACTTGGTTGACAATCACGGTGTGTCAGAATCTCAAATCACAGTTGAAAAAGTGACGACTTCTGATTAT
CCTGAAGGTACTATTATCAGTCAAAGTCCGAGCGAAGGCTCAACCTTTAATCCAAAAGGCGATAAGAAAATTACCTTTAA
AGTAGCTGAGGAAGATACCGTTGTGATGCCAAATCTAGTTGGTTACACTTATTCAGAAGCTGTGGCGGCTTTGAATGCTT
TGGGTATTCCTAGTTCGCATATAACCGTTTACCAAGCAACGTCAGGAACAAGCAATTATAGCCAAGTACCTGCACCGTCG
GCTTCTGCAACGGTTGTTTCTCAAACGCCTTACTATGGTAACCAACTTGATGACAGTGTTACCCTTTACTTCTCAGCAGA
TGAAGAAGTGACACCAACCACACCGTCTGCGCCAACGACAGAAACGTCTAAATCAAAAGCGTCAAGTTCGGTTCCGTCAT
CATCTTCATCAAGTAGCAGTAGTGGCACAGAAACACCAGCAACGTCATCAAGCGACACTACTGTGGATAATAGTTCGGTG
CCAGAAAGTAGCGAAAACTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-253)

PASTA domain (PASTA)

(443-509)

PASTA domain (PASTA)

(514-585)

PASTA domain (PASTA)

(374-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

66.156

91.022

0.602
  stkP/pknB Streptococcus salivarius strain HSISS4

63.238

91.796

0.58
  stkP Streptococcus pneumoniae TIGR4

56.204

84.83

0.477
  stkP Streptococcus pneumoniae D39

56.022

84.83

0.475
  stkP Streptococcus pneumoniae R6

56.022

84.83

0.475
  stkP Streptococcus pneumoniae Rx1

55.839

84.83

0.474