Detailed information NTG0760413

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: OTU47_RS03770
• Genome accession: NZ_CP113115
• Coordinates: 713132..713593 (+)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 708132..718593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTU47_RS03720 (OTU47_03720)	-	709493..709609 (+)	117	WP_001063632.1	hypothetical protein	-
OTU47_RS03725 (OTU47_03725)	-	709590..709793 (+)	204	WP_001091107.1	hypothetical protein	-
OTU47_RS03730 (OTU47_03730)	-	709796..710146 (+)	351	WP_054368148.1	hypothetical protein	-
OTU47_RS03735 (OTU47_03735)	-	710156..710455 (+)	300	WP_001811580.1	hypothetical protein	-
OTU47_RS03740 (OTU47_03740)	-	710459..710794 (+)	336	WP_001186204.1	phage holin	-
OTU47_RS03745 (OTU47_03745)	lytA	710794..711750 (+)	957	WP_054436120.1	N-acetylmuramoyl-L-alanine amidase LytA	-
OTU47_RS03750 (OTU47_03750)	-	711982..712239 (+)	258	WP_000698513.1	hypothetical protein	-
OTU47_RS03755 (OTU47_03755)	comGC/cglC	712241..712507 (+)	267	WP_050073122.1	competence type IV pilus major pilin ComGC	Machinery gene
OTU47_RS03760 (OTU47_03760)	comGD/cglD	712500..712904 (+)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
OTU47_RS03765 (OTU47_03765)	comGE/cglE	712867..713169 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
OTU47_RS03770 (OTU47_03770)	comGF/cglF	713132..713593 (+)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
OTU47_RS03775 (OTU47_03775)	comGG/cglG	713571..713984 (+)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
OTU47_RS03780 (OTU47_03780)	-	714121..714715 (+)	595	Protein_727	class I SAM-dependent methyltransferase	-
OTU47_RS03785 (OTU47_03785)	comYH	714776..715729 (+)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
OTU47_RS03790 (OTU47_03790)	-	715780..716970 (+)	1191	WP_000167766.1	acetate kinase	-
OTU47_RS03795 (OTU47_03795)	-	716971..717102 (+)	132	WP_000768904.1	hypothetical protein	-
OTU47_RS03800 (OTU47_03800)	rnpA	717119..717490 (+)	372	WP_000739246.1	ribonuclease P protein component	-
OTU47_RS03805 (OTU47_03805)	-	717465..718289 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=760413 OTU47_RS03770 WP_000250542.1 713132..713593(+) (comGF/cglF) [Streptococcus pneumoniae strain NP2]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=760413 OTU47_RS03770 WP_000250542.1 713132..713593(+) (comGF/cglF) [Streptococcus pneumoniae strain NP2]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909