Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   OQG81_RS10805 Genome accession   NZ_CP113440
Coordinates   2058274..2058588 (-) Length   104 a.a.
NCBI ID   WP_058621376.1    Uniprot ID   A0A2G3NS94
Organism   Streptococcus macedonicus strain E37     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2053274..2063588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OQG81_RS10770 (OQG81_10765) rmuC 2054005..2055279 (-) 1275 WP_014295293.1 DNA recombination protein RmuC -
  OQG81_RS10775 (OQG81_10770) - 2055281..2055910 (-) 630 WP_265643941.1 thiamine diphosphokinase -
  OQG81_RS10780 (OQG81_10775) rpe 2055907..2056566 (-) 660 WP_014295295.1 ribulose-phosphate 3-epimerase -
  OQG81_RS10785 (OQG81_10780) rsgA 2056573..2057445 (-) 873 WP_014295296.1 ribosome small subunit-dependent GTPase A -
  OQG81_RS10800 (OQG81_10795) - 2057887..2058144 (-) 258 WP_014295297.1 hypothetical protein -
  OQG81_RS10805 (OQG81_10800) comD/comD3 2058274..2058588 (-) 315 WP_058621376.1 GHKL domain-containing protein Regulator
  OQG81_RS10810 (OQG81_10805) - 2059162..2059473 (-) 312 WP_014295300.1 bacteriocin immunity protein -
  OQG81_RS10815 (OQG81_10810) - 2059485..2059634 (-) 150 WP_014295301.1 hypothetical protein -
  OQG81_RS10820 (OQG81_10815) - 2059644..2059823 (-) 180 WP_014295302.1 DUF3884 family protein -
  OQG81_RS10825 (OQG81_10820) - 2059765..2059944 (-) 180 WP_014295303.1 hypothetical protein -
  OQG81_RS10830 (OQG81_10825) - 2060165..2060305 (+) 141 WP_014295304.1 hypothetical protein -
  OQG81_RS10835 (OQG81_10830) - 2060323..2061630 (-) 1308 WP_014295305.1 sensor histidine kinase -
  OQG81_RS10840 (OQG81_10835) comE/comE1 2061638..2062369 (-) 732 WP_265643940.1 response regulator transcription factor Regulator
  OQG81_RS10845 (OQG81_10840) - 2062386..2062712 (-) 327 WP_265643939.1 LytTR family DNA-binding domain-containing protein -
  OQG81_RS12270 - 2063176..2063259 (-) 84 Protein_2086 topology modulation protein -

Sequence

Protein


Download         Length: 104 a.a.        Molecular weight: 11772.26 Da        Isoelectric Point: 5.0616

>NTDB_id=762312 OQG81_RS10805 WP_058621376.1 2058274..2058588(-) (comD/comD3) [Streptococcus macedonicus strain E37]
MDCFEIPRITYIHSLAILFDNRIEATVLSGVPKISVANFYQDDNFVFMIENSTKEDSIPIDNVNQKGYSSKGNNRGIGLA
TVIEFHQEYGKLPIETSSSNHLFR

Nucleotide


Download         Length: 315 bp        

>NTDB_id=762312 OQG81_RS10805 WP_058621376.1 2058274..2058588(-) (comD/comD3) [Streptococcus macedonicus strain E37]
ATGGATTGTTTCGAAATTCCACGTATTACCTACATTCATAGCCTTGCTATTCTGTTTGATAATAGGATTGAAGCTACAGT
ATTATCAGGTGTTCCTAAAATATCCGTAGCGAATTTTTATCAAGATGATAACTTTGTTTTTATGATTGAAAATTCAACCA
AAGAAGATAGTATTCCGATTGATAACGTTAATCAAAAAGGCTATTCAAGCAAAGGTAATAATCGTGGTATTGGCTTAGCA
ACAGTTATTGAATTTCATCAAGAATATGGCAAGCTACCCATTGAAACAAGCAGCTCAAATCACCTCTTTAGATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(13-103)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2G3NS94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

57.576

95.192

0.548
  comD/comD2 Streptococcus equinus JB1

56.122

94.231

0.529
  comD/comD1 Streptococcus equinus JB1

47.959

94.231

0.452
  comD/blpH Streptococcus mutans UA159

43

96.154

0.413