Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   OYT93_RS05925 Genome accession   NZ_CP113947
Coordinates   1182080..1184233 (+) Length   717 a.a.
NCBI ID   WP_268767247.1    Uniprot ID   -
Organism   Leuconostoc pseudomesenteroides strain L64     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1144635..1184233 1182080..1184233 within 0


Gene organization within MGE regions


Location: 1144635..1184233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OYT93_RS05690 (OYT93_05690) - 1144635..1144892 (+) 258 WP_031941341.1 hypothetical protein -
  OYT93_RS05695 (OYT93_05695) - 1145013..1145333 (-) 321 WP_139968702.1 MazG nucleotide pyrophosphohydrolase domain-containing protein -
  OYT93_RS05700 (OYT93_05700) - 1145350..1145604 (-) 255 Protein_1094 hypothetical protein -
  OYT93_RS05705 (OYT93_05705) - 1145693..1145935 (+) 243 WP_139968603.1 transposase -
  OYT93_RS05710 (OYT93_05710) - 1145981..1146784 (+) 804 WP_187241104.1 IS3 family transposase -
  OYT93_RS05715 (OYT93_05715) - 1147012..1147230 (-) 219 WP_233610758.1 hypothetical protein -
  OYT93_RS05720 (OYT93_05720) - 1147199..1147474 (-) 276 WP_147651565.1 hypothetical protein -
  OYT93_RS05725 (OYT93_05725) - 1147502..1148089 (-) 588 WP_268767225.1 hypothetical protein -
  OYT93_RS05730 (OYT93_05730) - 1148141..1148473 (-) 333 WP_233610761.1 replication initiator protein A -
  OYT93_RS05735 (OYT93_05735) - 1148463..1148696 (-) 234 WP_147651567.1 helix-turn-helix transcriptional regulator -
  OYT93_RS05740 (OYT93_05740) - 1148969..1149900 (-) 932 Protein_1102 IS30 family transposase -
  OYT93_RS05745 (OYT93_05745) - 1150107..1150622 (-) 516 WP_139968719.1 Asp23/Gls24 family envelope stress response protein -
  OYT93_RS05750 (OYT93_05750) - 1150681..1150875 (-) 195 WP_139968718.1 DUF2273 domain-containing protein -
  OYT93_RS05755 (OYT93_05755) amaP 1150894..1151457 (-) 564 WP_268767226.1 alkaline shock response membrane anchor protein AmaP -
  OYT93_RS05760 (OYT93_05760) - 1151587..1151996 (-) 410 Protein_1106 hypothetical protein -
  OYT93_RS05765 (OYT93_05765) - 1152214..1152396 (+) 183 Protein_1107 D-2-hydroxyacid dehydrogenase -
  OYT93_RS05770 (OYT93_05770) - 1152455..1152715 (+) 261 WP_050884923.1 transposase -
  OYT93_RS05775 (OYT93_05775) - 1152724..1153530 (+) 807 WP_268767222.1 IS3 family transposase -
  OYT93_RS05780 (OYT93_05780) - 1153558..1154367 (+) 810 WP_268767227.1 Rgg/GadR/MutR family transcriptional regulator -
  OYT93_RS05785 (OYT93_05785) - 1154551..1154841 (+) 291 WP_268767228.1 hypothetical protein -
  OYT93_RS05790 (OYT93_05790) - 1154853..1155902 (-) 1050 WP_268767229.1 2,3-butanediol dehydrogenase -
  OYT93_RS05795 (OYT93_05795) - 1156136..1156969 (+) 834 WP_260346004.1 aldo/keto reductase -
  OYT93_RS05800 (OYT93_05800) - 1157027..1158433 (-) 1407 WP_268767230.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  OYT93_RS05805 (OYT93_05805) - 1158594..1159595 (-) 1002 WP_260346006.1 alpha/beta hydrolase -
  OYT93_RS05810 (OYT93_05810) - 1159739..1160473 (-) 735 WP_260346007.1 3-oxoacyl-ACP reductase -
  OYT93_RS05815 (OYT93_05815) - 1160473..1161030 (-) 558 WP_268767231.1 QueT transporter family protein -
  OYT93_RS05820 (OYT93_05820) rpoD 1161133..1162431 (-) 1299 WP_010295445.1 RNA polymerase sigma factor RpoD -
  OYT93_RS05825 (OYT93_05825) dnaG 1162466..1164328 (-) 1863 WP_260346010.1 DNA primase -
  OYT93_RS05830 (OYT93_05830) - 1164836..1165831 (-) 996 WP_268767232.1 IS30 family transposase -
  OYT93_RS05835 (OYT93_05835) - 1166389..1168407 (-) 2019 WP_268767233.1 SspB-related isopeptide-forming adhesin -
  OYT93_RS05840 (OYT93_05840) - 1168473..1169354 (-) 882 WP_268767234.1 class A sortase -
  OYT93_RS05845 (OYT93_05845) - 1169365..1170228 (-) 864 WP_268767235.1 hypothetical protein -
  OYT93_RS05850 (OYT93_05850) - 1170274..1171518 (-) 1245 WP_268767236.1 hypothetical protein -
  OYT93_RS05855 (OYT93_05855) - 1171534..1171923 (-) 390 WP_268767237.1 hypothetical protein -
  OYT93_RS05860 (OYT93_05860) - 1172082..1172531 (-) 450 WP_268767238.1 Type 1 glutamine amidotransferase-like domain-containing protein -
  OYT93_RS05865 (OYT93_05865) - 1172528..1172704 (-) 177 WP_268767239.1 hypothetical protein -
  OYT93_RS05870 (OYT93_05870) - 1172847..1173365 (+) 519 WP_268767240.1 GNAT family N-acetyltransferase -
  OYT93_RS05875 (OYT93_05875) - 1173450..1173965 (+) 516 WP_268767241.1 nucleoside 2-deoxyribosyltransferase -
  OYT93_RS05880 (OYT93_05880) - 1174195..1174422 (-) 228 WP_268767242.1 hypothetical protein -
  OYT93_RS05885 (OYT93_05885) - 1174599..1175405 (-) 807 WP_268767243.1 IS3 family transposase -
  OYT93_RS05890 (OYT93_05890) - 1175451..1175693 (-) 243 WP_036088706.1 transposase -
  OYT93_RS05895 (OYT93_05895) - 1175761..1176678 (-) 918 Protein_1133 Y-family DNA polymerase -
  OYT93_RS05900 (OYT93_05900) - 1176900..1177004 (-) 105 WP_412757270.1 putative holin-like toxin -
  OYT93_RS05905 (OYT93_05905) - 1177221..1179878 (+) 2658 WP_268767244.1 DEAD/DEAH box helicase family protein -
  OYT93_RS10600 (OYT93_05910) - 1180052..1180129 (-) 78 WP_268767795.1 putative holin-like toxin -
  OYT93_RS10605 - 1180800..1181204 (+) 405 WP_412757856.1 CPBP family intramembrane glutamic endopeptidase -
  OYT93_RS05915 (OYT93_05915) - 1181311..1181472 (-) 162 WP_268767245.1 hypothetical protein -
  OYT93_RS05920 (OYT93_05920) - 1181636..1182031 (+) 396 WP_268767246.1 hypothetical protein -
  OYT93_RS05925 (OYT93_05925) comA 1182080..1184233 (+) 2154 WP_268767247.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 79300.24 Da        Isoelectric Point: 6.5150

>NTDB_id=763729 OYT93_RS05925 WP_268767247.1 1182080..1184233(+) (comA) [Leuconostoc pseudomesenteroides strain L64]
MSFKTINYIAQVDERDCGVAALAMVLVNYKTRLSLAKLRDLAKTDMEGTTALGIVKAANALDFETMPIQADLSLFDKKDL
PYPFIAHVIKEGKYPHYYVVYGMKGDQLLIADPDNTVGKTKMTKARFNEEWTGVSIFIAPNPTYKPTKEKKRSLSSFIPV
ITRQKLLVINIVIAALLVTLVSILGSYYLQGIIDTYIPDNMKNTLGIVSIGLIFAYVIQQLLSYARDYLLIVMGQRLSID
IILSYIKHIFELPMSFFATRRTGEIVSRFTDANAIIEALASTMLSVFLDLGILVIVGTVLVVQNSTLFLISLIAIPAYAL
VVWLFMRPFSKMNNDQMQAGSMLSSSIIEDINGVETIKALNSEATAYHKIDHEFVTYLEKSFVYAKTEAVQNAIKSLLQL
SLNVVILWVGAQLVMTNKISVGQLITYNALLGFFTDPLQNIINLQTKLQQASVANNRLNEVYLVDSEFKDSHQMTERITT
NSSLVADHITYKYGFGAPAIDDVSLTITAGEKIALVGISGSGKSTLVKLLVNFFQPESGTISLGQTPLANLDKHELRAHI
NYLPQEPFIFSGSIMDNLLLGSKPGTTQEDVIRAVEIAEIKDDIEKMSQGFGTELAESGNISGGQKQRIALARAILVDSP
VMILDESTSNLDVLTEKKIIDNLMQLTEKTIIFVAHRLTISQRVDRILTMKSGKIIEDGTHNALINAGGFYASLFNH

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=763729 OYT93_RS05925 WP_268767247.1 1182080..1184233(+) (comA) [Leuconostoc pseudomesenteroides strain L64]
ATGTCTTTCAAAACAATAAATTATATCGCACAAGTAGATGAACGTGATTGTGGTGTTGCTGCACTAGCTATGGTGTTAGT
TAATTACAAGACACGCCTATCCTTAGCAAAACTGCGTGACCTAGCCAAAACAGACATGGAAGGAACAACTGCTTTAGGCA
TTGTTAAAGCCGCTAATGCACTAGATTTTGAAACCATGCCGATTCAGGCTGATTTGAGTTTATTCGATAAAAAAGATTTA
CCCTATCCTTTTATTGCTCATGTGATTAAAGAAGGTAAATACCCGCATTATTATGTTGTCTATGGCATGAAAGGTGATCA
GTTACTAATTGCTGATCCAGATAATACCGTTGGAAAGACTAAAATGACGAAAGCGCGTTTTAACGAGGAATGGACCGGCG
TGTCCATTTTTATTGCGCCCAATCCGACCTACAAACCCACGAAAGAAAAAAAGCGTTCCTTGAGTTCGTTTATTCCAGTG
ATCACGCGACAAAAGCTATTAGTCATCAATATTGTCATTGCCGCCTTATTAGTAACCCTTGTGAGCATTTTAGGATCGTA
TTATTTACAGGGTATCATTGATACTTATATCCCCGATAACATGAAAAACACCTTAGGGATTGTGTCAATAGGGCTTATTT
TTGCTTATGTTATCCAACAATTGCTCTCTTATGCCAGAGATTATTTATTAATTGTCATGGGACAACGACTCTCAATTGAT
ATTATCTTGTCCTATATCAAACATATCTTTGAACTGCCAATGTCTTTTTTTGCAACGCGTCGTACCGGTGAAATTGTGAG
TCGTTTTACGGACGCTAATGCCATTATTGAAGCCCTGGCAAGCACGATGTTATCAGTCTTTTTAGACTTAGGTATTTTGG
TCATTGTCGGCACCGTGCTAGTCGTTCAAAATTCAACCTTATTTTTGATATCTCTGATTGCTATTCCGGCTTATGCCCTA
GTGGTCTGGCTCTTTATGCGTCCTTTTTCAAAGATGAATAATGACCAAATGCAAGCAGGTTCGATGTTAAGCTCTTCCAT
TATTGAAGATATTAATGGCGTTGAGACGATTAAAGCGCTGAATAGTGAAGCAACTGCCTATCATAAAATTGATCATGAAT
TTGTCACTTATTTAGAAAAATCATTTGTTTACGCTAAAACAGAAGCCGTTCAAAATGCGATTAAAAGTCTCTTACAGCTC
TCTTTAAATGTCGTGATCTTATGGGTTGGTGCACAACTGGTCATGACCAATAAAATTAGTGTTGGTCAACTGATCACTTA
CAATGCTTTATTAGGATTTTTTACGGATCCCTTGCAAAATATTATTAATTTACAAACTAAGCTCCAGCAGGCCTCAGTCG
CTAATAACCGTTTGAACGAAGTGTATTTGGTTGATTCAGAATTTAAAGATAGTCATCAAATGACAGAAAGGATTACGACT
AACAGCTCACTAGTAGCCGATCATATTACCTATAAATACGGTTTTGGCGCCCCAGCGATTGATGATGTTTCACTAACCAT
TACAGCCGGTGAAAAAATCGCTTTGGTTGGGATTAGTGGATCAGGAAAATCAACTTTAGTTAAATTGCTTGTTAATTTCT
TTCAACCAGAGTCAGGGACAATCTCACTGGGACAAACACCACTCGCTAATCTTGATAAACACGAGCTAAGAGCACACATT
AATTATTTACCACAAGAACCCTTTATCTTTTCCGGTTCCATTATGGATAACCTGCTATTAGGGTCTAAACCAGGGACAAC
CCAGGAAGATGTTATTCGAGCAGTAGAAATTGCTGAAATTAAAGATGATATTGAAAAAATGTCGCAAGGATTTGGTACTG
AGCTGGCCGAAAGTGGTAATATTTCGGGTGGTCAAAAACAACGCATTGCTTTAGCAAGGGCTATTTTAGTCGATTCTCCT
GTGATGATTTTAGATGAGTCAACCAGTAATCTTGACGTTTTAACAGAAAAAAAGATTATTGATAATCTCATGCAGTTAAC
CGAAAAGACCATTATCTTTGTAGCGCACCGCTTAACTATTTCACAGCGAGTGGATCGGATTTTGACCATGAAAAGTGGCA
AGATTATCGAAGATGGCACGCATAATGCTCTGATTAATGCCGGTGGTTTCTACGCATCACTATTTAATCATTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(501-649)

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter transmembrane region (ABC_membrane)

(168-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

60.251

100

0.603
  comA Streptococcus gordonii str. Challis substr. CH1

59.833

100

0.598
  comA Streptococcus mitis SK321

59.554

100

0.596
  comA Streptococcus pneumoniae Rx1

59.554

100

0.596
  comA Streptococcus pneumoniae D39

59.554

100

0.596
  comA Streptococcus pneumoniae R6

59.554

100

0.596
  comA Streptococcus pneumoniae TIGR4

59.414

100

0.594
  comA/nlmT Streptococcus mutans UA159

58.898

98.745

0.582