Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QNK08_RS21275 Genome accession   NZ_CP125983
Coordinates   3992522..3993724 (-) Length   400 a.a.
NCBI ID   WP_046161071.1    Uniprot ID   -
Organism   Bacillus subtilis strain ZKY04     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3987522..3998724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNK08_RS21240 (QNK08_21255) - 3988000..3988953 (-) 954 WP_014481469.1 sporulation-delaying protein SdpB family protein -
  QNK08_RS21245 (QNK08_21260) - 3988938..3989492 (-) 555 WP_015715050.1 SdpA family antimicrobial peptide system protein -
  QNK08_RS21250 (QNK08_21265) - 3989676..3990311 (-) 636 WP_014481470.1 SdpI family protein -
  QNK08_RS21255 (QNK08_21270) - 3990311..3990595 (-) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  QNK08_RS21260 (QNK08_21275) rocR 3990822..3992207 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  QNK08_RS21265 (QNK08_21280) - 3992189..3992341 (-) 153 Protein_4134 ATP-binding protein -
  QNK08_RS21270 (QNK08_21285) - 3992369..3992501 (-) 133 Protein_4135 hypothetical protein -
  QNK08_RS21275 (QNK08_21290) htrA 3992522..3993724 (-) 1203 WP_046161071.1 serine protease HtrC Regulator
  QNK08_RS21280 (QNK08_21295) vicX 3993806..3994600 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  QNK08_RS21285 (QNK08_21300) walI 3994622..3995464 (-) 843 WP_014481473.1 WalRK two-component regulatory system regulator WalI -
  QNK08_RS21290 (QNK08_21305) walH 3995451..3996818 (-) 1368 WP_014481474.1 WalRK two-component regulatory system regulator WalH -
  QNK08_RS21295 (QNK08_21310) walK 3996808..3998643 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42733.46 Da        Isoelectric Point: 5.1904

>NTDB_id=766062 QNK08_RS21275 WP_046161071.1 3992522..3993724(-) (htrA) [Bacillus subtilis strain ZKY04]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=766062 QNK08_RS21275 WP_046161071.1 3992522..3993724(-) (htrA) [Bacillus subtilis strain ZKY04]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAATGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGGATTGAGATGAAATCGCTAAGCGACATTGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTTACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATTACGGAATTTGATGGATACAAGGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(199-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373