Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   OIY87_RS02635 Genome accession   NZ_CP113954
Coordinates   479338..481215 (+) Length   625 a.a.
NCBI ID   WP_234756266.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain XH2168     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 474338..486215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIY87_RS02620 (OIY87_03915) fmt 476316..477251 (+) 936 WP_234756270.1 methionyl-tRNA formyltransferase -
  OIY87_RS02625 (OIY87_03920) rsmB 477241..478563 (+) 1323 WP_234756268.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  OIY87_RS02630 (OIY87_03925) - 478601..479338 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  OIY87_RS02635 (OIY87_03930) pknB 479338..481215 (+) 1878 WP_234756266.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  OIY87_RS02640 (OIY87_03935) liaF 481326..482021 (+) 696 WP_009853569.1 cell wall-active antibiotics response protein LiaF -
  OIY87_RS02645 (OIY87_03940) - 482018..483043 (+) 1026 WP_012961538.1 sensor histidine kinase -
  OIY87_RS02650 (OIY87_03945) - 483027..483671 (+) 645 WP_009853571.1 response regulator transcription factor -
  OIY87_RS02655 (OIY87_03950) - 483790..485190 (+) 1401 WP_009853572.1 Cof-type HAD-IIB family hydrolase -
  OIY87_RS02660 (OIY87_03955) - 485190..485546 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67714.93 Da        Isoelectric Point: 5.0759

>NTDB_id=763814 OIY87_RS02635 WP_234756266.1 479338..481215(+) (pknB) [Streptococcus gallolyticus strain XH2168]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KVATENKATKAKTKKKKSRRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSSLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVAAESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATVTAQTPYYGETLSGNVVLYLAADEEESSQAPSSSSSESSESKESSSSSSSTDDSSSSTETSDE

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=763814 OIY87_RS02635 WP_234756266.1 479338..481215(+) (pknB) [Streptococcus gallolyticus strain XH2168]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTTGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGAATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGACGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCTGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAAAATGTGCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGTAGCAACAGAAAACAAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAAGTCTTAAAGTTGGAACTGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTTAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTATGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATTAGTCAAACGCCTAGCGAAGGTGAAACCTTTAAGGTAAGTGGCGATGATAAGATTACCTTTAAAGTAGCCGC
AGAAAGCACAGTAACAATGCCAAATCTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTGACGGCTCTAGGTGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTGTCACTGCTCAGACACCTTATTATGGTGAAACGTTAAGTGGTAACGTGGTACTTTATCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCACCATCGTCATCAAGCTCAGAATCCTCTGAATCAAAAGAATCAAGTTCATCAAGCAGTAGTACAG
ATGACAGTAGCTCATCGACAGAAACAAGTGATGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-575)

PASTA domain (PASTA)

(371-434)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.313

93.92

0.642
  stkP/pknB Streptococcus salivarius strain HSISS4

64.856

94.24

0.611
  stkP Streptococcus pneumoniae TIGR4

54.452

93.44

0.509
  stkP Streptococcus pneumoniae D39

54.281

93.44

0.507
  stkP Streptococcus pneumoniae R6

54.281

93.44

0.507
  stkP Streptococcus pneumoniae Rx1

54.11

93.44

0.506