Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   OQG81_RS12040 Genome accession   NZ_CP113440
Coordinates   2291710..2292942 (+) Length   410 a.a.
NCBI ID   WP_307777631.1    Uniprot ID   -
Organism   Streptococcus macedonicus strain E37     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2286710..2297942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OQG81_RS12025 (OQG81_12020) - 2289510..2290529 (+) 1020 Protein_2315 IS30 family transposase -
  OQG81_RS12035 (OQG81_12030) rlmH 2290987..2291466 (-) 480 WP_014295514.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  OQG81_RS12040 (OQG81_12035) htrA 2291710..2292942 (+) 1233 WP_307777631.1 S1C family serine protease Regulator
  OQG81_RS12045 (OQG81_12040) spo0J 2293012..2293788 (+) 777 WP_058621987.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 42575.08 Da        Isoelectric Point: 4.0556

>NTDB_id=762317 OQG81_RS12040 WP_307777631.1 2291710..2292942(+) (htrA) [Streptococcus macedonicus strain E37]
MPKFNYKNWLKPLGVILVGFIAGVAGTILVLNMAGISITNVGGSSTKTTTSSVSYSNSNDTTKAVEKVQDAVVSVINYKS
DSSSSTSDLYNQFFGNDSDSSSDSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLADGTKVVGELVGA
DTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGKTISTNAIQTDA
AINPGNSGGALINIEGQVIGINSSKISSTSSSGEFVEGMGFAIPSNDVVSIINQLEENGQVIRPALGISMVNLSDLSTNA
IAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDKEVTSTSDLQSILYTHSVGDSVKVTFYRGTDKKTATIKLT
KTTQDLSSSN

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=762317 OQG81_RS12040 WP_307777631.1 2291710..2292942(+) (htrA) [Streptococcus macedonicus strain E37]
TTGCCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCATTTTAGTCGGCTTTATAGCTGGTGTCGCAGGTAC
AATACTCGTCCTAAATATGGCAGGTATTTCAATCACTAACGTCGGTGGTTCAAGTACAAAAACAACAACAAGTAGCGTAA
GCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAAGACGCAGTTGTATCTGTTATTAACTACAAATCA
GACTCGTCGTCTTCTACAAGTGACCTCTACAATCAATTCTTTGGCAATGATTCAGACAGTAGTAGCGATTCAAGCTCTAC
AGATGATTTGACTGTTTACAGTGAAGGTTCTGGGGTTATTTACAAAAAAGATGGTGATTCTGCTTATGTCGTCACTAACA
ATCACGTTATTGATGGGGCTGAACAAATTGAAATCATGCTTGCTGATGGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCA
GATACTTATTCAGATATTGCCGTTGTCAAAATTTCTTCTGACAACGTATCTACAGTTGCTGAATTTGCCGATTCTGATAA
ATTAACTGTCGGTGAAACTGCTATTGCTATTGGTAGCCCACTCGGTACTGAATATGCTAACTCTGTAACACAAGGTATTG
TCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTAAAACTATCTCAACAAATGCTATCCAAACGGATGCA
GCGATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGGACAAGTTATCGGTATCAATTCAAGTAAGATTTC
ATCTACATCAAGTTCTGGTGAATTTGTCGAAGGTATGGGATTTGCCATTCCATCTAACGATGTTGTATCCATTATTAACC
AATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCAATGGTAAACTTGAGCGACCTTTCAACAAATGCA
ATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGTGGCGGCTGTTCAATCTGGTATGCCAGCTGAAGG
TAATCTCGAACAATATGATGTCATCACAGCTATTGACGACAAAGAAGTAACATCTACTTCAGATCTTCAAAGTATCCTTT
ATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGAACTGATAAGAAAACAGCCACAATTAAATTAACT
AAGACAACACAAGATTTATCTTCCTCAAACTGA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(116-261)

PDZ domain (PDZ_2)

(304-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.691

98.78

0.639
  htrA Streptococcus gordonii str. Challis substr. CH1

60.049

99.512

0.598
  htrA Streptococcus pneumoniae D39

58.809

98.293

0.578
  htrA Streptococcus pneumoniae TIGR4

58.809

98.293

0.578
  htrA Streptococcus pneumoniae R6

58.809

98.293

0.578
  htrA Streptococcus pneumoniae Rx1

58.809

98.293

0.578
  htrA Streptococcus mitis NCTC 12261

58.561

98.293

0.576