Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   O4M85_RS26515 Genome accession   NZ_CP114761
Coordinates   5643314..5644651 (+) Length   445 a.a.
NCBI ID   WP_003094694.1    Uniprot ID   A0A0H2ZG94
Organism   Pseudomonas aeruginosa strain NF143349     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5638314..5649651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O4M85_RS26490 (O4M85_26490) pgeF 5638457..5639185 (-) 729 WP_033972914.1 peptidoglycan editing factor PgeF -
  O4M85_RS26495 (O4M85_26495) rluD 5639182..5640144 (-) 963 WP_033972915.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  O4M85_RS26500 (O4M85_26500) - 5640290..5641315 (+) 1026 WP_033972916.1 outer membrane protein assembly factor BamD -
  O4M85_RS26505 (O4M85_26505) - 5641472..5641717 (+) 246 WP_003102591.1 PP0621 family protein -
  O4M85_RS26510 (O4M85_26510) pilS 5641707..5643299 (+) 1593 WP_039028118.1 two-component system sensor histidine kinase PilS Regulator
  O4M85_RS26515 (O4M85_26515) pilR 5643314..5644651 (+) 1338 WP_003094694.1 two-component system response regulator PilR Regulator
  O4M85_RS26520 (O4M85_26520) thiO 5644697..5645791 (-) 1095 WP_088376838.1 glycine oxidase ThiO -
  O4M85_RS26525 (O4M85_26525) - 5645926..5646435 (+) 510 WP_033976381.1 GspH/FimT family pseudopilin -
  O4M85_RS26530 (O4M85_26530) - 5646541..5647047 (+) 507 WP_003134935.1 GspH/FimT family pseudopilin -
  O4M85_RS26535 (O4M85_26535) pilV 5647038..5647595 (+) 558 WP_003125211.1 type 4a pilus minor pilin PilV Machinery gene
  O4M85_RS26540 (O4M85_26540) pilW 5647592..5648416 (+) 825 WP_033976380.1 type 4a pilus minor pilin PilW -
  O4M85_RS26545 (O4M85_26545) pilX 5648413..5649000 (+) 588 WP_033972921.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49737.06 Da        Isoelectric Point: 5.8654

>NTDB_id=766960 O4M85_RS26515 WP_003094694.1 5643314..5644651(+) (pilR) [Pseudomonas aeruginosa strain NF143349]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=766960 O4M85_RS26515 WP_003094694.1 5643314..5644651(+) (pilR) [Pseudomonas aeruginosa strain NF143349]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAGGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGGAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCCTGCGCAACCCGGAGGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAATCACCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCATGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGTGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGAGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCAGCCGAAGTCGGCGCCGGGCGCTTCCGCCAAGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAGCGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGACTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
TTTTCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGGAAGCTGATCATGCAGGCACTCGAGGAGACGCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZG94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

100

100

1
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384