Detailed information NTG0763683

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: OZX59_RS08755
• Genome accession: NZ_CP113943
• Coordinates: 1813980..1816130 (+)
• Length: 716 a.a.
• NCBI ID: WP_277125993.1
• Uniprot ID: -
• Organism: Lactobacillus sp. ESL0681
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1808980..1821130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OZX59_RS08715 (OZX59_08715)	-	1809050..1809193 (-)	144	WP_277125980.1	bacteriocin	-
OZX59_RS08720 (OZX59_08720)	-	1809222..1809365 (-)	144	WP_277125981.1	hypothetical protein	-
OZX59_RS08725 (OZX59_08725)	-	1809937..1810971 (+)	1035	WP_277125983.1	IS30 family transposase	-
OZX59_RS08730 (OZX59_08730)	-	1811765..1812346 (-)	582	WP_277125984.1	thioredoxin fold domain-containing protein	-
OZX59_RS08735 (OZX59_08735)	-	1812420..1812767 (-)	348	WP_277125985.1	hypothetical protein	-
OZX59_RS08740 (OZX59_08740)	-	1812792..1813169 (-)	378	WP_277125987.1	hypothetical protein	-
OZX59_RS08745 (OZX59_08745)	-	1813322..1813519 (-)	198	WP_277125989.1	Blp family class II bacteriocin	-
OZX59_RS08750 (OZX59_08750)	-	1813545..1813793 (-)	249	WP_277125991.1	Blp family class II bacteriocin	-
OZX59_RS08755 (OZX59_08755)	comA	1813980..1816130 (+)	2151	WP_277125993.1	peptide cleavage/export ABC transporter	Regulator
OZX59_RS08760 (OZX59_08760)	-	1816146..1817240 (+)	1095	WP_277125995.1	HlyD family efflux transporter periplasmic adaptor subunit	-
OZX59_RS08765 (OZX59_08765)	pbp4b	1817471..1819408 (+)	1938	WP_277125997.1	penicillin binding protein PBP4B	-
OZX59_RS08770 (OZX59_08770)	-	1819438..1820334 (+)	897	WP_277125999.1	alpha/beta fold hydrolase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 79465.93 Da
• Isoelectric Point: 7.9521

>NTDB_id=763683 OZX59_RS08755 WP_277125993.1 1813980..1816130(+) (comA) [Lactobacillus sp. ESL0681]
MYNKIYIQQVDETDCGVAALAMLFKHFGIQVSLAKLRNLAKTDQMGTTALGLVKTAQKFGFETKAIKADMSLFDVKDLPL
PFIAHVIKNQELEHYYVVLKVGKKTVTIADPDGSVGVVKISKAKFEQEWTGVAIFIAPKATYEPVKEKKNSLFSFIPGLL
KQKKLLLNIVLAALLTTLISIVGSYFLQAIIDTYIPNNLQNTLAIIAIGLIVFYVFQAIFTYAQNFLLAILGQRLSIEII
LGYIKHIFKLPMEFFATRNTGEIVSRFSDASKIIDALASAVLSMLLDVGIVVIMGVILGIQSSKLFLITLISLPIYVVII
LAFTKPFERLNQKEMEANSVVSSSIIEDIRGIETIKGLNSEDTRYQKIDSEFVDFLKKSLAYTKSDTLQQAIKLFVQLAL
EVVILWTGAGLVIHNELSVGQLMTYNALLSFFVNPLQNIINLQPKLQSAQVANNRLNEVFLVESEFKQTRPVKQVSQLAG
PIELKNVSYQYGYGADVLHQINLTIPANEKLTIVGMSGSGKSTLVKLLVNFFEPKSGQILINGHDLQNIDKHTLRSYVNY
LPQDPYLFSGTILDNLKLGNRSDTSPDDILAACQTALIADDIAKMPMQFETHLDEDATVLSGGQKQRLAIARALLSPAKV
LILDESTSGLDTITEKRLVKNLLKLSDRTIIFIAHRLSIARETDNIVVLNNGKLVEQGMHADLLAQHGYYYDLVSE

Nucleotide

• Length: 2151 bp

>NTDB_id=763683 OZX59_RS08755 WP_277125993.1 1813980..1816130(+) (comA) [Lactobacillus sp. ESL0681]
ATGTATAATAAAATTTATATACAACAGGTTGATGAGACCGATTGTGGGGTAGCGGCTCTGGCGATGTTGTTCAAGCACTT
TGGAATTCAAGTTTCTTTAGCCAAGTTGCGTAACTTGGCCAAGACTGATCAAATGGGAACGACAGCACTTGGCTTGGTCA
AGACTGCTCAGAAGTTTGGTTTTGAAACTAAAGCAATTAAGGCAGATATGTCATTATTTGATGTCAAAGACTTACCACTA
CCATTTATTGCACATGTGATTAAAAATCAAGAACTTGAACATTACTATGTTGTGCTAAAAGTGGGTAAAAAAACGGTGAC
GATAGCTGACCCAGATGGGTCAGTTGGCGTTGTGAAAATATCCAAGGCTAAGTTCGAACAAGAGTGGACTGGGGTGGCAA
TCTTTATTGCACCTAAGGCTACCTATGAACCGGTGAAAGAAAAGAAAAATTCTTTATTCTCTTTTATTCCAGGCTTACTT
AAGCAAAAGAAGCTGCTACTTAACATTGTGCTAGCAGCTTTATTGACCACACTTATCAGTATTGTTGGCTCGTATTTCTT
ACAAGCGATCATTGATACTTACATTCCGAATAACTTACAGAATACTTTGGCAATTATTGCAATCGGATTAATCGTGTTCT
ATGTTTTTCAAGCGATTTTCACCTATGCGCAGAATTTCCTCTTAGCAATTCTGGGGCAACGGCTATCGATTGAAATTATT
CTGGGTTACATTAAGCACATTTTTAAGTTGCCTATGGAATTCTTCGCCACTCGCAATACTGGTGAGATTGTCTCCCGTTT
CTCAGATGCTAGTAAGATTATTGATGCACTTGCTAGTGCTGTCTTATCCATGTTACTAGATGTTGGTATTGTGGTCATTA
TGGGGGTCATTCTAGGAATTCAAAGTAGCAAACTATTTTTAATTACGTTAATTTCTCTTCCTATTTATGTCGTAATTATC
CTTGCCTTTACTAAACCGTTTGAACGCCTTAATCAAAAGGAAATGGAAGCTAATAGTGTAGTTAGTTCTTCAATTATTGA
AGATATTCGTGGAATTGAAACGATTAAGGGCCTAAATAGTGAAGATACCCGTTATCAAAAGATTGATAGTGAGTTTGTTG
ACTTCCTTAAGAAGAGTTTGGCTTATACTAAGTCAGATACGTTGCAACAGGCAATTAAGTTGTTCGTCCAGTTAGCCTTA
GAAGTTGTTATCTTATGGACTGGGGCTGGCTTAGTCATTCATAACGAATTGTCGGTTGGTCAATTGATGACTTACAATGC
TTTATTATCCTTTTTCGTTAATCCTTTACAGAATATTATTAACTTACAACCTAAGTTGCAGAGCGCCCAAGTAGCTAATA
ATCGGTTAAATGAGGTCTTTTTGGTCGAGAGTGAATTTAAACAGACTAGACCAGTCAAGCAGGTTAGTCAGTTGGCAGGA
CCAATTGAATTAAAGAATGTCTCCTACCAATATGGCTATGGCGCAGATGTCCTACACCAGATTAATTTAACGATTCCAGC
TAATGAAAAGTTAACCATTGTTGGTATGAGTGGATCGGGTAAGTCCACGTTGGTTAAGTTGCTAGTTAATTTCTTTGAGC
CAAAGTCAGGCCAAATTTTGATTAATGGTCATGATTTACAGAATATTGATAAGCATACTTTGCGCAGCTATGTTAATTAT
CTGCCTCAAGATCCGTATTTATTTTCAGGGACAATTCTTGATAACTTAAAGTTAGGTAACCGGTCAGATACTAGTCCAGA
TGATATTTTGGCGGCTTGTCAGACAGCATTAATTGCAGATGATATTGCGAAAATGCCAATGCAATTTGAAACTCATCTTG
ACGAAGACGCAACAGTTCTGTCAGGTGGACAGAAGCAGCGTTTGGCAATTGCTCGTGCATTATTATCACCAGCTAAAGTG
TTGATCTTAGATGAGTCAACCAGTGGACTAGATACTATTACCGAAAAACGACTAGTTAAGAATCTCTTGAAGTTGTCTGA
TCGCACCATTATTTTTATTGCGCATCGTTTATCGATTGCCCGAGAAACAGACAATATCGTGGTACTTAATAATGGTAAGT
TAGTGGAACAAGGTATGCATGCAGACTTGTTAGCACAGCATGGCTATTACTATGATTTGGTCAGTGAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-648)

• Peptidase C39 family (Peptidase_C39) (6-140)

• ABC transporter transmembrane region (ABC_membrane) (167-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	59.577	99.162	0.591
comA	Streptococcus mitis SK321	59.014	99.162	0.585
comA	Streptococcus pneumoniae Rx1	59.014	99.162	0.585
comA	Streptococcus pneumoniae D39	59.014	99.162	0.585
comA	Streptococcus pneumoniae R6	59.014	99.162	0.585
comA	Streptococcus pneumoniae TIGR4	58.873	99.162	0.584
comA	Streptococcus gordonii str. Challis substr. CH1	57.746	99.162	0.573
comA/nlmT	Streptococcus mutans UA159	55.587	98.743	0.549