Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   OS912_RS06215 Genome accession   NZ_CP113266
Coordinates   1223365..1224027 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain BC1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1218365..1229027
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS06190 (OS912_06195) - 1218515..1218781 (-) 267 WP_001278167.1 Veg family protein -
  OS912_RS06195 (OS912_06200) dnaB 1218783..1220135 (-) 1353 WP_000852486.1 replicative DNA helicase -
  OS912_RS06200 (OS912_06205) rplI 1220179..1220631 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  OS912_RS06205 (OS912_06210) - 1220628..1222601 (-) 1974 WP_000715124.1 DHH family phosphoesterase -
  OS912_RS06210 (OS912_06215) hpf 1222737..1223285 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  OS912_RS06215 (OS912_06220) comFC/cflB 1223365..1224027 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  OS912_RS06220 (OS912_06225) comFA/cflA 1224024..1225322 (-) 1299 WP_044813853.1 DEAD/DEAH box helicase Machinery gene
  OS912_RS06225 (OS912_06230) - 1225378..1226013 (+) 636 WP_268232847.1 YigZ family protein -
  OS912_RS06230 (OS912_06235) cysK 1226298..1227218 (+) 921 WP_000029860.1 cysteine synthase A -
  OS912_RS06235 (OS912_06240) - 1227293..1227831 (-) 539 Protein_1199 IS66 family transposase -
  OS912_RS06240 (OS912_06245) - 1227804..1228091 (+) 288 Protein_1200 transposase -
  OS912_RS06245 (OS912_06250) tnpB 1228268..1228555 (-) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=761425 OS912_RS06215 WP_000649971.1 1223365..1224027(-) (comFC/cflB) [Streptococcus pneumoniae strain BC1]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=761425 OS912_RS06215 WP_000649971.1 1223365..1224027(-) (comFC/cflB) [Streptococcus pneumoniae strain BC1]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CGACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914