Detailed information NTG0762313

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: OQG81_RS10840
• Genome accession: NZ_CP113440
• Coordinates: 2061638..2062369 (-)
• Length: 243 a.a.
• NCBI ID: WP_265643940.1
• Uniprot ID: A0AA47FC06
• Organism: Streptococcus macedonicus strain E37
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2056638..2067369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OQG81_RS10800 (OQG81_10795)	-	2057887..2058144 (-)	258	WP_014295297.1	hypothetical protein	-
OQG81_RS10805 (OQG81_10800)	comD/comD3	2058274..2058588 (-)	315	WP_058621376.1	GHKL domain-containing protein	Regulator
OQG81_RS10810 (OQG81_10805)	-	2059162..2059473 (-)	312	WP_014295300.1	bacteriocin immunity protein	-
OQG81_RS10815 (OQG81_10810)	-	2059485..2059634 (-)	150	WP_014295301.1	hypothetical protein	-
OQG81_RS10820 (OQG81_10815)	-	2059644..2059823 (-)	180	WP_014295302.1	DUF3884 family protein	-
OQG81_RS10825 (OQG81_10820)	-	2059765..2059944 (-)	180	WP_014295303.1	hypothetical protein	-
OQG81_RS10830 (OQG81_10825)	-	2060165..2060305 (+)	141	WP_014295304.1	hypothetical protein	-
OQG81_RS10835 (OQG81_10830)	-	2060323..2061630 (-)	1308	WP_014295305.1	sensor histidine kinase	-
OQG81_RS10840 (OQG81_10835)	comE/comE1	2061638..2062369 (-)	732	WP_265643940.1	response regulator transcription factor	Regulator
OQG81_RS10845 (OQG81_10840)	-	2062386..2062712 (-)	327	WP_265643939.1	LytTR family DNA-binding domain-containing protein	-
OQG81_RS12270	-	2063176..2063259 (-)	84	Protein_2086	topology modulation protein	-
OQG81_RS10850 (OQG81_10845)	-	2063566..2064735 (-)	1170	WP_039671238.1	MFS transporter	-
OQG81_RS10855 (OQG81_10850)	-	2064728..2065783 (-)	1056	WP_265643938.1	ThiF family adenylyltransferase	-
OQG81_RS10860 (OQG81_10855)	-	2066138..2067313 (+)	1176	WP_265644278.1	IS256-like element IS1191 family transposase	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28379.49 Da
• Isoelectric Point: 5.2356

>NTDB_id=762313 OQG81_RS10840 WP_265643940.1 2061638..2062369(-) (comE/comE1) [Streptococcus macedonicus strain E37]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREK
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRVLYSDIL
YFETSPAVHRVILHTKNERVEFYATIAEIAKSDKCLFKCHRSFIINVDNVVRFDRATRSVYFETGDTCLVSRDKIKPLLN
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=762313 OQG81_RS10840 WP_265643940.1 2061638..2062369(-) (comE/comE1) [Streptococcus macedonicus strain E37]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGGTGTTTAGTTCTGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCTATTCGTGAAAAA
GATGCAACAGCTATCATTGTTTTTGTAACAACTCATTCAGAATTTATGCTGCTGACCTACCAAGCGTTAGTAGGGGCAAT
TGATTTTATTGATAAGAACCTGAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCAATGAAACATC
AAAATGATAATTTCGGCGAAAATTCTTTTTTATTTGAAACTCCTAAAGCACGTGTGCGCGTTCTATATAGTGACATTCTT
TATTTCGAAACATCTCCTGCCGTGCACCGCGTGATTTTGCATACGAAAAATGAAAGAGTGGAATTTTATGCGACGATTGC
AGAGATTGCTAAATCAGACAAATGTCTTTTCAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTTAGATTTG
ATAGAGCGACACGAAGTGTTTATTTCGAAACTGGGGACACTTGCCTAGTTTCTAGAGATAAAATAAAACCTCTATTAAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-238)

• Response regulator receiver domain (Response_reg) (11-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	71.605	100	0.716
comE/blpR	Streptococcus mutans UA159	48.536	98.354	0.477
comE/comE2	Streptococcus equinus JB1	46.281	99.588	0.461