Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   OS912_RS01935 Genome accession   NZ_CP113266
Coordinates   397616..398353 (-) Length   245 a.a.
NCBI ID   WP_268232975.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 392616..403353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS01915 (OS912_01920) msrB 394075..395013 (-) 939 WP_000818207.1 peptide-methionine (R)-S-oxide reductase MsrB -
  OS912_RS01920 (OS912_01925) - 395080..395232 (-) 153 WP_001852357.1 hypothetical protein -
  OS912_RS01925 (OS912_01930) thrB 395308..396177 (-) 870 WP_000692438.1 homoserine kinase -
  OS912_RS01930 (OS912_01935) - 396179..397465 (-) 1287 WP_000216382.1 homoserine dehydrogenase -
  OS912_RS01935 (OS912_01940) mecA 397616..398353 (-) 738 WP_268232975.1 adaptor protein MecA Regulator
  OS912_RS01940 (OS912_01945) - 398553..399587 (-) 1035 WP_000461498.1 hypothetical protein -
  OS912_RS01945 (OS912_01950) - 399616..401049 (-) 1434 WP_000565096.1 O-antigen polysaccharide polymerase Wzy family protein -
  OS912_RS01950 (OS912_01955) - 401065..402051 (-) 987 WP_000446980.1 glycosyltransferase family 2 protein -
  OS912_RS01955 (OS912_01960) - 402053..403156 (-) 1104 WP_000225894.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28451.32 Da        Isoelectric Point: 4.0557

>NTDB_id=761382 OS912_RS01935 WP_268232975.1 397616..398353(-) (mecA) [Streptococcus pneumoniae strain BC1]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPKEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADRTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDSDISRSVLQEYGQVLMSHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=761382 OS912_RS01935 WP_268232975.1 397616..398353(-) (mecA) [Streptococcus pneumoniae strain BC1]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGAATGGAGAT
TGCTGACTTTCTCGTTCCTAAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGCTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTGCCAGATATGGAAGAATTGGCTCAAATGTCTCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGACAGAACCAAGGATGATATCGAAGCCATTCAATCTCTTGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAAGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGTTTTTGCCAAGACAGTGACTTTTGAAATGGAAACTTCTGAACTCTACAAAATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGCCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCAGAGGATAGTGATATCAGTCGCTCAGTCTTACAAGAGTATGGTCAAGTCTTGATGAGTCACGATGCAGTGCTCAAT
CTGCAAAAAATCGGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

97.959

100

0.98
  mecA Streptococcus pneumoniae D39

97.959

100

0.98
  mecA Streptococcus pneumoniae R6

97.959

100

0.98
  mecA Streptococcus pneumoniae TIGR4

97.551

100

0.976
  mecA Streptococcus thermophilus LMD-9

47.39

100

0.482
  mecA Streptococcus mutans UA159

48.163

100

0.482
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.478