Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   OZF29_RS12165 Genome accession   NZ_CP113832
Coordinates   2508436..2509734 (+) Length   432 a.a.
NCBI ID   WP_116495166.1    Uniprot ID   -
Organism   Enterococcus faecalis strain M61     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2503436..2514734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OZF29_RS12140 (OZF29_12140) - 2503719..2504183 (-) 465 WP_002355030.1 RNA polymerase sigma factor -
  OZF29_RS12145 (OZF29_12145) gst 2504323..2504832 (-) 510 WP_002370068.1 DinB family glutathione transferase -
  OZF29_RS12150 (OZF29_12150) - 2505165..2506568 (+) 1404 WP_002383291.1 dicarboxylate/amino acid:cation symporter -
  OZF29_RS12155 (OZF29_12155) - 2506666..2507508 (-) 843 WP_116495167.1 LEM-3-like GIY-YIG domain-containing protein -
  OZF29_RS12160 (OZF29_12160) rlmH 2507556..2508035 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  OZF29_RS12165 (OZF29_12165) htrA 2508436..2509734 (+) 1299 WP_116495166.1 S1C family serine protease Regulator
  OZF29_RS12170 (OZF29_12170) ytpR 2509781..2510401 (-) 621 WP_002361057.1 YtpR family tRNA-binding protein -
  OZF29_RS12175 (OZF29_12175) - 2510612..2511067 (-) 456 WP_002385249.1 universal stress protein -
  OZF29_RS12180 (OZF29_12180) - 2511215..2511529 (-) 315 WP_116495165.1 thioredoxin family protein -
  OZF29_RS12185 (OZF29_12185) pepA 2511541..2512617 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  OZF29_RS12190 (OZF29_12190) - 2512924..2513265 (+) 342 WP_002355012.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44861.98 Da        Isoelectric Point: 4.9968

>NTDB_id=763264 OZF29_RS12165 WP_116495166.1 2508436..2509734(+) (htrA) [Enterococcus faecalis strain M61]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNESTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=763264 OZF29_RS12165 WP_116495166.1 2508436..2509734(+) (htrA) [Enterococcus faecalis strain M61]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCATGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAAGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTGGATAAAGCACAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAGTTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCGATTGCGATTG
GTTCCCCTCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCTATTAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGTGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGCATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGTCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(9-416)

PDZ domain (PDZ_2)

(319-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.171

94.907

0.505
  htrA Streptococcus mutans UA159

58.791

84.259

0.495
  htrA Streptococcus mitis NCTC 12261

55.135

85.648

0.472
  htrA Streptococcus pneumoniae TIGR4

55.807

81.713

0.456
  htrA Streptococcus pneumoniae Rx1

55.807

81.713

0.456
  htrA Streptococcus pneumoniae D39

55.807

81.713

0.456
  htrA Streptococcus pneumoniae R6

55.807

81.713

0.456