Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   OTU47_RS02480 Genome accession   NZ_CP113115
Coordinates   481488..482150 (+) Length   220 a.a.
NCBI ID   WP_000649978.1    Uniprot ID   A0A0E8ARN2
Organism   Streptococcus pneumoniae strain NP2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 476488..487150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU47_RS02450 (OTU47_02450) tnpB 477054..477269 (+) 216 WP_235786183.1 IS66 family insertion sequence element accessory protein TnpB -
  OTU47_RS02455 (OTU47_02455) - 477424..477711 (-) 288 Protein_477 transposase -
  OTU47_RS02460 (OTU47_02460) - 477684..478222 (+) 539 Protein_478 transposase -
  OTU47_RS02465 (OTU47_02465) cysK 478297..479217 (-) 921 WP_000029869.1 cysteine synthase A -
  OTU47_RS02470 (OTU47_02470) - 479502..480137 (-) 636 WP_000395739.1 YigZ family protein -
  OTU47_RS02475 (OTU47_02475) comFA/cflA 480193..481491 (+) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  OTU47_RS02480 (OTU47_02480) comFC/cflB 481488..482150 (+) 663 WP_000649978.1 ComF family protein Machinery gene
  OTU47_RS02485 (OTU47_02485) hpf 482230..482778 (+) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  OTU47_RS02490 (OTU47_02490) - 482914..484887 (+) 1974 WP_000715109.1 DHH family phosphoesterase -
  OTU47_RS02495 (OTU47_02495) rplI 484884..485336 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  OTU47_RS02500 (OTU47_02500) dnaB 485379..486731 (+) 1353 WP_000852486.1 replicative DNA helicase -
  OTU47_RS02505 (OTU47_02505) - 486733..486999 (+) 267 WP_044814445.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25240.11 Da        Isoelectric Point: 7.7116

>NTDB_id=760400 OTU47_RS02480 WP_000649978.1 481488..482150(+) (comFC/cflB) [Streptococcus pneumoniae strain NP2]
MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=760400 OTU47_RS02480 WP_000649978.1 481488..482150(+) (comFC/cflB) [Streptococcus pneumoniae strain NP2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATAATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E8ARN2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909