Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   OQG81_RS02135 Genome accession   NZ_CP113440
Coordinates   380839..381594 (+) Length   251 a.a.
NCBI ID   WP_014293967.1    Uniprot ID   A0A2G3NXG9
Organism   Streptococcus macedonicus strain E37     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 375839..386594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OQG81_RS02120 (OQG81_02120) - 376247..377818 (-) 1572 WP_014293964.1 ABC transporter permease subunit -
  OQG81_RS02125 (OQG81_02125) - 377952..379847 (+) 1896 WP_048816335.1 DUF2207 domain-containing protein -
  OQG81_RS02130 (OQG81_02130) - 379899..380738 (+) 840 WP_014293966.1 undecaprenyl-diphosphate phosphatase -
  OQG81_RS02135 (OQG81_02135) mecA 380839..381594 (+) 756 WP_014293967.1 adaptor protein MecA Regulator
  OQG81_RS02140 (OQG81_02140) - 381596..382759 (+) 1164 WP_014293968.1 glycosyltransferase family 4 protein -
  OQG81_RS02145 (OQG81_02145) sufC 382872..383642 (+) 771 WP_014293969.1 Fe-S cluster assembly ATPase SufC -
  OQG81_RS02150 (OQG81_02150) sufD 383716..384978 (+) 1263 WP_014293970.1 Fe-S cluster assembly protein SufD -
  OQG81_RS02155 (OQG81_02155) - 384980..386212 (+) 1233 WP_014293971.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28850.66 Da        Isoelectric Point: 4.0627

>NTDB_id=762277 OQG81_RS02135 WP_014293967.1 380839..381594(+) (mecA) [Streptococcus macedonicus strain E37]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSIMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMISKGDTEAHEKLGKIEEMMEGAVEDVLTEQVQAEPTEEDINPSDYVHYV
LDFPTLEAVVSFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVTKLKMIELI

Nucleotide


Download         Length: 756 bp        

>NTDB_id=762277 OQG81_RS02135 WP_014293967.1 380839..381594(+) (mecA) [Streptococcus macedonicus strain E37]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATCTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAATAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTAACGCCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATT
AATAAAGAAATTAACTTTGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGATTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATTGAAGAAATGATGGAAGGTGCTG
TTGAGGATGTTCTCACAGAACAAGTTCAAGCAGAGCCAACAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTATCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGTGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCATCCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTACAAAATTAAAAATGATTGAGTTGATATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2G3NXG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.935

98.805

0.661
  mecA Streptococcus thermophilus LMD-9

59.514

98.406

0.586
  mecA Streptococcus thermophilus LMG 18311

59.109

98.406

0.582
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.49