Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   O6R09_RS01525 Genome accession   NZ_CP114883
Coordinates   262651..263406 (+) Length   251 a.a.
NCBI ID   WP_235280780.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 257651..268406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS01505 (O6R09_01505) - 258053..258793 (-) 741 WP_154454829.1 amino acid ABC transporter ATP-binding protein -
  O6R09_RS01510 (O6R09_01510) - 258793..260364 (-) 1572 WP_154454830.1 ABC transporter permease subunit -
  O6R09_RS01515 (O6R09_01515) - 260572..261525 (+) 954 WP_172018336.1 IS30 family transposase -
  O6R09_RS01520 (O6R09_01520) - 261671..262510 (+) 840 WP_154455424.1 undecaprenyl-diphosphate phosphatase -
  O6R09_RS01525 (O6R09_01525) mecA 262651..263406 (+) 756 WP_235280780.1 adaptor protein MecA Regulator
  O6R09_RS01530 (O6R09_01530) - 263408..264565 (+) 1158 WP_235280781.1 glycosyltransferase family 4 protein -
  O6R09_RS01535 (O6R09_01535) sufC 264689..265459 (+) 771 WP_154455421.1 Fe-S cluster assembly ATPase SufC -
  O6R09_RS01540 (O6R09_01540) sufD 265537..266799 (+) 1263 WP_154455420.1 Fe-S cluster assembly protein SufD -
  O6R09_RS01545 (O6R09_01545) - 266801..268033 (+) 1233 WP_269725699.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28999.74 Da        Isoelectric Point: 4.0555

>NTDB_id=767314 O6R09_RS01525 WP_235280780.1 262651..263406(+) (mecA) [Streptococcus alactolyticus strain LGM]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDTFKDSGMLSFRVTPRKDRIDVFVTKSEL
NKDLNFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTDAHEKLEKVEAMLENEADAAMASQEEAEASDEDINPSDYVHYV
LDFPDLKSVVAFAKVIDFPVEESELYKDQYSYHMTILLDLQNQPSYYANLMYARLLEYANPGTKTRAYLQEHGIEMLSTA
ALTKLKMIELM

Nucleotide


Download         Length: 756 bp        

>NTDB_id=767314 O6R09_RS01525 WP_235280780.1 262651..263406(+) (mecA) [Streptococcus alactolyticus strain LGM]
ATGGAAATGAAACAGATTAGTGAAACAACACTTAAAATAACGATTAGTATGGAAGATTTGGAAGAACGTGGTATGGAATT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTATTCTGTCATGGATGAATTGGATTTGCCAGATACCT
TTAAAGATAGCGGTATGCTTAGCTTCCGCGTGACTCCAAGAAAAGACCGTATCGATGTCTTTGTGACCAAATCAGAACTC
AATAAAGATTTGAATTTTGAAGATTTAGCGGCTTTTGATGACGTGTCAAATATGTCCCCAGAAGAATTTTTCAAGACACT
TGAACAAACCATGTTGTCAAAAGGGGATACAGATGCCCATGAAAAACTTGAAAAAGTCGAAGCGATGCTTGAAAATGAAG
CAGACGCTGCTATGGCAAGTCAAGAAGAAGCAGAAGCATCTGATGAGGATATCAATCCGTCAGATTATGTGCACTATGTG
CTTGATTTTCCAGACTTGAAGTCTGTCGTTGCCTTTGCCAAAGTCATTGATTTTCCAGTTGAAGAGTCTGAACTCTACAA
GGACCAATACAGTTACCACATGACGATTTTGCTTGATTTGCAAAATCAACCGTCTTATTATGCCAATTTGATGTATGCGC
GTTTATTGGAATACGCTAACCCAGGGACAAAAACACGTGCATATTTACAAGAACATGGTATTGAGATGCTCTCAACTGCC
GCCCTAACAAAATTAAAAATGATTGAGTTGATGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

65.323

98.805

0.645
  mecA Streptococcus thermophilus LMD-9

61.134

98.406

0.602
  mecA Streptococcus thermophilus LMG 18311

60.324

98.406

0.594
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.486