Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   OZX56_RS06730 Genome accession   NZ_CP113941
Coordinates   1388187..1390337 (-) Length   716 a.a.
NCBI ID   WP_277139365.1    Uniprot ID   -
Organism   Lactobacillus sp. ESL0684     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1383187..1395337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OZX56_RS06715 (OZX56_06715) - 1383986..1384882 (-) 897 WP_277139362.1 alpha/beta fold hydrolase -
  OZX56_RS06720 (OZX56_06720) pbp4b 1384911..1386845 (-) 1935 WP_277139363.1 penicillin binding protein PBP4B -
  OZX56_RS06725 (OZX56_06725) - 1387077..1388171 (-) 1095 WP_277139364.1 HlyD family efflux transporter periplasmic adaptor subunit -
  OZX56_RS06730 (OZX56_06730) comA 1388187..1390337 (-) 2151 WP_277139365.1 peptide cleavage/export ABC transporter Regulator
  OZX56_RS06735 (OZX56_06735) - 1390509..1390700 (+) 192 WP_277139366.1 hypothetical protein -
  OZX56_RS06740 (OZX56_06740) - 1390732..1390899 (+) 168 WP_277139367.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  OZX56_RS06745 (OZX56_06745) - 1390997..1392193 (+) 1197 WP_277139368.1 CPBP family intramembrane glutamic endopeptidase -
  OZX56_RS06750 (OZX56_06750) - 1392220..1392369 (+) 150 WP_277139369.1 bacteriocin -
  OZX56_RS06755 (OZX56_06755) - 1392587..1392730 (+) 144 WP_277139370.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79453.87 Da        Isoelectric Point: 7.9521

>NTDB_id=763659 OZX56_RS06730 WP_277139365.1 1388187..1390337(-) (comA) [Lactobacillus sp. ESL0684]
MYNKIYIQQVDETDCGVAALAMLFKHFGTQVSLAKLRNLAKTDQMGTTALGLVKTAQKFGFETKAIKADMSLFDVKDLPL
PFIAHVIKNQELEHYYVVLKVGKKTVTIADPDGSVGVVKISKAKFEQEWTGVAIFIAPKATYEPVKEKKNSLFSFIPGLL
KQKKLLLNIVLAALLTTLISIVGSYFLQAIIDTYIPNNLQNTLAIIAIGLIVFYVFQAIFTYAQNFLLAILGQRLSIEII
LGYIKHIFKLPMEFFATRNTGEIVSRFSDASKIIDALASAVLSMLLDVGIVVIMGVILGIQSSKLFLITLISLPIYVVII
LAFTKPFERLNQKEMEANSVVSSSIIEDIRGIETIKGLNSEDTRYQKIDSEFVDFLKKSLAYTKSDTLQQAIKLFVQLAL
EVVILWTGAGLVIHNELSVGQLMTYNALLSFFVNPLQNIINLQPKLQSAQVANNRLNEVFLVESEFKQTRPVKQVSQLAG
PIELKNVSYQYGYGADVLHQINLTIPANEKLTIVGMSGSGKSTLVKLLVNFFEPKSGQILINGHDLQNIDKHTLRSYVNY
LPQDPYLFSGTILDNLKLGNRSDTSPDDILAACQTALIADDIAKMPMQFETHLDEDATVLSGGQKQRLAIARALLSPAKV
LILDESTSGLDTITEKRLVKNLLKLSDRTIIFIAHRLSIARETDNIVVLNNGKLVEQGMHADLLAQHGYYYDLVSE

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=763659 OZX56_RS06730 WP_277139365.1 1388187..1390337(-) (comA) [Lactobacillus sp. ESL0684]
ATGTATAATAAAATTTATATACAACAGGTTGATGAGACCGATTGTGGGGTAGCGGCTCTGGCGATGTTGTTCAAGCACTT
TGGAACTCAAGTTTCTTTAGCCAAGTTGCGTAACTTGGCCAAGACTGATCAAATGGGAACGACAGCACTTGGCTTGGTCA
AGACTGCTCAGAAGTTTGGTTTTGAAACTAAAGCAATTAAGGCAGATATGTCATTATTTGATGTCAAAGACTTACCACTA
CCATTTATTGCACATGTGATTAAAAATCAAGAACTTGAACATTACTATGTTGTGCTAAAAGTGGGTAAAAAAACGGTGAC
GATAGCTGACCCAGATGGGTCAGTTGGCGTTGTGAAAATATCCAAGGCTAAGTTCGAACAAGAGTGGACTGGGGTGGCAA
TCTTTATTGCACCTAAGGCTACCTATGAACCGGTGAAAGAAAAGAAAAATTCTTTATTCTCTTTTATTCCAGGCTTACTT
AAGCAAAAGAAGCTGCTACTTAACATTGTGCTAGCAGCTTTATTGACCACACTTATCAGTATTGTTGGCTCGTATTTCTT
ACAAGCGATCATTGATACTTACATTCCGAATAACTTACAGAATACTTTGGCAATTATTGCAATCGGATTAATCGTGTTCT
ATGTTTTTCAAGCGATTTTCACCTATGCGCAGAATTTCCTCTTAGCAATTCTGGGGCAACGGCTATCGATTGAAATTATT
CTGGGTTACATTAAGCACATTTTTAAGTTGCCTATGGAATTCTTCGCCACTCGCAATACTGGTGAGATTGTCTCCCGTTT
CTCAGATGCTAGTAAGATTATTGATGCACTTGCTAGTGCTGTCTTATCCATGTTACTAGATGTTGGTATTGTGGTCATTA
TGGGGGTCATTCTAGGAATTCAAAGTAGCAAACTATTTTTAATTACGTTAATTTCTCTTCCTATTTATGTCGTAATTATC
CTTGCCTTTACTAAACCGTTTGAACGCCTTAATCAAAAGGAAATGGAAGCTAATAGTGTAGTTAGTTCTTCAATTATTGA
AGATATTCGTGGAATTGAAACGATTAAGGGCCTAAATAGTGAAGATACTCGTTACCAAAAGATAGATAGTGAGTTTGTTG
ACTTCCTTAAGAAGAGTTTGGCTTATACTAAGTCAGATACGTTGCAACAGGCAATTAAGTTGTTCGTCCAGTTAGCCTTA
GAAGTTGTTATCTTATGGACTGGGGCTGGCTTAGTCATTCATAACGAATTGTCGGTTGGTCAATTGATGACTTACAATGC
TTTATTATCCTTTTTCGTTAATCCTTTACAGAATATTATTAACTTACAACCTAAGTTGCAGAGCGCCCAAGTAGCTAATA
ATCGGTTAAATGAGGTCTTTTTGGTCGAGAGTGAATTTAAACAGACTAGACCAGTCAAGCAGGTTAGTCAGTTGGCAGGA
CCAATTGAATTAAAGAATGTCTCCTACCAATATGGCTATGGCGCAGATGTCCTACACCAGATTAATTTAACGATTCCAGC
TAATGAAAAGTTAACCATTGTTGGTATGAGTGGATCGGGTAAGTCCACGTTGGTTAAGTTGCTAGTTAATTTCTTTGAGC
CAAAGTCAGGCCAAATTTTGATTAATGGTCATGATTTACAGAATATTGATAAGCATACTTTGCGCAGCTATGTTAATTAT
CTGCCTCAAGATCCGTATTTATTTTCAGGGACAATTCTTGATAACTTAAAGTTAGGTAACCGGTCAGATACTAGTCCAGA
TGATATTTTGGCGGCTTGTCAGACAGCATTAATTGCAGATGATATTGCGAAAATGCCAATGCAATTTGAAACTCATCTTG
ACGAAGACGCAACAGTTCTGTCAGGTGGACAGAAGCAGCGTTTGGCAATTGCTCGTGCATTATTATCACCAGCTAAAGTG
TTGATCTTAGATGAGTCAACCAGTGGACTAGATACTATTACCGAAAAACGACTAGTTAAGAATCTCTTGAAGTTGTCTGA
TCGCACCATTATTTTTATTGCGCATCGTTTATCGATTGCCCGAGAAACAGACAATATCGTGGTACTTAATAATGGTAAGT
TAGTGGAACAAGGTATGCATGCAGACTTGTTAGCACAGCATGGCTATTACTATGATTTGGTCAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(498-648)

Peptidase C39 family (Peptidase_C39)

(6-140)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

59.577

99.162

0.591
  comA Streptococcus mitis SK321

59.014

99.162

0.585
  comA Streptococcus pneumoniae Rx1

59.014

99.162

0.585
  comA Streptococcus pneumoniae D39

59.014

99.162

0.585
  comA Streptococcus pneumoniae R6

59.014

99.162

0.585
  comA Streptococcus pneumoniae TIGR4

58.873

99.162

0.584
  comA Streptococcus gordonii str. Challis substr. CH1

57.746

99.162

0.573
  comA/nlmT Streptococcus mutans UA159

55.587

98.743

0.549