Detailed information NTG0760373

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: OTU45_RS10800
• Genome accession: NZ_CP113114
• Coordinates: 2095007..2095309 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2090007..2100309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTU45_RS10765 (OTU45_10765)	rnpA	2090686..2091057 (-)	372	WP_000739246.1	ribonuclease P protein component	-
OTU45_RS10770 (OTU45_10770)	-	2091074..2091205 (-)	132	WP_000768904.1	hypothetical protein	-
OTU45_RS10775 (OTU45_10775)	-	2091206..2092396 (-)	1191	WP_000167766.1	acetate kinase	-
OTU45_RS10780 (OTU45_10780)	comYH	2092447..2093400 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
OTU45_RS10785 (OTU45_10785)	-	2093461..2094055 (-)	595	Protein_2108	class I SAM-dependent methyltransferase	-
OTU45_RS10790 (OTU45_10790)	comGG/cglG	2094192..2094605 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
OTU45_RS10795 (OTU45_10795)	comGF/cglF	2094583..2095044 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
OTU45_RS10800 (OTU45_10800)	comGE/cglE	2095007..2095309 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
OTU45_RS10805 (OTU45_10805)	comGD/cglD	2095272..2095676 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
OTU45_RS10810 (OTU45_10810)	comGC/cglC	2095669..2095935 (-)	267	WP_050073122.1	competence type IV pilus major pilin ComGC	Machinery gene
OTU45_RS10815 (OTU45_10815)	-	2095937..2096194 (-)	258	WP_000698513.1	hypothetical protein	-
OTU45_RS10820 (OTU45_10820)	lytA	2096426..2097382 (-)	957	WP_054436120.1	N-acetylmuramoyl-L-alanine amidase LytA	-
OTU45_RS10825 (OTU45_10825)	-	2097382..2097717 (-)	336	WP_001186204.1	phage holin	-
OTU45_RS10830 (OTU45_10830)	-	2097721..2098020 (-)	300	WP_001811580.1	hypothetical protein	-
OTU45_RS10835 (OTU45_10835)	-	2098030..2098380 (-)	351	WP_054368148.1	hypothetical protein	-
OTU45_RS10840 (OTU45_10840)	-	2098383..2098586 (-)	204	WP_001091107.1	hypothetical protein	-
OTU45_RS10845 (OTU45_10845)	-	2098567..2098683 (-)	117	WP_001063632.1	hypothetical protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=760373 OTU45_RS10800 WP_000413382.1 2095007..2095309(-) (comGE/cglE) [Streptococcus pneumoniae strain NP1]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=760373 OTU45_RS10800 WP_000413382.1 2095007..2095309(-) (comGE/cglE) [Streptococcus pneumoniae strain NP1]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4